| 1 | Tue Nov 5 | vs UC Riverside | L47-66 | 0-1 | .000 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 2 | Sat Nov 9 | vsSouthern Utah | L78-79 (2OT) | 0-2 | .000 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 3 | Fri Nov 15 | vsS Dakota St | W90-73 | 1-2 | .333 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 4 | Fri Nov 22 | vsSouthern | W93-86 (OT) | 2-2 | .500 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 5 | Mon Nov 25 | vsWashington St | W82-71 | 3-2 | .600 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 6 | Tue Nov 26 | vsGeorge Mason | L66-85 | 3-3 | .500 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 7 | Wed Nov 27 | vsSouth Florida | W74-67 | 4-3 | .571 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 8 | Wed Dec 4 | atGeorgia Tech | L56-73 | 4-4 | .500 | - | ESPNU | McCamish Pavilion · Atlanta, GA |
| 9 | Sat Dec 7 | atCreighton | L76-95 | 4-5 | .444 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 10 | Fri Dec 13 | atIndiana | L90-96 (OT) | 4-6 | .400 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 11 | Sun Dec 15 | vsPurdue | W70-56 | 5-6 | .455 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 12 | Sat Dec 21 | vsNorth Dakota | L74-75 | 5-7 | .417 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 13 | Sun Dec 29 | vsTexas A&M-CC | W73-52 | 6-7 | .462 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 14 | Fri Jan 3 | vsRutgers | L62-79 | 6-8 | .429 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 15 | Tue Jan 7 | vsIowa | W76-70 | 7-8 | .467 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 16 | Sat Jan 11 | atNorthwestern | L57-62 | 7-9 | .438 | - | BTN | Welsh-Ryan Arena · Evanston, IL |
| 17 | Tue Jan 14 | at21Ohio State | L68-80 | 7-10 | .412 | - | FS1 | Value City Arena · Columbus, OH |
| 18 | Sat Jan 18 | vsIndiana | L74-82 | 7-11 | .389 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 19 | Tue Jan 21 | atWisconsin | L68-82 | 7-12 | .368 | - | BTN | Kohl Center · Madison, WI |
| 20 | Sat Jan 25 | at24Rutgers | L72-75 | 7-13 | .350 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 21 | Tue Jan 28 | vsMichigan | L68-79 | 7-14 | .333 | - | ESPNU | Pinnacle Bank Arena · Lincoln, NE |
| 22 | Sat Feb 1 | vs24Penn State | L64-76 | 7-15 | .318 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 23 | Sat Feb 8 | at17Iowa | L72-96 | 7-16 | .304 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 24 | Tue Feb 11 | at9Maryland | L70-72 | 7-17 | .292 | - | BTN | XFINITY Center · College Park, MD |
| 25 | Sat Feb 15 | vsWisconsin | L64-81 | 7-18 | .280 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 26 | Thu Feb 20 | vsMichigan St | L65-86 | 7-19 | .269 | - | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 27 | Mon Feb 24 | atIllinois | L59-71 | 7-20 | .259 | - | BTN | State Farm Center · Champaign, IL |
| 28 | Thu Feb 27 | vs23Ohio State | L54-75 | 7-21 | .250 | - | ESPN2 | Pinnacle Bank Arena · Lincoln, NE |
| 29 | Sun Mar 1 | vsNorthwestern | L76-81 (OT) | 7-22 | .241 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 30 | Thu Mar 5 | at25Michigan | L58-82 | 7-23 | .233 | - | FS1 | Crisler Center · Ann Arbor, MI |
| 31 | Sun Mar 8 | atMinnesota | L75-107 | 7-24 | .226 | - | BTN | Williams Arena · Minneapolis, MN |
| 32 | Wed Mar 11 | atIndiana | L64-89 | 7-25 | .219 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
