| 3 | Sun Sep 22 | at Steelers | 1:00 PM | 2-0 | 1.000 | Acrisure Stadium · Pittsburgh, PA |
| 4 | Sun Sep 29 | vs Chiefs | 4:25 PM | 2-0 | 1.000 | SoFi Stadium · Inglewood, CA |
| 6 | Sun Oct 13 | at Broncos | 4:05 PM | 0-2 | .000 | Empower Field at Mile High · Denver, CO |
| 7 | Mon Oct 21 | at Cardinals | 9:00 PM | 1-1 | .500 | State Farm Stadium · Glendale, AZ |
| 8 | Sun Oct 27 | vs Saints | 4:05 PM | 2-0 | 1.000 | SoFi Stadium · Inglewood, CA |
| 9 | Sun Nov 3 | at Browns | 1:00 PM | 1-1 | .500 | FirstEnergy Stadium · Cleveland, OH |
| 10 | Sun Nov 10 | vs Titans | 4:05 PM | 0-2 | .000 | SoFi Stadium · Inglewood, CA |
| 11 | Sun Nov 17 | vs Bengals | 4:25 PM | 0-2 | .000 | SoFi Stadium · Inglewood, CA |
| 12 | Mon Nov 25 | vs Ravens | 8:15 PM | 0-2 | .000 | SoFi Stadium · Inglewood, CA |
| 13 | Sun Dec 1 | at Falcons | 1:00 PM | 1-1 | .500 | Mercedes-Benz Stadium · Atlanta, GA |
| 14 | Sun Dec 8 | atChiefs | 8:20 PM | 2-0 | 1.000 | Arrowhead Stadium · Kansas City, MO |
| 15 | Sun Dec 15 | vs Buccaneers | 4:25 PM | 2-0 | 1.000 | SoFi Stadium · Inglewood, CA |
| 16 | Sun Dec 22 | vsBroncos | 4:05 PM | 0-2 | .000 | SoFi Stadium · Inglewood, CA |
| 17 | TBD | at Patriots | TBD | 1-1 | .500 | Gillette Stadium · Foxborough, MA |
| 18 | TBD | at Raiders | TBD | 1-1 | .500 | Allegiant Stadium · Las Vegas, NV |
Panthers