| 1 | Mon Nov 3 | vs Hampton | 8:00 PM | 17-16 | .515 | - | ESPN+ | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 2 | Sat Nov 8 | atWofford | TBD | 19-16 | .543 | - | ESPN+ | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 3 | Mon Nov 10 | vsLittle Rock | TBD | 19-14 | .576 | - | ESPN+ | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 4 | Wed Nov 12 | atIndiana | TBD | 19-13 | .594 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 5 | Fri Nov 14 | at#10Texas Tech | 8:00 PM | 28-9 | .757 | - | ESPN+ | United Supermarkets Arena · Lubbock, TX |
| 6 | Sat Nov 22 | atWichita St | 7:00 PM | 19-15 | .559 | - | ESPN+ | Charles Koch Arena · Wichita, KS |
| 7 | Tue Nov 25 | vsTBD | TBD | 0-0 | .000 | - | ESPN+ | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 8 | Sat Nov 29 | atAkron | TBD | 28-7 | .800 | - | ESPN+ | James A. Rhodes Arena · Akron, OH |
| 9 | Sat Dec 6 | vsRobert Morris | TBD | 26-9 | .743 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 10 | Sun Dec 14 | vsIndiana St | TBD | 14-18 | .438 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 11 | Fri Dec 19 | vsS Dakota St | 5:00 PM | 20-12 | .625 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 12 | Sun Dec 21 | atCleveland St | 5:00 PM | 23-13 | .639 | - | | Wolstein Center · Cleveland, OH |
| 13 | Mon Dec 29 | vsPurdue FW | TBD | 19-13 | .594 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 14 | Tue Dec 30 | at#24Wisconsin | TBD | 27-10 | .730 | - | | Kohl Center · Madison, WI |
| 15 | Thu Jan 1 | atWright St | TBD | 15-18 | .455 | - | | Nutter Center · Dayton, OH |
| 16 | Mon Jan 5 | atGreen Bay | 7:00 PM | 4-28 | .125 | - | | Resch Center · Ashwaubenon, WI |
| 17 | Fri Jan 9 | vsN Kentucky | TBD | 17-16 | .515 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 18 | Sun Jan 11 | vsIU Indy | TBD | 10-22 | .313 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 19 | Thu Jan 15 | vsOakland | TBD | 16-18 | .471 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 20 | Sun Jan 18 | atPurdue FW | 2:00 PM | 19-13 | .594 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 21 | Thu Jan 22 | atRobert Morris | 7:00 PM | 26-9 | .743 | - | | UPMC Events Center · Moon Township, PA |
| 22 | Sat Jan 24 | atYoungstown St | TBD | 21-13 | .618 | - | | Beeghly Center · Youngstown, OH |
| 23 | Fri Jan 30 | vsWright St | TBD | 15-18 | .455 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 24 | Sun Feb 1 | vsCleveland St | TBD | 23-13 | .639 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 25 | Wed Feb 4 | vsDetroit Mercy | TBD | 8-24 | .250 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 26 | Sat Feb 7 | atN Kentucky | 5:00 PM | 17-16 | .515 | - | | Truist Arena · Highland Heights, KY |
| 27 | Sun Feb 15 | vsGreen Bay | TBD | 4-28 | .125 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 28 | Fri Feb 20 | atDetroit Mercy | 7:00 PM | 8-24 | .250 | - | | Calihan Hall · Detroit, MI |
| 29 | Sun Feb 22 | atOakland | 3:00 PM | 16-18 | .471 | - | | Athletics Center O'rena · Rochester, MI |
| 30 | Wed Feb 25 | vsYoungstown St | TBD | 21-13 | .618 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 31 | Sat Feb 28 | atIU Indy | 2:00 PM | 10-22 | .313 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
