| 16 | Sat Nov 23 | vs Nuggets | 10:30 PM | 8-5 | .615 | Crypto.com Arena · Los Angeles, CA |
| 17 | Tue Nov 26 | at Suns | 10:00 PM | 9-7 | .563 | Footprint Center · Phoenix, AZ |
| 18 | Wed Nov 27 | at Spurs | 8:30 PM | 8-8 | .500 | AT&T Center · San Antonio, TX |
| 19 | Fri Nov 29 | vs Thunder | 10:00 PM | 12-4 | .750 | Crypto.com Arena · Los Angeles, CA |
| 20 | Sun Dec 1 | at Jazz | 8:00 PM | 3-12 | .200 | Vivint Arena · Salt Lake City, UT |
| 21 | Mon Dec 2 | at T-wolves | 8:00 PM | 8-7 | .533 | Target Center · Minneapolis, MN |
| 22 | Wed Dec 4 | at Heat | 7:30 PM | 6-7 | .462 | FTX Arena · Miami, FL |
| 23 | Fri Dec 6 | at Hawks | 7:30 PM | 7-9 | .438 | State Farm Arena · Atlanta, GA |
| 24 | Sun Dec 8 | vs Blazers | 9:30 PM | 6-9 | .400 | Crypto.com Arena · Los Angeles, CA |
| 25 | Thu Dec 19 | at Kings | 10:00 PM | 8-7 | .533 | Golden 1 Center · Sacramento, CA |
| 26 | Sat Dec 21 | atKings | 6:00 PM | 8-7 | .533 | Golden 1 Center · Sacramento, CA |
| 27 | Mon Dec 23 | vs Pistons | 10:30 PM | 7-10 | .412 | Crypto.com Arena · Los Angeles, CA |
| 28 | Wed Dec 25 | at Warriors | 8:00 PM | 11-3 | .786 | Chase Center · San Francisco, CA |
| 29 | Sat Dec 28 | vsKings | 10:30 PM | 8-7 | .533 | Crypto.com Arena · Los Angeles, CA |
| 30 | Tue Dec 31 | vs Cavaliers | 9:00 PM | 16-1 | .941 | Crypto.com Arena · Los Angeles, CA |
| 31 | Thu Jan 2 | vsBlazers | 10:30 PM | 6-9 | .400 | Crypto.com Arena · Los Angeles, CA |
| 32 | Fri Jan 3 | vsHawks | 10:30 PM | 7-9 | .438 | Crypto.com Arena · Los Angeles, CA |
| 33 | Sun Jan 5 | at Rockets | 7:00 PM | 11-5 | .688 | Toyota Center · Houston, TX |
| 34 | Tue Jan 7 | at Mavericks | 7:30 PM | 8-7 | .533 | American Airlines Center · Dallas, TX |
| 35 | Thu Jan 9 | vs Hornets | 10:30 PM | 6-9 | .400 | Crypto.com Arena · Los Angeles, CA |
| 36 | Sat Jan 11 | vsSpurs | 10:30 PM | 8-8 | .500 | Crypto.com Arena · Los Angeles, CA |
| 37 | Mon Jan 13 | vsSpurs | 10:30 PM | 8-8 | .500 | Crypto.com Arena · Los Angeles, CA |
| 38 | Wed Jan 15 | vsHeat | 10:00 PM | 6-7 | .462 | Crypto.com Arena · Los Angeles, CA |
| 39 | Fri Jan 17 | vs Nets | 10:30 PM | 6-9 | .400 | Crypto.com Arena · Los Angeles, CA |
| 40 | Sun Jan 19 | at Clippers | 9:00 PM | 9-7 | .563 | Crypto.com Arena · Los Angeles, CA |
| 41 | Tue Jan 21 | vs Wizards | 10:30 PM | 2-11 | .154 | Crypto.com Arena · Los Angeles, CA |
| 42 | Thu Jan 23 | vs Celtics | 10:00 PM | 12-3 | .800 | Crypto.com Arena · Los Angeles, CA |
| 43 | Sat Jan 25 | atWarriors | 8:30 PM | 11-3 | .786 | Chase Center · San Francisco, CA |
| 44 | Mon Jan 27 | atHornets | 7:00 PM | 6-9 | .400 | Spectrum Center · Charlotte, NC |
| 45 | Tue Jan 28 | at 76ers | 7:30 PM | 2-12 | .143 | Wells Fargo Center · Philadelphia, PA |
| 46 | Thu Jan 30 | atWizards | 7:00 PM | 2-11 | .154 | Capital One Arena · Washington, D.C. |
| 47 | Sat Feb 1 | at Knicks | 8:30 PM | 9-6 | .600 | Madison Square Garden · Manhattan, NY |
| 48 | Tue Feb 4 | atClippers | 10:00 PM | 9-7 | .563 | Crypto.com Arena · Los Angeles, CA |
| 49 | Thu Feb 6 | vsWarriors | 10:00 PM | 11-3 | .786 | Crypto.com Arena · Los Angeles, CA |
| 50 | Sat Feb 8 | vs Pacers | 4:00 PM | 6-9 | .400 | Crypto.com Arena · Los Angeles, CA |
| 51 | Tue Feb 11 | vsJazz | 10:30 PM | 3-12 | .200 | Crypto.com Arena · Los Angeles, CA |
| 52 | Wed Feb 12 | atJazz | 9:00 PM | 3-12 | .200 | Vivint Arena · Salt Lake City, UT |
| 53 | Thu Feb 20 | atBlazers | 10:00 PM | 6-9 | .400 | Moda Center · Portland, OR |
| 54 | Sat Feb 22 | atNuggets | 8:30 PM | 8-5 | .615 | Ball Arena · Denver, CO |
| 55 | Tue Feb 25 | vsMavericks | 10:00 PM | 8-7 | .533 | Crypto.com Arena · Los Angeles, CA |
| 56 | Thu Feb 27 | vsT-wolves | 10:30 PM | 8-7 | .533 | Crypto.com Arena · Los Angeles, CA |
| 57 | Fri Feb 28 | vsClippers | 10:00 PM | 9-7 | .563 | Crypto.com Arena · Los Angeles, CA |
| 58 | Sun Mar 2 | vsClippers | 9:30 PM | 9-7 | .563 | Crypto.com Arena · Los Angeles, CA |
| 59 | Tue Mar 4 | vs Pelicans | 10:30 PM | 4-12 | .250 | Crypto.com Arena · Los Angeles, CA |
| 60 | Thu Mar 6 | vsKnicks | 10:00 PM | 9-6 | .600 | Crypto.com Arena · Los Angeles, CA |
| 61 | Sat Mar 8 | atCeltics | 8:30 PM | 12-3 | .800 | TD Garden · Boston, MA |
| 62 | Mon Mar 10 | atNets | 7:30 PM | 6-9 | .400 | Barclays Center · Brooklyn, NY |
| 63 | Thu Mar 13 | at Bucks | 7:30 PM | 6-9 | .400 | Fiserv Forum · Milwaukee, WI |
| 64 | Fri Mar 14 | atNuggets | 9:30 PM | 8-5 | .615 | Ball Arena · Denver, CO |
| 65 | Sun Mar 16 | vsSuns | 3:30 PM | 9-7 | .563 | Crypto.com Arena · Los Angeles, CA |
| 66 | Tue Mar 18 | vsBucks | 10:30 PM | 6-9 | .400 | Crypto.com Arena · Los Angeles, CA |
| 67 | Wed Mar 19 | vsNuggets | 10:00 PM | 8-5 | .615 | Crypto.com Arena · Los Angeles, CA |
| 68 | Sat Mar 22 | vs Bulls | 10:30 PM | 6-10 | .375 | Crypto.com Arena · Los Angeles, CA |
| 69 | Mon Mar 24 | at Magic | 7:00 PM | 10-7 | .588 | Amway Center · Orlando, FL |
| 70 | Wed Mar 26 | atPacers | 7:30 PM | 6-9 | .400 | Gainbridge Fieldhouse · Indianapolis, IN |
| 71 | Thu Mar 27 | atBulls | 8:00 PM | 6-10 | .375 | United Center · Chicago, IL |
| 72 | Sat Mar 29 | at Grizzlies | 8:00 PM | 9-7 | .563 | FedExForum · Memphis, TN |
| 73 | Mon Mar 31 | vsRockets | 10:30 PM | 11-5 | .688 | Crypto.com Arena · Los Angeles, CA |
| 74 | Thu Apr 3 | vsWarriors | 10:00 PM | 11-3 | .786 | Crypto.com Arena · Los Angeles, CA |
| 75 | Fri Apr 4 | vsPelicans | 10:30 PM | 4-12 | .250 | Crypto.com Arena · Los Angeles, CA |
| 76 | Sun Apr 6 | atThunder | 3:30 PM | 12-4 | .750 | Paycom Center · Oklahoma City, OK |
| 77 | Tue Apr 8 | atThunder | 8:00 PM | 12-4 | .750 | Paycom Center · Oklahoma City, OK |
| 78 | Wed Apr 9 | atMavericks | 7:30 PM | 8-7 | .533 | American Airlines Center · Dallas, TX |
| 79 | Fri Apr 11 | vsRockets | 10:30 PM | 11-5 | .688 | Crypto.com Arena · Los Angeles, CA |
| 80 | Sun Apr 13 | atBlazers | 3:30 PM | 6-9 | .400 | Moda Center · Portland, OR |
Raptors