| 1 | Sun Sep 8 | vs Falcons | W28-12 | 1-0 | 1.000 | U.S. Bank Stadium · Minneapolis, MN |
| 2 | Sun Sep 15 | at Packers | L16-21 | 1-1 | .500 | Lambeau Field · Green Bay, WI |
| 3 | Sun Sep 22 | vs Raiders | W34-14 | 2-1 | .667 | U.S. Bank Stadium · Minneapolis, MN |
| 4 | Sun Sep 29 | at Bears | L6-16 | 2-2 | .500 | Soldier Field · Chicago, IL |
| 5 | Sun Oct 6 | at Giants | W28-10 | 3-2 | .600 | MetLife Stadium · East Rutherford, NJ |
| 6 | Sun Oct 13 | vs Eagles | W38-20 | 4-2 | .667 | U.S. Bank Stadium · Minneapolis, MN |
| 7 | Sun Oct 20 | at Lions | W42-30 | 5-2 | .714 | Ford Field · Detroit, MI |
| 8 | Thu Oct 24 | vs Commanders | W19-9 | 6-2 | .750 | U.S. Bank Stadium · Minneapolis, MN |
| 9 | Sun Nov 3 | at Chiefs | L23-26 | 6-3 | .667 | Arrowhead Stadium · Kansas City, MO |
| 10 | Sun Nov 10 | at Cowboys | W28-24 | 7-3 | .700 | AT&T Stadium · Arlington, TX |
| 11 | Sun Nov 17 | vs Broncos | W27-23 | 8-3 | .727 | U.S. Bank Stadium · Minneapolis, MN |
| 12 | -- BYE WEEK -- |
| 13 | Mon Dec 2 | at Seahawks | L30-37 | 8-4 | .667 | Lumen Field · Seattle, WA |
| 14 | Sun Dec 8 | vsLions | W20-7 | 9-4 | .692 | U.S. Bank Stadium · Minneapolis, MN |
| 15 | Sun Dec 15 | at Chargers | W39-10 | 10-4 | .714 | SoFi Stadium · Inglewood, CA |
| 16 | Mon Dec 23 | vsPackers | L10-23 | 10-5 | .667 | U.S. Bank Stadium · Minneapolis, MN |
| 17 | Sun Dec 29 | vsBears | L19-21 | 10-6 | .625 | U.S. Bank Stadium · Minneapolis, MN |
| WC | Sun Jan 5 | at Saints | W26-20 (OT) | 10-6 | .625 | Caesars Superdome · New Orleans, LA |
| DIV | Sat Jan 11 | at 49ers | L10-27 | 10-6 | .625 | Levi's® Stadium · Santa Clara, CA |
