| 1 | Tue Nov 9 | at Butler | L47-56 | 0-1 | .000 | - | | Hinkle Fieldhouse · Indianapolis, IN |
| 2 | Thu Nov 11 | atEvansville | L40-60 | 0-2 | .000 | - | | Ford Center · Evansville, IN |
| 3 | Mon Nov 15 | atDenver | L47-63 | 0-3 | .000 | - | | UTSA Convocation Center · San Antonio, TX |
| 4 | Tue Nov 16 | atTexas A&M-CC | L59-65 | 0-4 | .000 | - | | UTSA Convocation Center · San Antonio, TX |
| 5 | Wed Nov 17 | atUTSA | L57-60 | 0-5 | .000 | - | | UTSA Convocation Center · San Antonio, TX |
| 6 | Tue Nov 23 | vsTBD | W61-41 | 1-5 | .167 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 7 | Thu Dec 2 | vsDetroit Mercy | L45-69 | 1-6 | .143 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 8 | Sat Dec 4 | vsOakland | L45-78 | 1-7 | .125 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 9 | Fri Dec 10 | atTennessee St | L44-70 | 1-8 | .111 | - | | Gentry Center · Nashville, TN |
| 10 | Thu Dec 16 | vsChicago St | L55-61 | 1-9 | .100 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 11 | Tue Dec 21 | vsMorehead St | L52-80 | 1-10 | .091 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 14 | Sat Jan 8 | atWright St | L58-72 | 1-11 | .083 | - | | Nutter Center · Dayton, OH |
| 15 | Mon Jan 10 | vsUIC | L65-67 | 1-12 | .077 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 16 | Thu Jan 13 | atGreen Bay | L54-69 | 1-13 | .071 | - | | Resch Center · Ashwaubenon, WI |
| 17 | Sat Jan 15 | atMilwaukee | L54-89 | 1-14 | .067 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 18 | Tue Jan 18 | at19Ohio State | L37-83 | 1-15 | .063 | - | BTN | Value City Arena · Columbus, OH |
| 19 | Thu Jan 20 | vsWright St | L45-73 | 1-16 | .059 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 20 | Sat Jan 22 | vsN Kentucky | L41-60 | 1-17 | .056 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 23 | Mon Jan 31 | vsTBD | W75-59 | 2-17 | .105 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 24 | Thu Feb 3 | vsYoungstown St | L55-61 | 2-18 | .100 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 25 | Sat Feb 5 | vsRobert Morris | L49-66 | 2-19 | .095 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 26 | Thu Feb 10 | atPurdue FW | L57-72 | 2-20 | .091 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 27 | Sat Feb 12 | atCleveland St | L45-83 | 2-21 | .087 | - | | Wolstein Center · Cleveland, OH |
| 28 | Mon Feb 14 | atUIC | L54-57 | 2-22 | .083 | - | | Credit Union 1 Arena · Chicago, IL |
| 29 | Thu Feb 17 | atRobert Morris | W66-56 | 3-22 | .120 | - | | UPMC Events Center · Moon Township, PA |
| 30 | Sat Feb 19 | atYoungstown St | L61-74 | 3-23 | .115 | - | | Beeghly Center · Youngstown, OH |
| 31 | Thu Feb 24 | vsMilwaukee | L54-66 | 3-24 | .111 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 32 | Sat Feb 26 | vsGreen Bay | L41-67 | 3-25 | .107 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 33 | Tue Mar 1 | atOakland | L58-70 | 3-26 | .103 | - | | Athletics Center O'rena · Rochester, MI |
