| 1 | Tue Nov 7 | vs Mount St Mary | W68-53 | 1-0 | 1.000 | - | | XFINITY Center · College Park, MD |
| 2 | Fri Nov 10 | atDavidson | L61-64 | 1-1 | .500 | - | ESPNU | John M. Belk Arena · Davidson, NC |
| 3 | Sun Nov 12 | atUAB | L63-66 | 1-2 | .333 | - | ESPN2 | Bartow Arena · Birmingham, AL |
| 4 | Fri Nov 17 | at21Villanova | L40-57 | 1-3 | .250 | - | FS1 | Finneran Pavilion · Villanova, PA |
| 5 | Tue Nov 21 | vsUMBC | W92-68 | 2-3 | .400 | - | BTN | XFINITY Center · College Park, MD |
| 6 | Sat Nov 25 | vsSouth Alabama | W68-55 | 3-3 | .500 | - | BTN | XFINITY Center · College Park, MD |
| 7 | Tue Nov 28 | vsRider | W103-76 | 4-3 | .571 | - | | XFINITY Center · College Park, MD |
| 8 | Fri Dec 1 | atIndiana | L53-65 | 4-4 | .500 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 9 | Wed Dec 6 | vsPenn State | W81-75 (OT) | 5-4 | .556 | - | BTN | XFINITY Center · College Park, MD |
| 10 | Tue Dec 12 | vsAlcorn St | W105-65 | 6-4 | .600 | - | BTN | XFINITY Center · College Park, MD |
| 11 | Tue Dec 19 | vsNicholls | W73-67 | 7-4 | .636 | - | BTN | XFINITY Center · College Park, MD |
| 12 | Fri Dec 22 | atUCLA | W69-60 | 8-4 | .667 | - | ESPN2 | Pauley Pavilion · Los Angeles, CA |
| 13 | Thu Dec 28 | vsCoppin St | W75-53 | 9-4 | .692 | - | BTN | XFINITY Center · College Park, MD |
| 14 | Tue Jan 2 | vs1Purdue | L53-67 | 9-5 | .643 | - | | XFINITY Center · College Park, MD |
| 15 | Sun Jan 7 | atMinnesota | L62-65 | 9-6 | .600 | - | | Williams Arena · Minneapolis, MN |
| 16 | Thu Jan 11 | vsMichigan | W64-57 | 10-6 | .625 | - | FS1 | XFINITY Center · College Park, MD |
| 17 | Sun Jan 14 | at10Illinois | W76-67 | 11-6 | .647 | - | BTN | State Farm Center · Champaign, IL |
| 18 | Wed Jan 17 | atNorthwestern | L69-72 | 11-7 | .611 | - | BTN | Welsh-Ryan Arena · Evanston, IL |
| 19 | Sun Jan 21 | vsMichigan St | L59-61 | 11-8 | .579 | - | CBS | XFINITY Center · College Park, MD |
| 20 | Wed Jan 24 | atIowa | W69-67 | 12-8 | .600 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 21 | Sat Jan 27 | vsNebraska | W73-51 | 13-8 | .619 | - | BTN | XFINITY Center · College Park, MD |
| 22 | Sat Feb 3 | atMichigan St | L54-63 | 13-9 | .591 | - | FOX | Breslin Center · East Lansing, MI |
| 23 | Tue Feb 6 | vsRutgers | L53-56 | 13-10 | .565 | - | BTN | XFINITY Center · College Park, MD |
| 24 | Sat Feb 10 | atOhio State | L75-79 (2OT) | 13-11 | .542 | - | FS1 | Value City Arena · Columbus, OH |
| 25 | Wed Feb 14 | vsIowa | W78-66 | 14-11 | .560 | - | BTN | XFINITY Center · College Park, MD |
| 26 | Sat Feb 17 | vs14Illinois | L80-85 | 14-12 | .538 | - | FOX | XFINITY Center · College Park, MD |
| 27 | Tue Feb 20 | atWisconsin | L70-74 | 14-13 | .519 | - | | Kohl Center · Madison, WI |
| 28 | Sun Feb 25 | atRutgers | W63-46 | 15-13 | .536 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 29 | Wed Feb 28 | vsNorthwestern | L61-68 | 15-14 | .517 | - | BTN | XFINITY Center · College Park, MD |
| 30 | Sun Mar 3 | vsIndiana | L78-83 | 15-15 | .500 | - | CBS | XFINITY Center · College Park, MD |
| 31 | Sun Mar 10 | atPenn State | L69-85 | 15-16 | .484 | - | BTN | Bryce Jordan Center · University Park, PA |
| 32 | Wed Mar 13 | vsRutgers | W65-51 | 16-16 | .500 | - | | XFINITY Center · College Park, MD |
| 33 | Thu Mar 14 | atWisconsin | L56-87 | 16-17 | .485 | - | BTN | Kohl Center · Madison, WI |
