| 1 | Mon Nov 7 | vs Longwood | W75-54 | 1-0 | 1.000 | #20 | | Coleman Coliseum · Tuscaloosa, AL |
| 2 | Fri Nov 11 | vsLiberty | W95-59 | 2-0 | 1.000 | #20 | | Coleman Coliseum · Tuscaloosa, AL |
| 3 | Tue Nov 15 | atSouth Alabama | W65-55 | 3-0 | 1.000 | #18 | ESPNU | Mitchell Center · Mobile, AL |
| 4 | Fri Nov 18 | vsJ'Ville St | W104-62 | 4-0 | 1.000 | #18 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 5 | Thu Nov 24 | atMichigan St | W81-70 | 5-0 | 1.000 | - | ESPN | Breslin Center · East Lansing, MI |
| 6 | Fri Nov 25 | vsUConn | L67-82 | 5-1 | .833 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 7 | Sun Nov 27 | vsUNC | W103-101 (4OT) | 6-1 | .857 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 8 | Sat Dec 3 | vsS Dakota St | W78-65 | 7-1 | .875 | #11 | | Coleman Coliseum · Tuscaloosa, AL |
| 9 | Sat Dec 10 | at#1Houston | W71-65 | 8-1 | .889 | #8 | ABC | Fertitta Center · Houston, TX |
| 10 | Tue Dec 13 | vsMemphis | W91-88 | 9-1 | .900 | #4 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 11 | Sat Dec 17 | vsGonzaga | L90-100 | 9-2 | .818 | - | CBS | Coleman Coliseum · Tuscaloosa, AL |
| 12 | Tue Dec 20 | vsJackson St | W84-64 | 10-2 | .833 | #9 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 13 | Wed Dec 28 | at#21Mississippi St | W78-67 | 11-2 | .846 | #8 | SEC Network | Humphrey Coliseum · Starkville, MS |
| 14 | Tue Jan 3 | vsOle Miss | W84-62 | 12-2 | .857 | #7 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 15 | Sat Jan 7 | vsKentucky | W78-52 | 13-2 | .867 | #7 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 16 | Wed Jan 11 | at#15Arkansas | W84-69 | 14-2 | .875 | #4 | ESPN2 | Bud Walton Arena · Fayetteville, AR |
| 17 | Sat Jan 14 | vsLSU | W106-66 | 15-2 | .882 | #4 | ESPNEWS | Coleman Coliseum · Tuscaloosa, AL |
| 18 | Tue Jan 17 | atVanderbilt | W78-66 | 16-2 | .889 | #4 | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 19 | Sat Jan 21 | atMissouri | W85-64 | 17-2 | .895 | #4 | SEC Network | Mizzou Arena · Columbia, MO |
| 20 | Wed Jan 25 | vsMississippi St | W66-63 | 18-2 | .900 | #2 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 21 | Sat Jan 28 | atOklahoma | L69-93 | 18-3 | .857 | - | ESPN | Lloyd Noble Center · Norman, OK |
| 22 | Tue Jan 31 | vsVanderbilt | W101-44 | 19-3 | .864 | #4 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 23 | Sat Feb 4 | atLSU | W79-69 | 20-3 | .870 | #4 | ESPNU | Pete Maravich Assembly Center · Baton Rouge, LA |
| 24 | Wed Feb 8 | vsFlorida | W97-69 | 21-3 | .875 | #3 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 25 | Sat Feb 11 | atAuburn | W77-69 | 22-3 | .880 | #3 | ESPN | Neville Arena · Auburn, AL |
| 26 | Wed Feb 15 | at#10Tennessee | L59-68 | 22-4 | .846 | #1 | ESPN2 | Thompson-Boling Arena · Knoxville, TN |
| 27 | Sat Feb 18 | vsGeorgia | W108-59 | 23-4 | .852 | #1 | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 28 | Wed Feb 22 | atSouth Carolina | W78-76 (OT) | 24-4 | .857 | #2 | ESPN2 | Colonial Life Arena · Columbia, SC |
| 29 | Sat Feb 25 | vsArkansas | W86-83 | 25-4 | .862 | #2 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 30 | Wed Mar 1 | vsAuburn | W90-85 (OT) | 26-4 | .867 | #2 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 31 | Sat Mar 4 | at#24Texas A&M | L61-67 | 26-5 | .839 | #2 | CBS | Reed Arena · College Station, TX |
| 32 | Fri Mar 10 | vsMississippi St | W72-49 | 27-5 | .844 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 33 | Sat Mar 11 | vsMissouri | W72-61 | 28-5 | .848 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 34 | Sun Mar 12 | vsTexas A&M | W82-63 | 29-5 | .853 | - | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 35 | Thu Mar 16 | vs#16Texas A&M-CC | W96-75 | 30-5 | .857 | #1 | CBS | Coleman Coliseum · Tuscaloosa, AL |
| 36 | Sat Mar 18 | vs#8Maryland | W73-51 | 31-5 | .861 | #1 | TBS | Coleman Coliseum · Tuscaloosa, AL |
| 37 | Fri Mar 24 | vs#5SDSU | L64-71 | 31-6 | .838 | #1 | TBS | Coleman Coliseum · Tuscaloosa, AL |
