| 1 | Fri Nov 11 | vs Houston | L55-81 | 0-1 | .000 | - | CBSSN | Alumni Hall (Navy) · Annapolis, MD |
| 2 | Mon Nov 14 | vsLafayette | W63-59 | 1-1 | .500 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 3 | Thu Nov 17 | vsAlbany | W99-79 | 2-1 | .667 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 4 | Mon Nov 21 | vsGeorgia | L53-66 | 2-2 | .500 | - | CBSSN | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 5 | Tue Nov 22 | vsSouth Florida | L62-75 | 2-3 | .400 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 6 | Wed Nov 30 | atPenn | W85-80 (OT) | 3-3 | .500 | - | | The Palestra · Philadelphia, PA |
| 7 | Sat Dec 3 | vsFairleigh | L80-97 | 3-4 | .429 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 8 | Tue Dec 6 | atTemple | L60-70 | 3-5 | .375 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 9 | Sat Dec 10 | vsSaint Peter's | W73-57 | 4-5 | .444 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 10 | Sat Dec 17 | vsVillanova | L64-71 | 4-6 | .400 | - | CBSSN | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 11 | Mon Dec 19 | vsSacred Heart | W77-59 | 5-6 | .455 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 12 | Thu Dec 22 | vsC Connecticut | W83-66 | 6-6 | .500 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 13 | Sat Dec 31 | vsSaint Louis | L78-83 | 6-7 | .462 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 14 | Wed Jan 4 | atDayton | L56-76 | 6-8 | .429 | - | | UD Arena · Dayton, OH |
| 15 | Sat Jan 7 | atFordham | L54-66 | 6-9 | .400 | - | | Rose Hill Gymnasium · Bronx, NY |
| 16 | Wed Jan 11 | vsDuquesne | L80-92 | 6-10 | .375 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 17 | Sat Jan 14 | vsLoyola Chicago | W86-55 | 7-10 | .412 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 18 | Mon Jan 16 | atLa Salle | W71-59 | 8-10 | .444 | - | CBSSN | Tom Gola Arena · Philadelphia, PA |
| 19 | Sat Jan 21 | vsUMass | W74-68 | 9-10 | .474 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 20 | Wed Jan 25 | atG Washington | L91-92 (OT) | 9-11 | .450 | - | | Charles E. Smith Center · Washington, D.C. |
| 21 | Sun Jan 29 | atGeorge Mason | W79-76 | 10-11 | .476 | - | USA Net | EagleBank Arena · Fairfax, VA |
| 22 | Wed Feb 1 | vsRhode Island | W64-50 | 11-11 | .500 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 23 | Sun Feb 5 | vsLa Salle | L65-73 | 11-12 | .478 | - | ESPNU | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 24 | Wed Feb 8 | atLoyola Chicago | W83-71 | 12-12 | .500 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 25 | Sat Feb 11 | vsG Washington | W81-69 | 13-12 | .520 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 26 | Wed Feb 15 | atDuquesne | L62-76 | 13-13 | .500 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 27 | Sat Feb 18 | atDavidson | L75-76 | 13-14 | .481 | - | USA Net | John M. Belk Arena · Davidson, NC |
| 28 | Tue Feb 21 | vsVCU | L63-88 | 13-15 | .464 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 29 | Sun Feb 26 | atSt Bonaventure | L76-89 | 13-16 | .448 | - | USA Net | Reilly Center · Saint Bonaventure, NY |
| 30 | Wed Mar 1 | vsRichmond | W83-67 | 14-16 | .467 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 31 | Tue Mar 7 | vsLoyola Chicago | W72-67 | 15-16 | .484 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 32 | Wed Mar 8 | atG Washington | W87-76 | 16-16 | .500 | - | USA Net | Charles E. Smith Center · Washington, D.C. |
| 33 | Thu Mar 9 | atDayton | L54-60 | 16-17 | .485 | - | USA Net | UD Arena · Dayton, OH |
