| 1 | Tue Nov 9 | vs Louisiana Tech | W93-64 | 1-0 | 1.000 | #14 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 2 | Fri Nov 12 | vsS Dakota St | W104-88 | 2-0 | 1.000 | #14 | | Coleman Coliseum · Tuscaloosa, AL |
| 3 | Tue Nov 16 | vsSouth Alabama | W73-68 | 3-0 | 1.000 | #14 | | Coleman Coliseum · Tuscaloosa, AL |
| 4 | Fri Nov 19 | vsOakland | W86-59 | 4-0 | 1.000 | #14 | | Coleman Coliseum · Tuscaloosa, AL |
| 5 | Thu Nov 25 | atIona | L68-72 | 4-1 | .800 | - | ESPN2 | Hynes Athletics Center · New Rochelle, NY |
| 6 | Fri Nov 26 | atDrake | W80-71 | 5-1 | .833 | - | ESPNU | The Knapp Center · Des Moines, IA |
| 7 | Sun Nov 28 | vsMiami | W96-64 | 6-1 | .857 | - | ESPNU | Coleman Coliseum · Tuscaloosa, AL |
| 8 | Sat Dec 4 | atGonzaga | W91-82 | 7-1 | .875 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 9 | Sat Dec 11 | vs#14Houston | W83-82 | 8-1 | .889 | #9 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 10 | Tue Dec 14 | atMemphis | L78-92 | 8-2 | .800 | #6 | ESPN | FedExForum · Memphis, TN |
| 11 | Sat Dec 18 | vsJ'Ville St | W65-59 | 9-2 | .818 | #6 | | Coleman Coliseum · Tuscaloosa, AL |
| 12 | Tue Dec 21 | vsDavidson | L78-79 | 9-3 | .750 | #10 | | Coleman Coliseum · Tuscaloosa, AL |
| 13 | Wed Dec 29 | vs#14Tennessee | W73-68 | 10-3 | .769 | #19 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 14 | Wed Jan 5 | atFlorida | W83-70 | 11-3 | .786 | #15 | ESPN2 | O'Connell Center · Gainesville, FL |
| 15 | Sat Jan 8 | atMissouri | L86-92 | 11-4 | .733 | #15 | SEC Network | Mizzou Arena · Columbia, MO |
| 16 | Tue Jan 11 | vs#4Auburn | L77-81 | 11-5 | .688 | #24 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 17 | Sat Jan 15 | atMississippi St | L76-78 | 11-6 | .647 | #24 | SEC Network | Humphrey Coliseum · Starkville, MS |
| 18 | Wed Jan 19 | vs#13LSU | W70-67 | 12-6 | .667 | - | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 19 | Sat Jan 22 | vsMissouri | W86-76 | 13-6 | .684 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 20 | Tue Jan 25 | atGeorgia | L76-82 | 13-7 | .650 | - | SEC Network | Stegeman Coliseum · Athens, GA |
| 21 | Sat Jan 29 | vsBaylor | W87-78 | 14-7 | .667 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 22 | Tue Feb 1 | at#1Auburn | L81-100 | 14-8 | .636 | - | ESPN | Neville Arena · Auburn, AL |
| 23 | Sat Feb 5 | vs#5Kentucky | L55-66 | 14-9 | .609 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 24 | Wed Feb 9 | atOle Miss | W97-83 | 15-9 | .625 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 25 | Sat Feb 12 | vsArkansas | W68-67 | 16-9 | .640 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 26 | Wed Feb 16 | vsMississippi St | W80-75 | 17-9 | .654 | #25 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 27 | Sat Feb 19 | at#4Kentucky | L81-90 | 17-10 | .630 | #25 | CBS | Rupp Arena · Lexington, KY |
| 28 | Tue Feb 22 | atVanderbilt | W74-72 | 18-10 | .643 | #24 | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 29 | Sat Feb 26 | vsSouth Carolina | W90-71 | 19-10 | .655 | #24 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 30 | Wed Mar 2 | vsTexas A&M | L71-87 | 19-11 | .633 | #25 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 31 | Sat Mar 5 | atLSU | L77-80 (OT) | 19-12 | .613 | #25 | CBS | Pete Maravich Assembly Center · Baton Rouge, LA |
| 32 | Thu Mar 10 | vsVanderbilt | L76-82 | 19-13 | .594 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 33 | Fri Mar 18 | vs#11Notre Dame | L64-78 | 19-14 | .576 | #6 | TNT | Viejas Arena · San Diego, CA |
