| 1 | Mon Nov 7 | vs Maine | W79-66 | 1-0 | 1.000 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 2 | Thu Nov 10 | vs Omaha | W75-61 | 2-0 | 1.000 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 3 | Thu Nov 17 | at St John's | L50-70 | 2-1 | .667 | - | FS1 | Carnesecca Arena · Queens, NY |
| 4 | Sun Nov 20 | vs AR-Pine Bluff | W82-58 | 3-1 | .750 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 5 | Thu Nov 24 | vs Oklahoma | L56-69 | 3-2 | .600 | - | ESPN | Pinnacle Bank Arena · Lincoln, NE |
| 6 | Fri Nov 25 | at Memphis | L61-73 | 3-3 | .500 | - | ESPNEWS | FedExForum · Memphis, TN |
| 7 | Sun Nov 27 | vs Florida St | W75-58 | 4-3 | .571 | - | ESPNEWS | Pinnacle Bank Arena · Lincoln, NE |
| 8 | Wed Nov 30 | vs Boston College | W88-67 | 5-3 | .625 | - | ESPNU | Pinnacle Bank Arena · Lincoln, NE |
| 9 | Sun Dec 4 | at #7Creighton | W63-53 | 6-3 | .667 | - | FS1 | CHI Health Center Omaha · Omaha, NE |
| 10 | Wed Dec 7 | at #14Indiana | L65-81 | 6-4 | .600 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 11 | Sat Dec 10 | vs #4Purdue | L62-65 (OT) | 6-5 | .545 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 12 | Sat Dec 17 | at Kansas St | L56-71 | 6-6 | .500 | - | | Bramlage Coliseum · Manhattan, KS |
| 13 | Tue Dec 20 | vs Queens | W75-65 | 7-6 | .538 | - | | Pinnacle Bank Arena · Lincoln, NE |
| 14 | Thu Dec 29 | vs Iowa | W66-50 | 8-6 | .571 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 15 | Tue Jan 3 | at Michigan St | L56-74 | 8-7 | .533 | - | BTN | Breslin Center · East Lansing, MI |
| 16 | Sat Jan 7 | at Minnesota | W81-79 (OT) | 9-7 | .563 | - | BTN | Williams Arena · Minneapolis, MN |
| 17 | Tue Jan 10 | vs Illinois | L50-76 | 9-8 | .529 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 18 | Fri Jan 13 | at#3Purdue | L55-73 | 9-9 | .500 | - | BTN | Mackey Arena · West Lafayette, IN |
| 19 | Wed Jan 18 | vs Ohio State | W63-60 | 10-9 | .526 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 20 | Sat Jan 21 | at Penn State | L65-76 | 10-10 | .500 | - | BTN | Bryce Jordan Center · University Park, PA |
| 21 | Wed Jan 25 | vs Northwestern | L63-78 | 10-11 | .476 | - | FS2 | Pinnacle Bank Arena · Lincoln, NE |
| 22 | Sat Jan 28 | at Maryland | L63-82 | 10-12 | .455 | - | BTN | XFINITY Center · College Park, MD |
| 23 | Tue Jan 31 | atIllinois | L56-72 | 10-13 | .435 | - | BTN | State Farm Center · Champaign, IL |
| 24 | Sun Feb 5 | vsPenn State | W72-63 | 11-13 | .458 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 25 | Wed Feb 8 | at Michigan | L72-93 | 11-14 | .440 | - | BTN | Crisler Center · Ann Arbor, MI |
| 26 | Sat Feb 11 | vs Wisconsin | W73-63 (OT) | 12-14 | .462 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 27 | Tue Feb 14 | at Rutgers | W82-72 | 13-14 | .481 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 28 | Sun Feb 19 | vsMaryland | W70-66 (OT) | 14-14 | .500 | - | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 29 | Sat Feb 25 | vsMinnesota | W78-67 | 15-14 | .517 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 30 | Tue Feb 28 | vsMichigan St | L67-80 | 15-15 | .500 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 31 | Sun Mar 5 | atIowa | W81-77 | 16-15 | .516 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 32 | Wed Mar 8 | vsMinnesota | L75-78 | 16-16 | .500 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
