| 1 | Mon Nov 6 | at South Carolina | L53-82 | 0-1 | .000 | - | | Colonial Life Arena · Columbia, SC |
| 2 | Fri Nov 10 | at Vanderbilt | L67-74 | 0-2 | .000 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 3 | Sun Nov 12 | vs TBD | W106-48 | 1-2 | .333 | - | | G.B. Hodge Center · Spartanburg, SC |
| 4 | Wed Nov 15 | at E Carolina | W83-81 | 2-2 | .500 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 5 | Sat Nov 18 | at Minnesota | L53-67 | 2-3 | .400 | - | | Williams Arena · Minneapolis, MN |
| 6 | Tue Nov 21 | at Ball State | L58-75 | 2-4 | .333 | - | | Worthen Arena · Muncie, IN |
| 7 | Sat Nov 25 | vsTBD | W79-44 | 3-4 | .429 | - | | G.B. Hodge Center · Spartanburg, SC |
| 8 | Wed Nov 29 | at Coast Car | L70-72 (OT) | 3-5 | .375 | - | | The HTC Center · Conway, SC |
| 9 | Sat Dec 2 | at NC Central | W85-82 | 4-5 | .444 | - | | McDougald-McLendon Arena · Durham, NC |
| 10 | Sat Dec 9 | vs Kennesaw St | L77-84 | 4-6 | .400 | - | | G.B. Hodge Center · Spartanburg, SC |
| 11 | Sat Dec 16 | vs W Carolina | L53-70 | 4-7 | .364 | - | | G.B. Hodge Center · Spartanburg, SC |
| 12 | Thu Dec 21 | at Davidson | L59-62 | 4-8 | .333 | - | | John M. Belk Arena · Davidson, NC |
| 13 | Sat Dec 30 | vsTBD | W96-76 | 5-8 | .385 | - | | G.B. Hodge Center · Spartanburg, SC |
| 14 | Wed Jan 3 | at UNC Asheville | L67-95 | 5-9 | .357 | - | | Kimmel Arena · Asheville, NC |
| 15 | Sat Jan 6 | vs Winthrop | L80-82 (OT) | 5-10 | .333 | - | | G.B. Hodge Center · Spartanburg, SC |
| 16 | Sat Jan 13 | at Charleston So | L70-77 | 5-11 | .313 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 17 | Wed Jan 17 | vs Longwood | W73-71 | 6-11 | .353 | - | | G.B. Hodge Center · Spartanburg, SC |
| 18 | Sat Jan 20 | at Radford | L61-64 | 6-12 | .333 | - | | Donald N. Dedmon Center · Radford, VA |
| 19 | Wed Jan 24 | vs High Point | L67-78 | 6-13 | .316 | - | | G.B. Hodge Center · Spartanburg, SC |
| 20 | Sat Jan 27 | at Gardner-Webb | L70-75 | 6-14 | .300 | - | | Paul Porter Arena · Boiling Springs, NC |
| 21 | Wed Jan 31 | at Presbyterian | L73-80 | 6-15 | .286 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 22 | Sat Feb 3 | vsRadford | W78-69 | 7-15 | .318 | - | | G.B. Hodge Center · Spartanburg, SC |
| 23 | Wed Feb 7 | atLongwood | W69-64 | 8-15 | .348 | - | | Willett Hall · Farmville, VA |
| 24 | Sat Feb 10 | vsUNC Asheville | L64-77 | 8-16 | .333 | - | | G.B. Hodge Center · Spartanburg, SC |
| 25 | Wed Feb 14 | atHigh Point | W86-81 (OT) | 9-16 | .360 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 26 | Sat Feb 17 | vsGardner-Webb | L65-73 | 9-17 | .346 | - | | G.B. Hodge Center · Spartanburg, SC |
| 27 | Wed Feb 21 | vsCharleston So | L60-63 | 9-18 | .333 | - | | G.B. Hodge Center · Spartanburg, SC |
| 28 | Sat Feb 24 | atWinthrop | L74-83 | 9-19 | .321 | - | | Winthrop Coliseum · Rock Hill, SC |
| 29 | Wed Feb 28 | vsPresbyterian | W74-72 | 10-19 | .345 | - | | G.B. Hodge Center · Spartanburg, SC |
| 30 | Wed Mar 6 | vsRadford | L60-67 | 10-20 | .333 | - | | G.B. Hodge Center · Spartanburg, SC |
