| 1 | Tue Oct 22 | at Clippers | L102-112 | 0-1 | .000 | Crypto.com Arena · Los Angeles, CA |
| 2 | Fri Oct 25 | vs Jazz | W95-86 | 1-1 | .500 | Crypto.com Arena · Los Angeles, CA |
| 3 | Sun Oct 27 | vs Hornets | W120-101 | 2-1 | .667 | Crypto.com Arena · Los Angeles, CA |
| 4 | Tue Oct 29 | vs Grizzlies | W120-91 | 3-1 | .750 | Crypto.com Arena · Los Angeles, CA |
| 5 | Fri Nov 1 | at Mavericks | W119-110 (OT) | 4-1 | .800 | American Airlines Center · Dallas, TX |
| 6 | Sun Nov 3 | at Spurs | W103-96 | 5-1 | .833 | AT&T Center · San Antonio, TX |
| 7 | Tue Nov 5 | at Bulls | W118-112 | 6-1 | .857 | United Center · Chicago, IL |
| 8 | Fri Nov 8 | vs Heat | W95-80 | 7-1 | .875 | Crypto.com Arena · Los Angeles, CA |
| 9 | Sun Nov 10 | vs Raptors | L104-113 | 7-2 | .778 | Crypto.com Arena · Los Angeles, CA |
| 10 | Tue Nov 12 | at Suns | W123-115 | 8-2 | .800 | Footprint Center · Phoenix, AZ |
| 11 | Wed Nov 13 | vs Warriors | W120-94 | 9-2 | .818 | Crypto.com Arena · Los Angeles, CA |
| 12 | Fri Nov 15 | vs Kings | W99-97 | 10-2 | .833 | Crypto.com Arena · Los Angeles, CA |
| 13 | Sun Nov 17 | vs Hawks | W122-101 | 11-2 | .846 | Crypto.com Arena · Los Angeles, CA |
| 14 | Tue Nov 19 | vs Thunder | W112-107 | 12-2 | .857 | Crypto.com Arena · Los Angeles, CA |
| 15 | Fri Nov 22 | atThunder | W130-127 | 13-2 | .867 | Paycom Center · Oklahoma City, OK |
| 16 | Sat Nov 23 | atGrizzlies | W109-108 | 14-2 | .875 | FedExForum · Memphis, TN |
| 17 | Mon Nov 25 | atSpurs | W114-104 | 15-2 | .882 | AT&T Center · San Antonio, TX |
| 18 | Wed Nov 27 | at Pelicans | W114-110 | 16-2 | .889 | Smoothie King Center · New Orleans, LA |
| 19 | Fri Nov 29 | vs Wizards | W125-103 | 17-2 | .895 | Crypto.com Arena · Los Angeles, CA |
| 20 | Sun Dec 1 | vsMavericks | L100-114 | 17-3 | .850 | Crypto.com Arena · Los Angeles, CA |
| 21 | Tue Dec 3 | at Nuggets | W105-96 | 18-3 | .857 | Ball Arena · Denver, CO |
| 22 | Wed Dec 4 | atJazz | W121-96 | 19-3 | .864 | Vivint Arena · Salt Lake City, UT |
| 23 | Fri Dec 6 | at Blazers | W136-113 | 20-3 | .870 | Moda Center · Portland, OR |
| 24 | Sun Dec 8 | vs T-wolves | W142-125 | 21-3 | .875 | Crypto.com Arena · Los Angeles, CA |
| 25 | Wed Dec 11 | at Magic | W96-87 | 22-3 | .880 | Amway Center · Orlando, FL |
| 26 | Fri Dec 13 | atHeat | W113-110 | 23-3 | .885 | FTX Arena · Miami, FL |
| 27 | Sun Dec 15 | atHawks | W101-96 | 24-3 | .889 | State Farm Arena · Atlanta, GA |
| 28 | Tue Dec 17 | at Pacers | L102-105 | 24-4 | .857 | Gainbridge Fieldhouse · Indianapolis, IN |
| 29 | Thu Dec 19 | at Bucks | L104-111 | 24-5 | .828 | Fiserv Forum · Milwaukee, WI |
| 30 | Sun Dec 22 | vsNuggets | L104-128 | 24-6 | .800 | Crypto.com Arena · Los Angeles, CA |
| 31 | Wed Dec 25 | vsClippers | L106-111 | 24-7 | .774 | Crypto.com Arena · Los Angeles, CA |
| 32 | Sat Dec 28 | atBlazers | W128-120 | 25-7 | .781 | Moda Center · Portland, OR |
| 33 | Sun Dec 29 | vsMavericks | W108-95 | 26-7 | .788 | Crypto.com Arena · Los Angeles, CA |
| 34 | Wed Jan 1 | vsSuns | W117-107 | 27-7 | .794 | Crypto.com Arena · Los Angeles, CA |
| 35 | Fri Jan 3 | vsPelicans | W123-113 | 28-7 | .800 | Crypto.com Arena · Los Angeles, CA |
| 36 | Sun Jan 5 | vs Pistons | W106-99 | 29-7 | .806 | Crypto.com Arena · Los Angeles, CA |
| 37 | Tue Jan 7 | vs Knicks | W117-87 | 30-7 | .811 | Crypto.com Arena · Los Angeles, CA |
| 38 | Fri Jan 10 | atMavericks | W129-114 | 31-7 | .816 | American Airlines Center · Dallas, TX |
| 39 | Sat Jan 11 | atThunder | W125-110 | 32-7 | .821 | Paycom Center · Oklahoma City, OK |
| 40 | Mon Jan 13 | vs Cavaliers | W128-99 | 33-7 | .825 | Crypto.com Arena · Los Angeles, CA |
| 41 | Wed Jan 15 | vsMagic | L118-119 | 33-8 | .805 | Crypto.com Arena · Los Angeles, CA |
| 42 | Sat Jan 18 | at Rockets | W124-115 | 34-8 | .810 | Toyota Center · Houston, TX |
| 43 | Mon Jan 20 | at Celtics | L107-139 | 34-9 | .791 | TD Garden · Boston, MA |
| 44 | Wed Jan 22 | atKnicks | W100-92 | 35-9 | .795 | Madison Square Garden · Manhattan, NY |
| 45 | Thu Jan 23 | at Nets | W128-113 | 36-9 | .800 | Barclays Center · Brooklyn, NY |
| 46 | Sat Jan 25 | at 76ers | L91-108 | 36-10 | .783 | Wells Fargo Center · Philadelphia, PA |
| 47 | Fri Jan 31 | vsBlazers | L119-127 | 36-11 | .766 | Crypto.com Arena · Los Angeles, CA |
| 48 | Sat Feb 1 | atKings | W129-113 | 37-11 | .771 | Golden 1 Center · Sacramento, CA |
| 49 | Tue Feb 4 | vsSpurs | W129-102 | 38-11 | .776 | Crypto.com Arena · Los Angeles, CA |
| 50 | Thu Feb 6 | vsRockets | L111-121 | 38-12 | .760 | Crypto.com Arena · Los Angeles, CA |
| 51 | Sat Feb 8 | atWarriors | W125-120 | 39-12 | .765 | Chase Center · San Francisco, CA |
| 52 | Mon Feb 10 | vsSuns | W125-100 | 40-12 | .769 | Crypto.com Arena · Los Angeles, CA |
| 53 | Wed Feb 12 | atNuggets | W120-116 (OT) | 41-12 | .774 | Ball Arena · Denver, CO |
| 54 | Fri Feb 21 | vsGrizzlies | W117-105 | 42-12 | .778 | Crypto.com Arena · Los Angeles, CA |
| 55 | Sun Feb 23 | vsCeltics | W114-112 | 43-12 | .782 | Crypto.com Arena · Los Angeles, CA |
| 56 | Tue Feb 25 | vsPelicans | W118-109 | 44-12 | .786 | Crypto.com Arena · Los Angeles, CA |
| 57 | Thu Feb 27 | atWarriors | W116-86 | 45-12 | .789 | Chase Center · San Francisco, CA |
| 58 | Sat Feb 29 | atGrizzlies | L88-105 | 45-13 | .776 | FedExForum · Memphis, TN |
| 59 | Sun Mar 1 | atPelicans | W122-114 | 46-13 | .780 | Smoothie King Center · New Orleans, LA |
| 60 | Tue Mar 3 | vs76ers | W120-107 | 47-13 | .783 | Crypto.com Arena · Los Angeles, CA |
| 61 | Fri Mar 6 | vsBucks | W113-103 | 48-13 | .787 | Crypto.com Arena · Los Angeles, CA |
| 62 | Sun Mar 8 | atClippers | W112-103 | 49-13 | .790 | Crypto.com Arena · Los Angeles, CA |
| 63 | Tue Mar 10 | vsNets | L102-104 | 49-14 | .778 | Crypto.com Arena · Los Angeles, CA |
| 64 | Thu Jul 30 | vsClippers | W103-101 | 50-14 | .781 | Crypto.com Arena · Los Angeles, CA |
| 65 | Sat Aug 1 | atRaptors | L92-107 | 50-15 | .769 | Scotiabank Arena · Toronto, ON |
| 66 | Mon Aug 3 | atJazz | W116-108 | 51-15 | .773 | Vivint Arena · Salt Lake City, UT |
| 67 | Wed Aug 5 | vsThunder | L86-105 | 51-16 | .761 | Crypto.com Arena · Los Angeles, CA |
| 68 | Thu Aug 6 | atRockets | L97-113 | 51-17 | .750 | Toyota Center · Houston, TX |
| 69 | Sat Aug 8 | atPacers | L111-116 | 51-18 | .739 | Gainbridge Fieldhouse · Indianapolis, IN |
| 70 | Mon Aug 10 | vsNuggets | W124-121 | 52-18 | .743 | Crypto.com Arena · Los Angeles, CA |
| 71 | Thu Aug 13 | vsKings | L122-136 | 52-19 | .732 | Crypto.com Arena · Los Angeles, CA |
| 1 | Tue Aug 18 | vsBlazers | L93-100 | 0-1 | .000 | Crypto.com Arena · Los Angeles, CA |
| 2 | Thu Aug 20 | vsBlazers | W111-88 | 1-1 | .500 | Crypto.com Arena · Los Angeles, CA |
| 3 | Sat Aug 22 | atBlazers | W116-108 | 2-1 | .667 | Moda Center · Portland, OR |
| 4 | Mon Aug 24 | atBlazers | W135-115 | 3-1 | .750 | Moda Center · Portland, OR |
| 5 | Sat Aug 29 | vsBlazers | W131-122 | 4-1 | .800 | Crypto.com Arena · Los Angeles, CA |
| 1 | Fri Sep 4 | vsRockets | L97-112 | 0-1 | .000 | Crypto.com Arena · Los Angeles, CA |
| 2 | Sun Sep 6 | vsRockets | W117-109 | 1-1 | .500 | Crypto.com Arena · Los Angeles, CA |
| 3 | Tue Sep 8 | atRockets | W112-102 | 2-1 | .667 | Toyota Center · Houston, TX |
| 4 | Thu Sep 10 | atRockets | W110-100 | 3-1 | .750 | Toyota Center · Houston, TX |
| 5 | Sat Sep 12 | vsRockets | W119-96 | 4-1 | .800 | Crypto.com Arena · Los Angeles, CA |
| 1 | Fri Sep 18 | vsNuggets | W126-114 | 1-0 | 1.000 | Crypto.com Arena · Los Angeles, CA |
| 2 | Sun Sep 20 | vsNuggets | W105-103 | 2-0 | 1.000 | Crypto.com Arena · Los Angeles, CA |
| 3 | Tue Sep 22 | atNuggets | L106-114 | 2-1 | .667 | Ball Arena · Denver, CO |
| 4 | Thu Sep 24 | atNuggets | W114-108 | 3-1 | .750 | Ball Arena · Denver, CO |
| 5 | Sat Sep 26 | vsNuggets | W117-107 | 4-1 | .800 | Crypto.com Arena · Los Angeles, CA |
| 1 | Wed Sep 30 | vsHeat | W116-98 | 1-0 | 1.000 | Crypto.com Arena · Los Angeles, CA |
| 2 | Fri Oct 2 | vsHeat | W124-114 | 2-0 | 1.000 | Crypto.com Arena · Los Angeles, CA |
| 3 | Sun Oct 4 | atHeat | L104-115 | 2-1 | .667 | FTX Arena · Miami, FL |
| 4 | Tue Oct 6 | atHeat | W102-96 | 3-1 | .750 | FTX Arena · Miami, FL |
| 5 | Fri Oct 9 | vsHeat | L108-111 | 3-2 | .600 | Crypto.com Arena · Los Angeles, CA |
| 6 | Sun Oct 11 | atHeat | W106-93 | 4-2 | .667 | FTX Arena · Miami, FL |
