| 1 | Mon Nov 3 | vs W Georgia | W86-53 | 1-0 | 1.000 | - | B1G+ | Pinnacle Bank Arena · Lincoln, NE |
| 2 | Sat Nov 8 | vsFIU | W96-66 | 2-0 | 1.000 | - | B1G+ | Pinnacle Bank Arena · Lincoln, NE |
| 3 | Tue Nov 11 | vsMD-Eastern | W69-50 | 3-0 | 1.000 | - | B1G+ | Pinnacle Bank Arena · Lincoln, NE |
| 4 | Sat Nov 15 | vsOklahoma | W105-99 | 4-0 | 1.000 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 5 | Thu Nov 20 | atNew Mexico | W84-72 | 5-0 | 1.000 | - | Peacock | The Pit · Albuquerque, NM |
| 6 | Fri Nov 21 | vsKansas St | W86-85 | 6-0 | 1.000 | - | Peacock | Pinnacle Bank Arena · Lincoln, NE |
| 7 | Tue Nov 25 | vsWinthrop | W80-73 | 7-0 | 1.000 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 8 | Sat Nov 29 | vsSC Upstate | W72-63 | 8-0 | 1.000 | - | B1G+ | Pinnacle Bank Arena · Lincoln, NE |
| 9 | Sun Dec 7 | vsCreighton | W71-50 | 9-0 | 1.000 | - | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 10 | Wed Dec 10 | vsWisconsin | W90-60 | 10-0 | 1.000 | #23 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 11 | Sat Dec 13 | at13Illinois | W83-80 | 11-0 | 1.000 | #23 | Peacock | State Farm Center · Champaign, IL |
| 12 | Sun Dec 21 | vsNorth Dakota | W78-55 | 12-0 | 1.000 | #15 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 13 | Tue Dec 30 | vsNew Hampshire | W86-55 | 13-0 | 1.000 | #13 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 14 | Fri Jan 2 | vs9Michigan St | W58-56 | 14-0 | 1.000 | #13 | Peacock | Pinnacle Bank Arena · Lincoln, NE |
| 15 | Mon Jan 5 | atOhio State | W72-69 | 15-0 | 1.000 | #10 | FS1 | Value City Arena · Columbus, OH |
| 16 | Sat Jan 10 | atIndiana | W83-77 | 16-0 | 1.000 | #10 | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 17 | Tue Jan 13 | vsOregon | W90-55 | 17-0 | 1.000 | #8 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 18 | Sat Jan 17 | atNorthwestern | W77-58 | 18-0 | 1.000 | #8 | BTN | Welsh-Ryan Arena · Evanston, IL |
| 19 | Wed Jan 21 | vsWashington | W76-66 | 19-0 | 1.000 | #7 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 20 | Sat Jan 24 | atMinnesota | W76-57 | 20-0 | 1.000 | #7 | FS1 | Williams Arena · Minneapolis, MN |
| 21 | Tue Jan 27 | at3Michigan | L72-75 | 20-1 | .952 | #5 | Peacock | Crisler Center · Ann Arbor, MI |
| 22 | Sun Feb 1 | vs9Illinois | L69-78 | 20-2 | .909 | #5 | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 23 | Sat Feb 7 | atRutgers | W80-68 | 21-2 | .913 | #9 | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 24 | Tue Feb 10 | vs13Purdue | L77-80 (OT) | 21-3 | .875 | #7 | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 25 | Sat Feb 14 | vsNorthwestern | W68-49 | 22-3 | .880 | #7 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 26 | Tue Feb 17 | atIowa | L52-57 | 22-4 | .846 | #9 | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 27 | Sat Feb 21 | vsPenn State | W87-64 | 23-4 | .852 | #9 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 28 | Wed Feb 25 | vsMaryland | W74-61 | 24-4 | .857 | #12 | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 29 | Sat Feb 28 | atUSC | W82-67 | 25-4 | .862 | #12 | BTN | Galen Center · Los Angeles, CA |
