| 1 | Mon Nov 6 | vs Morehead St | W105-73 | 1-0 | 1.000 | #24 | | Coleman Coliseum · Tuscaloosa, AL |
| 2 | Fri Nov 10 | vsIndiana St | W102-80 | 2-0 | 1.000 | #24 | | Coleman Coliseum · Tuscaloosa, AL |
| 3 | Tue Nov 14 | vsSouth Alabama | W102-46 | 3-0 | 1.000 | #22 | | Coleman Coliseum · Tuscaloosa, AL |
| 4 | Fri Nov 17 | vsMercer | W98-67 | 4-0 | 1.000 | #22 | | Coleman Coliseum · Tuscaloosa, AL |
| 5 | Fri Nov 24 | atOhio State | L81-92 | 4-1 | .800 | #17 | CBS | Value City Arena · Columbus, OH |
| 6 | Sat Nov 25 | atOregon | W99-91 | 5-1 | .833 | #17 | | Matthew Knight Arena · Eugene, OR |
| 7 | Tue Nov 28 | vsClemson | L77-85 | 5-2 | .714 | #23 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 8 | Mon Dec 4 | vsArkansas St | W89-65 | 6-2 | .750 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 9 | Sat Dec 9 | at#4Purdue | L86-92 | 6-3 | .667 | - | FOX | Mackey Arena · West Lafayette, IN |
| 10 | Sat Dec 16 | at#8Creighton | L82-85 | 6-4 | .600 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 11 | Wed Dec 20 | at#4Arizona | L74-87 | 6-5 | .545 | - | ESPN | McKale Center · Tucson, AZ |
| 12 | Sat Dec 23 | vsE Kentucky | W111-67 | 7-5 | .583 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 13 | Sat Dec 30 | vsLiberty | W101-56 | 8-5 | .615 | - | | Coleman Coliseum · Tuscaloosa, AL |
| 14 | Sat Jan 6 | atVanderbilt | W78-75 | 9-5 | .643 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 15 | Tue Jan 9 | vsSouth Carolina | W74-47 | 10-5 | .667 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 16 | Sat Jan 13 | atMississippi St | W82-74 | 11-5 | .688 | - | SEC Network | Humphrey Coliseum · Starkville, MS |
| 17 | Tue Jan 16 | vsMissouri | W93-75 | 12-5 | .706 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 18 | Sat Jan 20 | at#6Tennessee | L71-91 | 12-6 | .667 | - | ESPN2 | Thompson-Boling Arena · Knoxville, TN |
| 19 | Wed Jan 24 | vs#8Auburn | W79-75 | 13-6 | .684 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 20 | Sat Jan 27 | vsLSU | W109-88 | 14-6 | .700 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 21 | Wed Jan 31 | atGeorgia | W85-76 | 15-6 | .714 | #24 | SEC Network | Stegeman Coliseum · Athens, GA |
| 22 | Sat Feb 3 | vsMississippi St | W99-67 | 16-6 | .727 | #24 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 23 | Wed Feb 7 | at#12Auburn | L81-99 | 16-7 | .696 | #16 | ESPN2 | Neville Arena · Auburn, AL |
| 24 | Sat Feb 10 | atLSU | W109-92 | 17-7 | .708 | #16 | ESPN | Pete Maravich Assembly Center · Baton Rouge, LA |
| 25 | Sat Feb 17 | vsTexas A&M | W100-75 | 18-7 | .720 | #15 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 26 | Wed Feb 21 | vs#24Florida | W98-93 (OT) | 19-7 | .731 | #13 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 27 | Sat Feb 24 | at#17Kentucky | L95-117 | 19-8 | .704 | #13 | CBS | Rupp Arena · Lexington, KY |
| 28 | Wed Feb 28 | atOle Miss | W103-88 | 20-8 | .714 | #14 | ESPN2 | SJB Pavilion · Oxford, MS |
| 29 | Sat Mar 2 | vs#4Tennessee | L74-81 | 20-9 | .690 | #14 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 30 | Tue Mar 5 | atFlorida | L87-105 | 20-10 | .667 | #16 | ESPN | O'Connell Center · Gainesville, FL |
| 31 | Sat Mar 9 | vsArkansas | W92-88 (OT) | 21-10 | .677 | #16 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 32 | Fri Mar 15 | vsFlorida | L88-102 | 21-11 | .656 | #19 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 33 | Fri Mar 22 | vs#13Charleston | W109-96 | 22-11 | .667 | #4 | truTV | Coleman Coliseum · Tuscaloosa, AL |
| 34 | Sun Mar 24 | vs#12Grand Canyon | W72-61 | 23-11 | .676 | #4 | TBS | Coleman Coliseum · Tuscaloosa, AL |
| 35 | Thu Mar 28 | at#1UNC | W89-87 | 24-11 | .686 | #4 | CBS | Dean E. Smith Center · Chapel Hill, NC |
| 36 | Sat Mar 30 | vs#6Clemson | W89-82 | 25-11 | .694 | #4 | TBS | Coleman Coliseum · Tuscaloosa, AL |
| 37 | Sat Apr 6 | at#1UConn | L72-86 | 25-12 | .676 | #4 | TBS | Gampel Pavilion · Storrs, CT |
