| 1 | Mon Nov 4 | vs Presbyterian | W88-79 | 1-0 | 1.000 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 2 | Sat Nov 9 | atUtah State | L74-103 | 1-1 | .500 | - | | Dee Glen Smith Spectrum · Logan, UT |
| 3 | Wed Nov 13 | vsRichmond | W65-48 | 2-1 | .667 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 4 | Tue Nov 19 | vsGardner-Webb | W60-54 | 3-1 | .750 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 5 | Sat Nov 23 | vsLong Island | L76-79 | 3-2 | .600 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 6 | Wed Nov 27 | vsETSU | L55-75 | 3-3 | .500 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 7 | Wed Dec 4 | vsTBD | W83-61 | 4-3 | .571 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 8 | Tue Dec 10 | atDavidson | L71-75 | 4-4 | .500 | - | ESPN+ | John M. Belk Arena · Davidson, NC |
| 9 | Sat Dec 14 | atGeorgia St | W77-63 | 5-4 | .556 | - | ESPN+ | GSU Convocation Center · Atlanta, GA |
| 10 | Tue Dec 17 | vsW Georgia | W75-70 | 6-4 | .600 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 11 | Sun Dec 22 | atHawai'i | L61-78 | 6-5 | .545 | - | ESPN2 | Stan Sheriff Center · Honolulu, HI |
| 12 | Tue Dec 24 | vsMurray St | W94-90 (2OT) | 7-5 | .583 | - | ESPN2 | Stan Sheriff Center · Honolulu, HI |
| 13 | Wed Dec 25 | vsCharleston | L81-84 | 7-6 | .538 | - | ESPNU | Stan Sheriff Center · Honolulu, HI |
| 14 | Tue Dec 31 | vsTulane | L68-83 | 7-7 | .500 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 15 | Sat Jan 4 | atRice | L55-68 | 7-8 | .467 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 16 | Wed Jan 8 | vsFAU | L64-75 | 7-9 | .438 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 17 | Sun Jan 12 | atTulsa | L63-69 | 7-10 | .412 | - | ESPN+ | Donald W. Reynolds Center · Tulsa, OK |
| 18 | Tue Jan 14 | atWichita St | L59-68 | 7-11 | .389 | - | ESPN+ | Charles Koch Arena · Wichita, KS |
| 19 | Sun Jan 19 | vs18Memphis | L68-77 | 7-12 | .368 | - | ESPN2 | Dale F. Halton Arena · Charlotte, NC |
| 20 | Wed Jan 22 | vsSouth Florida | W69-61 | 8-12 | .400 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 21 | Wed Jan 29 | atTemple | L89-90 (2OT) | 8-13 | .381 | - | ESPN+ | Liacouras Center · Philadelphia, PA |
| 22 | Sat Feb 1 | atUAB | L78-96 | 8-14 | .364 | - | ESPN+ | Bartow Arena · Birmingham, AL |
| 23 | Tue Feb 4 | vsWichita St | L58-66 | 8-15 | .348 | - | ESPNU | Dale F. Halton Arena · Charlotte, NC |
| 24 | Sat Feb 8 | vsRice | W78-75 | 9-15 | .375 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 25 | Mon Feb 10 | atFAU | L75-87 | 9-16 | .360 | - | ESPN2 | FAU Arena · Boca Raton, FL |
| 26 | Sat Feb 15 | vsE Carolina | L59-75 | 9-17 | .346 | - | ESPNEWS | Dale F. Halton Arena · Charlotte, NC |
| 27 | Wed Feb 19 | vsTemple | W78-72 (OT) | 10-17 | .370 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 28 | Wed Feb 26 | atTulane | L64-78 | 10-18 | .357 | - | ESPN+ | Devlin Fieldhouse · New Orleans, LA |
| 29 | Sun Mar 2 | atE Carolina | L76-78 | 10-19 | .345 | - | ESPNU | Williams Arena at Minges Coliseum · Greenville, NC |
| 30 | Thu Mar 6 | atNorth Texas | L64-75 | 10-20 | .333 | - | ESPN2 | The Super Pit · Denton, TX |
| 31 | Sun Mar 9 | vsUTSA | L80-83 | 10-21 | .323 | - | ESPN+ | Dale F. Halton Arena · Charlotte, NC |
| 32 | Wed Mar 12 | atRice | W64-61 | 11-21 | .344 | - | ESPN+ | The Super Pit · Denton, TX |
| 33 | Thu Mar 13 | atFAU | L59-64 | 11-22 | .333 | - | ESPNU | FAU Arena · Boca Raton, FL |
