| 1 | Mon Nov 6 | vs Lipscomb | W76-59 | 1-0 | 1.000 | - | | Charles Koch Arena · Wichita, KS |
| 2 | Thu Nov 9 | vsWestern KY | W71-61 | 2-0 | 1.000 | - | | Charles Koch Arena · Wichita, KS |
| 3 | Sun Nov 12 | vsTBD | W95-65 | 3-0 | 1.000 | - | | Charles Koch Arena · Wichita, KS |
| 4 | Thu Nov 16 | atCoast Car | W86-77 | 4-0 | 1.000 | - | ESPNU | The HTC Center · Conway, SC |
| 5 | Fri Nov 17 | atLiberty | L66-83 | 4-1 | .800 | - | ESPNU | The HTC Center · Conway, SC |
| 6 | Sun Nov 19 | vsSaint Louis | W88-69 | 5-1 | .833 | - | ESPN2 | The HTC Center · Conway, SC |
| 7 | Sat Nov 25 | vsNorfolk St | W80-67 | 6-1 | .857 | - | | Charles Koch Arena · Wichita, KS |
| 8 | Wed Nov 29 | vsRichmond | W80-68 | 7-1 | .875 | - | | Charles Koch Arena · Wichita, KS |
| 9 | Sun Dec 3 | atMissouri | L72-82 | 7-2 | .778 | - | ESPN2 | Mizzou Arena · Columbia, MO |
| 10 | Sat Dec 9 | vsS Dakota St | L69-79 | 7-3 | .700 | - | | Charles Koch Arena · Wichita, KS |
| 11 | Sat Dec 16 | vsS Illinois | W69-68 | 8-3 | .727 | - | | Charles Koch Arena · Wichita, KS |
| 12 | Thu Dec 21 | atKansas St | L60-69 | 8-4 | .667 | - | | T-Mobile Center · Kansas City, MOS |
| 13 | Sat Dec 30 | at2Kansas | L67-86 | 8-5 | .615 | - | ESPN2 | T-Mobile Center · Kansas City, MOS |
| 14 | Thu Jan 4 | vsNorth Texas | L62-74 | 8-6 | .571 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 15 | Sun Jan 7 | atTemple | L61-68 | 8-7 | .533 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 16 | Sun Jan 14 | vs13Memphis | L86-112 | 8-8 | .500 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 17 | Thu Jan 18 | at23FAU | L77-86 | 8-9 | .471 | - | ESPN2 | FAU Arena · Boca Raton, FL |
| 18 | Sun Jan 21 | atSouth Florida | L68-72 | 8-10 | .444 | - | | Yuengling Center · Tampa, FL |
| 19 | Wed Jan 24 | vsE Carolina | L52-54 | 8-11 | .421 | - | | Charles Koch Arena · Wichita, KS |
| 20 | Sun Jan 28 | vsSMU | W77-72 | 9-11 | .450 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 21 | Wed Jan 31 | atTulsa | L68-79 | 9-12 | .429 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 22 | Sat Feb 3 | atMemphis | L63-65 | 9-13 | .409 | - | CBS | FedExForum · Memphis, TN |
| 23 | Wed Feb 7 | vsUTSA | W84-64 | 10-13 | .435 | - | | Charles Koch Arena · Wichita, KS |
| 24 | Sun Feb 11 | vs20FAU | L82-95 (OT) | 10-14 | .417 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 25 | Thu Feb 15 | atE Carolina | L55-68 | 10-15 | .400 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 26 | Sun Feb 18 | atCharlotte | L61-72 | 10-16 | .385 | - | ESPN2 | Dale F. Halton Arena · Charlotte, NC |
| 27 | Wed Feb 21 | vsTulsa | W79-63 | 11-16 | .407 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 28 | Sun Feb 25 | vsTemple | L66-72 (OT) | 11-17 | .393 | - | ESPN | Charles Koch Arena · Wichita, KS |
| 29 | Wed Feb 28 | atUAB | W74-66 | 12-17 | .414 | - | | Bartow Arena · Birmingham, AL |
| 30 | Sat Mar 2 | vsRice | W87-66 | 13-17 | .433 | - | | Charles Koch Arena · Wichita, KS |
| 31 | Fri Mar 8 | atTulane | L75-85 | 13-18 | .419 | - | ESPN2 | Devlin Fieldhouse · New Orleans, LA |
| 32 | Wed Mar 13 | vsRice | W88-81 | 14-18 | .438 | - | | Charles Koch Arena · Wichita, KS |
| 33 | Thu Mar 14 | atMemphis | W71-65 | 15-18 | .455 | - | ESPNU | FedExForum · Memphis, TN |
| 34 | Fri Mar 15 | atUAB | L60-72 | 15-19 | .441 | - | ESPN2 | Bartow Arena · Birmingham, AL |
