| 1 | Mon Nov 7 | vs TBD | W102-46 | 1-0 | 1.000 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 2 | Tue Nov 8 | at Purdue | L53-84 | 1-1 | .500 | - | BTN | Mackey Arena · West Lafayette, IN |
| 3 | Sat Nov 12 | vsTBD | W112-38 | 2-1 | .667 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 4 | Sun Nov 20 | at Iowa State | L53-68 | 2-2 | .500 | - | | James H. Hilton Coliseum · Ames, IA |
| 5 | Wed Nov 23 | vs St Thomas (MN) | L72-76 | 2-3 | .400 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 6 | Sat Nov 26 | vs UC Davis | W87-85 | 3-3 | .500 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 7 | Sun Nov 27 | vs Boston Univ | W67-46 | 4-3 | .571 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 8 | Mon Nov 28 | vs SE Missouri St | W84-68 | 5-3 | .625 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 9 | Thu Dec 1 | at Green Bay | W81-67 | 6-3 | .667 | - | | Resch Center · Ashwaubenon, WI |
| 10 | Sat Dec 3 | vs IU Indy | W74-61 | 7-3 | .700 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 11 | Tue Dec 6 | at Chattanooga | L76-88 | 7-4 | .636 | - | | McKenzie Arena · Chattanooga, TN |
| 12 | Sun Dec 11 | vsTBD | W92-63 | 8-4 | .667 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 14 | Thu Dec 29 | at Oakland | L61-83 | 8-5 | .615 | - | | Athletics Center O'rena · Rochester, MI |
| 15 | Sat Dec 31 | at Detroit Mercy | W84-81 | 9-5 | .643 | - | | Calihan Hall · Detroit, MI |
| 16 | Thu Jan 5 | at Cleveland St | W68-64 (OT) | 10-5 | .667 | - | | Wolstein Center · Cleveland, OH |
| 17 | Sat Jan 7 | at Purdue FW | W74-70 | 11-5 | .688 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 18 | Thu Jan 12 | vs N Kentucky | W80-75 | 12-5 | .706 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 19 | Sat Jan 14 | vs Wright St | L74-78 (OT) | 12-6 | .667 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 20 | Thu Jan 19 | vs Robert Morris | W77-69 | 13-6 | .684 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 21 | Sat Jan 21 | vs Youngstown St | W88-75 | 14-6 | .700 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 22 | Thu Jan 26 | atWright St | L86-93 | 14-7 | .667 | - | | Nutter Center · Dayton, OH |
| 23 | Sat Jan 28 | atN Kentucky | W75-74 | 15-7 | .682 | - | | Truist Arena · Highland Heights, KY |
| 24 | Thu Feb 2 | atIU Indy | W72-69 | 16-7 | .696 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 25 | Mon Feb 6 | vsGreen Bay | L79-80 (OT) | 16-8 | .667 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 26 | Thu Feb 9 | vsDetroit Mercy | W94-89 | 17-8 | .680 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 27 | Sat Feb 11 | vsOakland | W80-77 (OT) | 18-8 | .692 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 28 | Thu Feb 16 | atYoungstown St | L58-87 | 18-9 | .667 | - | | Beeghly Center · Youngstown, OH |
| 29 | Sat Feb 18 | atRobert Morris | L60-80 | 18-10 | .643 | - | | UPMC Events Center · Moon Township, PA |
| 30 | Thu Feb 23 | vsPurdue FW | W96-94 | 19-10 | .655 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 31 | Sat Feb 25 | vsCleveland St | W81-72 | 20-10 | .667 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 32 | Thu Mar 2 | vsWright St | W87-70 | 21-10 | .677 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 33 | Mon Mar 6 | vsCleveland St | L80-93 | 21-11 | .656 | - | ESPN2 | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 34 | Sun Mar 19 | vs Stetson | W87-83 (OT) | 22-11 | .667 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 35 | Mon Mar 20 | vs Charlotte | L65-76 | 22-12 | .647 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
Rhode Island