| 17 | Mon Nov 25 | vs Magic | 7:00 PM | 11-7 | .611 | Spectrum Center · Charlotte, NC |
| 18 | Wed Nov 27 | vs Heat | 7:00 PM | 6-7 | .462 | Spectrum Center · Charlotte, NC |
| 19 | Fri Nov 29 | vs Knicks | 12:00 PM | 9-7 | .563 | Spectrum Center · Charlotte, NC |
| 20 | Sat Nov 30 | vs Hawks | 6:00 PM | 7-10 | .412 | Spectrum Center · Charlotte, NC |
| 21 | Tue Dec 3 | vs 76ers | 7:00 PM | 3-12 | .200 | Spectrum Center · Charlotte, NC |
| 22 | Thu Dec 5 | atKnicks | 7:30 PM | 9-7 | .563 | Madison Square Garden · Manhattan, NY |
| 23 | Sat Dec 7 | vs Cavaliers | 1:00 PM | 16-1 | .941 | Spectrum Center · Charlotte, NC |
| 24 | Sun Dec 8 | at Pacers | 5:00 PM | 7-10 | .412 | Gainbridge Fieldhouse · Indianapolis, IN |
| 25 | Thu Dec 19 | at Wizards | 7:00 PM | 2-13 | .133 | Capital One Arena · Washington, D.C. |
| 26 | Fri Dec 20 | at76ers | 7:00 PM | 3-12 | .200 | Wells Fargo Center · Philadelphia, PA |
| 27 | Mon Dec 23 | vs Rockets | 7:00 PM | 12-6 | .667 | Spectrum Center · Charlotte, NC |
| 28 | Thu Dec 26 | atWizards | 7:00 PM | 2-13 | .133 | Capital One Arena · Washington, D.C. |
| 29 | Sat Dec 28 | vs Thunder | 6:00 PM | 12-4 | .750 | Spectrum Center · Charlotte, NC |
| 30 | Mon Dec 30 | vs Bulls | 7:00 PM | 7-11 | .389 | Spectrum Center · Charlotte, NC |
| 31 | Fri Jan 3 | at Pistons | 7:00 PM | 7-11 | .389 | Little Caesars Arena · Detroit, MI |
| 32 | Sun Jan 5 | atCavaliers | 6:00 PM | 16-1 | .941 | Rocket Mortgage FieldHouse · Cleveland, OH |
| 33 | Tue Jan 7 | vs Suns | 7:00 PM | 9-7 | .563 | Spectrum Center · Charlotte, NC |
| 34 | Thu Jan 9 | at Lakers | 10:30 PM | 10-6 | .625 | Crypto.com Arena · Los Angeles, CA |
| 35 | Sat Jan 11 | at Clippers | 10:30 PM | 10-7 | .588 | Crypto.com Arena · Los Angeles, CA |
| 36 | Sun Jan 12 | atSuns | 9:00 PM | 9-7 | .563 | Footprint Center · Phoenix, AZ |
| 37 | Wed Jan 15 | at Jazz | 9:00 PM | 4-12 | .250 | Vivint Arena · Salt Lake City, UT |
| 38 | Fri Jan 17 | atBulls | 9:30 PM | 7-11 | .389 | United Center · Chicago, IL |
| 39 | Mon Jan 20 | vs Mavericks | 12:00 PM | 9-7 | .563 | Spectrum Center · Charlotte, NC |
| 40 | Wed Jan 22 | at Grizzlies | 8:00 PM | 10-7 | .588 | FedExForum · Memphis, TN |
| 41 | Fri Jan 24 | vs Blazers | 7:00 PM | 7-10 | .412 | Spectrum Center · Charlotte, NC |
| 42 | Sat Jan 25 | vs Pelicans | 7:00 PM | 4-13 | .235 | Spectrum Center · Charlotte, NC |
| 43 | Mon Jan 27 | vsLakers | 7:00 PM | 10-6 | .625 | Spectrum Center · Charlotte, NC |
| 44 | Wed Jan 29 | vs Nets | 7:00 PM | 6-10 | .375 | Spectrum Center · Charlotte, NC |
| 45 | Fri Jan 31 | vsClippers | 7:00 PM | 10-7 | .588 | Spectrum Center · Charlotte, NC |
| 46 | Sat Feb 1 | vs Nuggets | 7:00 PM | 9-6 | .600 | Spectrum Center · Charlotte, NC |
| 47 | Mon Feb 3 | vsWizards | 7:00 PM | 2-13 | .133 | Spectrum Center · Charlotte, NC |
| 48 | Wed Feb 5 | vs Bucks | 7:00 PM | 8-9 | .471 | Spectrum Center · Charlotte, NC |
| 49 | Fri Feb 7 | vs Spurs | 7:00 PM | 9-8 | .529 | Spectrum Center · Charlotte, NC |
| 50 | Sun Feb 9 | atPistons | 1:00 PM | 7-11 | .389 | Little Caesars Arena · Detroit, MI |
| 51 | Mon Feb 10 | atNets | 7:30 PM | 6-10 | .375 | Barclays Center · Brooklyn, NY |
| 52 | Wed Feb 12 | atMagic | 7:00 PM | 11-7 | .611 | Amway Center · Orlando, FL |
| 53 | Thu Feb 20 | atNuggets | 9:00 PM | 9-6 | .600 | Ball Arena · Denver, CO |
| 54 | Sat Feb 22 | atBlazers | 10:00 PM | 7-10 | .412 | Moda Center · Portland, OR |
| 55 | Mon Feb 24 | at Kings | 10:00 PM | 8-8 | .500 | Golden 1 Center · Sacramento, CA |
| 56 | Tue Feb 25 | at Warriors | 10:00 PM | 12-4 | .750 | Chase Center · San Francisco, CA |
| 57 | Thu Feb 27 | atMavericks | 8:30 PM | 9-7 | .563 | American Airlines Center · Dallas, TX |
| 58 | Sat Mar 1 | vsWizards | 6:00 PM | 2-13 | .133 | Spectrum Center · Charlotte, NC |
| 59 | Mon Mar 3 | vsWarriors | 7:00 PM | 12-4 | .750 | Spectrum Center · Charlotte, NC |
| 60 | Wed Mar 5 | vs T-wolves | 7:00 PM | 8-8 | .500 | Spectrum Center · Charlotte, NC |
| 61 | Fri Mar 7 | vsCavaliers | 7:00 PM | 16-1 | .941 | Spectrum Center · Charlotte, NC |
| 62 | Sat Mar 8 | vsNets | 6:00 PM | 6-10 | .375 | Spectrum Center · Charlotte, NC |
| 63 | Mon Mar 10 | atHeat | 7:30 PM | 6-7 | .462 | FTX Arena · Miami, FL |
| 64 | Wed Mar 12 | atHawks | 7:30 PM | 7-10 | .412 | State Farm Arena · Atlanta, GA |
| 65 | Fri Mar 14 | atSpurs | 8:00 PM | 9-8 | .529 | AT&T Center · San Antonio, TX |
| 66 | Tue Mar 18 | vsHawks | 7:00 PM | 7-10 | .412 | Spectrum Center · Charlotte, NC |
| 67 | Thu Mar 20 | vsKnicks | 7:00 PM | 9-7 | .563 | Spectrum Center · Charlotte, NC |
| 68 | Fri Mar 21 | atThunder | 8:00 PM | 12-4 | .750 | Paycom Center · Oklahoma City, OK |
| 69 | Sun Mar 23 | atHeat | 6:00 PM | 6-7 | .462 | FTX Arena · Miami, FL |
| 70 | Tue Mar 25 | vsMagic | 7:00 PM | 11-7 | .611 | Spectrum Center · Charlotte, NC |
| 71 | Fri Mar 28 | at Raptors | 7:30 PM | 4-12 | .250 | Scotiabank Arena · Toronto, ON |
| 72 | Sun Mar 30 | atPelicans | 7:00 PM | 4-13 | .235 | Smoothie King Center · New Orleans, LA |
| 73 | Mon Mar 31 | vsJazz | 7:00 PM | 4-12 | .250 | Spectrum Center · Charlotte, NC |
| 74 | Wed Apr 2 | atPacers | 7:00 PM | 7-10 | .412 | Gainbridge Fieldhouse · Indianapolis, IN |
| 75 | Fri Apr 4 | vsKings | 7:00 PM | 8-8 | .500 | Spectrum Center · Charlotte, NC |
| 76 | Sun Apr 6 | vsBulls | 1:00 PM | 7-11 | .389 | Spectrum Center · Charlotte, NC |
| 77 | Tue Apr 8 | vsGrizzlies | 7:00 PM | 10-7 | .588 | Spectrum Center · Charlotte, NC |
| 78 | Wed Apr 9 | atRaptors | 7:30 PM | 4-12 | .250 | Scotiabank Arena · Toronto, ON |
| 79 | Fri Apr 11 | at Celtics | 7:30 PM | 14-3 | .824 | TD Garden · Boston, MA |
| 80 | Sun Apr 13 | atCeltics | 1:00 PM | 14-3 | .824 | TD Garden · Boston, MA |
