| 1 | Wed Dec 2 | vs Oral Roberts | W85-80 | 1-0 | 1.000 | - | | Charles Koch Arena · Wichita, KS |
| 2 | Sun Dec 6 | vsMissouri | L62-72 | 1-1 | .500 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 3 | Sat Dec 12 | vsOklahoma St | L64-67 | 1-2 | .333 | - | | Charles Koch Arena · Wichita, KS |
| 4 | Tue Dec 15 | atTulsa | W69-65 | 2-2 | .500 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 5 | Fri Dec 18 | vsTBD | W73-57 | 3-2 | .600 | - | | Charles Koch Arena · Wichita, KS |
| 6 | Tue Dec 22 | atSouth Florida | W82-77 (OT) | 4-2 | .667 | - | | Yuengling Center · Tampa, FL |
| 7 | Wed Dec 30 | vsTBD | W81-43 | 5-2 | .714 | - | | Charles Koch Arena · Wichita, KS |
| 8 | Sat Jan 2 | atOle Miss | W83-79 | 6-2 | .750 | - | ESPNU | SJB Pavilion · Oxford, MS |
| 9 | Wed Jan 6 | at11Houston | L63-70 | 6-3 | .667 | - | | Fertitta Center · Houston, TX |
| 10 | Sun Jan 10 | vsCincinnati | W82-76 | 7-3 | .700 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 11 | Wed Jan 13 | vsTulsa | W72-53 | 8-3 | .727 | - | | Charles Koch Arena · Wichita, KS |
| 13 | Thu Jan 21 | atMemphis | L52-72 | 8-4 | .667 | - | ESPN2 | FedExForum · Memphis, TN |
| 14 | Sun Jan 24 | vsSouth Florida | PPD | 16-6 | .727 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 16 | Sat Jan 30 | vsUCF | W93-88 (OT) | 9-4 | .692 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 17 | Wed Feb 3 | vsTulane | W75-67 | 10-4 | .714 | - | | Charles Koch Arena · Wichita, KS |
| 18 | Sun Feb 7 | vsTemple | W70-67 | 11-4 | .733 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 19 | Wed Feb 10 | atUCF | W61-60 | 12-4 | .750 | - | | Addition Financial Arena · Orlando, FL |
| 21 | Thu Feb 18 | vs6Houston | W68-63 | 13-4 | .765 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 23 | Sun Feb 28 | vsSMU | PPD | 16-6 | .727 | - | | Charles Koch Arena · Wichita, KS |
| 24 | Wed Mar 3 | atTulane | W78-70 | 14-4 | .778 | - | | Devlin Fieldhouse · New Orleans, LA |
| 25 | Sat Mar 6 | vsSouth Florida | W80-63 | 15-4 | .789 | - | | Charles Koch Arena · Wichita, KS |
| 26 | Fri Mar 12 | vsSouth Florida | W68-67 | 16-4 | .800 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 27 | Sat Mar 13 | vsCincinnati | L59-60 | 16-5 | .762 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 24 | Thu Mar 18 | vs11Drake | L52-53 | 16-6 | .727 | #11 | TBS | Mackey Arena · West Lafayette, IN |
