| 1 | Mon Nov 7 | vs TBD | W87-64 | 1-0 | 1.000 | - | | John M. Belk Arena · Davidson, NC |
| 2 | Wed Nov 9 | at Wright St | W102-97 (2OT) | 2-0 | 1.000 | - | | Nutter Center · Dayton, OH |
| 3 | Sun Nov 13 | vs VMI | W75-71 | 3-0 | 1.000 | - | | John M. Belk Arena · Davidson, NC |
| 4 | Thu Nov 17 | at Charleston | L66-89 | 3-1 | .750 | - | ESPNU | TD Arena · Charleston, SC |
| 5 | Fri Nov 18 | vs South Carolina | W69-60 | 4-1 | .800 | - | ESPNEWS | John M. Belk Arena · Davidson, NC |
| 6 | Sun Nov 20 | vs Old Dominion | W66-61 | 5-1 | .833 | - | ESPNEWS | John M. Belk Arena · Davidson, NC |
| 7 | Fri Nov 25 | vs San Francisco | W89-80 | 6-1 | .857 | - | | John M. Belk Arena · Davidson, NC |
| 8 | Tue Nov 29 | vs Charlotte | L66-68 (OT) | 6-2 | .750 | - | | John M. Belk Arena · Davidson, NC |
| 9 | Sat Dec 3 | at Delaware | L67-69 | 6-3 | .667 | - | | Bob Carpenter Center · Newark, DE |
| 10 | Wed Dec 7 | vs W Carolina | W72-64 | 7-3 | .700 | - | | John M. Belk Arena · Davidson, NC |
| 11 | Sat Dec 17 | at Purdue | L61-69 | 7-4 | .636 | - | BTN | Mackey Arena · West Lafayette, IN |
| 12 | Wed Dec 21 | vs Northeastern | L70-73 | 7-5 | .583 | - | | John M. Belk Arena · Davidson, NC |
| 13 | Wed Dec 28 | at Fordham | W57-43 | 8-5 | .615 | - | CBS | Rose Hill Gymnasium · Bronx, NY |
| 14 | Sat Dec 31 | vs Dayton | L55-69 | 8-6 | .571 | - | | John M. Belk Arena · Davidson, NC |
| 15 | Wed Jan 4 | vs Loyola Chicago | W80-57 | 9-6 | .600 | - | CBS | John M. Belk Arena · Davidson, NC |
| 16 | Sat Jan 7 | at VCU | L72-89 | 9-7 | .563 | - | USA Net | Stuart C. Siegel Center · Richmond, VA |
| 17 | Wed Jan 11 | vs Richmond | L57-61 | 9-8 | .529 | - | | John M. Belk Arena · Davidson, NC |
| 18 | Sat Jan 14 | at George Mason | L65-67 | 9-9 | .500 | - | ESPNU | EagleBank Arena · Fairfax, VA |
| 19 | Tue Jan 17 | atDayton | L61-68 | 9-10 | .474 | - | CBS | UD Arena · Dayton, OH |
| 20 | Tue Jan 24 | at La Salle | W64-57 | 10-10 | .500 | - | | Tom Gola Arena · Philadelphia, PA |
| 21 | Fri Jan 27 | vs Saint Louis | L70-74 | 10-11 | .476 | - | ESPN2 | John M. Belk Arena · Davidson, NC |
| 22 | Tue Jan 31 | vsVCU | L59-61 | 10-12 | .455 | - | CBS | John M. Belk Arena · Davidson, NC |
| 23 | Sat Feb 4 | at UMass | W93-78 | 11-12 | .478 | - | USA Net | William D. Mullins Memorial Center · Amherst, MA |
| 24 | Sat Feb 11 | vsFordham | L71-73 | 11-13 | .458 | - | USA Net | John M. Belk Arena · Davidson, NC |
| 25 | Wed Feb 15 | atSaint Louis | L65-78 | 11-14 | .440 | - | CBS | Chaifetz Arena · St. Louis, MO |
| 26 | Sat Feb 18 | vs Saint Joseph's | W76-75 | 12-14 | .462 | - | USA Net | John M. Belk Arena · Davidson, NC |
| 27 | Wed Feb 22 | vs St Bonaventure | W74-61 | 13-14 | .481 | - | | John M. Belk Arena · Davidson, NC |
| 28 | Sun Feb 26 | at Duquesne | W71-67 | 14-14 | .500 | - | USA Net | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 29 | Wed Mar 1 | vs G Washington | L70-75 | 14-15 | .483 | - | | John M. Belk Arena · Davidson, NC |
| 30 | Sat Mar 4 | at Rhode Island | W68-54 | 15-15 | .500 | - | CBS | Ryan Center · Kingston, RI |
| 31 | Wed Mar 8 | vsSt Bonaventure | W65-54 | 16-15 | .516 | - | USA Net | John M. Belk Arena · Davidson, NC |
| 32 | Thu Mar 9 | atVCU | L53-71 | 16-16 | .500 | - | USA Net | Stuart C. Siegel Center · Richmond, VA |
