| 1 | Tue Oct 21 | vs Rockets | 7:30 PM | 0-0 | .000 | NBC | Paycom Center · Oklahoma City, OK |
| 2 | Thu Oct 23 | atPacers | 7:30 PM | 0-0 | .000 | ESPN | Gainbridge Fieldhouse · Indianapolis, IN |
| 3 | Sat Oct 25 | atHawks | 7:30 PM | 0-0 | .000 | | State Farm Arena · Atlanta, GA |
| 4 | Mon Oct 27 | atMavericks | 8:30 PM | 0-0 | .000 | | American Airlines Center · Dallas, TX |
| 5 | Tue Oct 28 | vsKings | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 6 | Thu Oct 30 | vsWizards | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 7 | Sun Nov 2 | vsPelicans | 3:30 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 8 | Tue Nov 4 | atClippers | 11:00 PM | 0-0 | .000 | NBC | Intuit Dome · Inglewood, CA |
| 9 | Wed Nov 5 | atBlazers | 10:00 PM | 0-0 | .000 | | Moda Center · Portland, OR |
| 10 | Fri Nov 7 | atKings | 10:00 PM | 0-0 | .000 | | Golden 1 Center · Sacramento, CA |
| 11 | Sun Nov 9 | atGrizzlies | 6:00 PM | 0-0 | .000 | | FedExForum · Memphis, TN |
| 12 | Tue Nov 11 | vsWarriors | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 13 | Wed Nov 12 | vsLakers | 9:30 PM | 0-0 | .000 | ESPN | Paycom Center · Oklahoma City, OK |
| 14 | Sat Nov 15 | atHornets | 7:00 PM | 0-0 | .000 | | Spectrum Center · Charlotte, NC |
| 15 | Mon Nov 17 | atPelicans | 8:00 PM | 0-0 | .000 | | Smoothie King Center · New Orleans, LA |
| 16 | Wed Nov 19 | vsKings | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 17 | Fri Nov 21 | atJazz | 10:00 PM | 0-0 | .000 | | Vivint Arena · Salt Lake City, UT |
| 18 | Sun Nov 23 | vsBlazers | 7:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 19 | Wed Nov 26 | vsT-wolves | 7:30 PM | 0-0 | .000 | ESPN | Paycom Center · Oklahoma City, OK |
| 20 | Fri Nov 28 | vsSuns | 9:30 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 21 | Sun Nov 30 | atBlazers | 6:00 PM | 0-0 | .000 | | Moda Center · Portland, OR |
| 22 | Tue Dec 2 | atWarriors | 11:00 PM | 0-0 | .000 | NBC | Chase Center · San Francisco, CA |
| 23 | Fri Dec 5 | vsMavericks | 9:30 PM | 0-0 | .000 | Amazon | Paycom Center · Oklahoma City, OK |
| 24 | Sun Dec 7 | atJazz | 8:00 PM | 0-0 | .000 | | Vivint Arena · Salt Lake City, UT |
| 25 | Wed Dec 17 | vsClippers | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 26 | Fri Dec 19 | atT-wolves | 9:30 PM | 0-0 | .000 | Amazon | Target Center · Minneapolis, MN |
| 27 | Mon Dec 22 | vsGrizzlies | 9:30 PM | 0-0 | .000 | Peacock | Paycom Center · Oklahoma City, OK |
| 28 | Tue Dec 23 | atSpurs | 8:30 PM | 0-0 | .000 | | AT&T Center · San Antonio, TX |
| 29 | Thu Dec 25 | vsSpurs | 2:30 PM | 0-0 | .000 | ABC | Paycom Center · Oklahoma City, OK |
| 30 | Sun Dec 28 | vs76ers | 3:30 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 31 | Mon Dec 29 | vsHawks | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 32 | Wed Dec 31 | vsBlazers | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 33 | Fri Jan 2 | atWarriors | 10:00 PM | 0-0 | .000 | Amazon | Chase Center · San Francisco, CA |
| 34 | Sun Jan 4 | atSuns | 8:00 PM | 0-0 | .000 | | Footprint Center · Phoenix, AZ |
| 35 | Mon Jan 5 | vsHornets | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 36 | Wed Jan 7 | vsJazz | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 37 | Fri Jan 9 | atGrizzlies | 8:00 PM | 0-0 | .000 | | FedExForum · Memphis, TN |
| 38 | Sun Jan 11 | vsHeat | 7:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 39 | Tue Jan 13 | vsSpurs | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 40 | Thu Jan 15 | atRockets | 7:30 PM | 0-0 | .000 | Amazon | Toyota Center · Houston, TX |
| 41 | Sat Jan 17 | atHeat | 8:00 PM | 0-0 | .000 | | Kaseya Center · Miami, FL |
| 42 | Mon Jan 19 | atCavaliers | 2:30 PM | 0-0 | .000 | NBC | Rocket Mortgage FieldHouse · Cleveland, OH |
| 43 | Wed Jan 21 | atBucks | 9:30 PM | 0-0 | .000 | ESPN | Fiserv Forum · Milwaukee, WI |
| 44 | Fri Jan 23 | vsPacers | 9:30 PM | 0-0 | .000 | Amazon | Paycom Center · Oklahoma City, OK |
| 45 | Sun Jan 25 | vsRaptors | 7:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 46 | Tue Jan 27 | vsPelicans | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 47 | Thu Jan 29 | atT-wolves | 9:30 PM | 0-0 | .000 | Amazon | Target Center · Minneapolis, MN |
| 48 | Sun Feb 1 | atNuggets | 9:30 PM | 0-0 | .000 | NBC | Ball Arena · Denver, CO |
| 49 | Tue Feb 3 | vsMagic | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 50 | Wed Feb 4 | atSpurs | 9:30 PM | 0-0 | .000 | ESPN | AT&T Center · San Antonio, TX |
| 51 | Sat Feb 7 | vsRockets | 3:30 PM | 0-0 | .000 | ABC | Paycom Center · Oklahoma City, OK |
| 52 | Mon Feb 9 | atLakers | 10:00 PM | 0-0 | .000 | Peacock | Crypto.com Arena · Los Angeles, CA |
| 53 | Wed Feb 11 | atSuns | 9:00 PM | 0-0 | .000 | | Footprint Center · Phoenix, AZ |
| 54 | Thu Feb 12 | vsBucks | 7:30 PM | 0-0 | .000 | Amazon | Paycom Center · Oklahoma City, OK |
| 55 | Fri Feb 20 | vsNets | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 56 | Sun Feb 22 | vsCavaliers | 1:00 PM | 0-0 | .000 | ABC | Paycom Center · Oklahoma City, OK |
| 57 | Tue Feb 24 | atRaptors | 7:30 PM | 0-0 | .000 | | Scotiabank Arena · Toronto, ON |
| 58 | Wed Feb 25 | atPistons | 7:00 PM | 0-0 | .000 | | Little Caesars Arena · Detroit, MI |
| 59 | Fri Feb 27 | vsNuggets | 9:30 PM | 0-0 | .000 | ESPN | Paycom Center · Oklahoma City, OK |
| 60 | Sun Mar 1 | atMavericks | 8:00 PM | 0-0 | .000 | NBC | American Airlines Center · Dallas, TX |
| 61 | Tue Mar 3 | atBulls | 8:00 PM | 0-0 | .000 | | United Center · Chicago, IL |
| 62 | Wed Mar 4 | atKnicks | 7:00 PM | 0-0 | .000 | ESPN | Madison Square Garden · Manhattan, NY |
| 63 | Sat Mar 7 | vsWarriors | 8:30 PM | 0-0 | .000 | ABC | Paycom Center · Oklahoma City, OK |
| 64 | Mon Mar 9 | vsNuggets | 7:30 PM | 0-0 | .000 | Peacock | Paycom Center · Oklahoma City, OK |
| 65 | Thu Mar 12 | vsCeltics | 9:30 PM | 0-0 | .000 | Amazon | Paycom Center · Oklahoma City, OK |
| 66 | Sun Mar 15 | vsT-wolves | 1:00 PM | 0-0 | .000 | ABC | Paycom Center · Oklahoma City, OK |
| 67 | Tue Mar 17 | atMagic | 7:00 PM | 0-0 | .000 | | Amway Center · Orlando, FL |
| 68 | Wed Mar 18 | atNets | 7:30 PM | 0-0 | .000 | | Barclays Center · Brooklyn, NY |
| 69 | Sat Mar 21 | atWizards | 5:00 PM | 0-0 | .000 | | Capital One Arena · Washington, D.C. |
| 70 | Mon Mar 23 | at76ers | 7:00 PM | 0-0 | .000 | | Wells Fargo Center · Philadelphia, PA |
| 71 | Wed Mar 25 | atCeltics | 7:30 PM | 0-0 | .000 | | TD Garden · Boston, MA |
| 72 | Fri Mar 27 | vsBulls | 8:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 73 | Sun Mar 29 | vsKnicks | 7:30 PM | 0-0 | .000 | NBC | Paycom Center · Oklahoma City, OK |
| 74 | Mon Mar 30 | vsPistons | 9:30 PM | 0-0 | .000 | Peacock | Paycom Center · Oklahoma City, OK |
| 75 | Thu Apr 2 | vsLakers | 7:30 PM | 0-0 | .000 | Amazon | Paycom Center · Oklahoma City, OK |
| 76 | Sun Apr 5 | vsJazz | 7:00 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
| 77 | Tue Apr 7 | atLakers | 10:30 PM | 0-0 | .000 | | Crypto.com Arena · Los Angeles, CA |
| 78 | Wed Apr 8 | atClippers | 10:00 PM | 0-0 | .000 | ESPN | Intuit Dome · Inglewood, CA |
| 79 | Fri Apr 10 | atNuggets | 10:00 PM | 0-0 | .000 | Amazon | Ball Arena · Denver, CO |
| 80 | Sun Apr 12 | vsSuns | 8:30 PM | 0-0 | .000 | | Paycom Center · Oklahoma City, OK |
