| 1 | Wed Oct 20 | vs Bulls | L88-94 | 0-1 | .000 | Little Caesars Arena · Detroit, MI |
| 2 | Sat Oct 23 | atBulls | L82-97 | 0-2 | .000 | United Center · Chicago, IL |
| 3 | Mon Oct 25 | at Hawks | L104-122 | 0-3 | .000 | State Farm Arena · Atlanta, GA |
| 4 | Thu Oct 28 | at 76ers | L102-110 | 0-4 | .000 | Wells Fargo Center · Philadelphia, PA |
| 5 | Sat Oct 30 | vs Magic | W110-103 | 1-4 | .200 | Little Caesars Arena · Detroit, MI |
| 6 | Sun Oct 31 | at Nets | L91-117 | 1-5 | .167 | Barclays Center · Brooklyn, NY |
| 7 | Tue Nov 2 | vs Bucks | L89-117 | 1-6 | .143 | Little Caesars Arena · Detroit, MI |
| 8 | Thu Nov 4 | vs76ers | L98-109 | 1-7 | .125 | Little Caesars Arena · Detroit, MI |
| 9 | Fri Nov 5 | vsNets | L90-96 | 1-8 | .111 | Little Caesars Arena · Detroit, MI |
| 10 | Wed Nov 10 | at Rockets | W112-104 | 2-8 | .200 | Toyota Center · Houston, TX |
| 11 | Fri Nov 12 | at Cavaliers | L78-98 | 2-9 | .182 | Rocket Mortgage FieldHouse · Cleveland, OH |
| 12 | Sat Nov 13 | at Raptors | W127-121 | 3-9 | .250 | Scotiabank Arena · Toronto, ON |
| 13 | Mon Nov 15 | vs Kings | L107-129 | 3-10 | .231 | Little Caesars Arena · Detroit, MI |
| 14 | Wed Nov 17 | vs Pacers | W97-89 | 4-10 | .286 | Little Caesars Arena · Detroit, MI |
| 15 | Fri Nov 19 | vs Warriors | L102-105 | 4-11 | .267 | Little Caesars Arena · Detroit, MI |
| 16 | Sun Nov 21 | vs Lakers | L116-121 | 4-12 | .250 | Little Caesars Arena · Detroit, MI |
| 17 | Tue Nov 23 | vs Heat | L92-100 | 4-13 | .235 | Little Caesars Arena · Detroit, MI |
| 18 | Wed Nov 24 | atBucks | L93-114 | 4-14 | .222 | Fiserv Forum · Milwaukee, WI |
| 19 | Fri Nov 26 | at Clippers | L96-107 | 4-15 | .211 | Crypto.com Arena · Los Angeles, CA |
| 20 | Sun Nov 28 | atLakers | L106-110 | 4-16 | .200 | Crypto.com Arena · Los Angeles, CA |
| 21 | Tue Nov 30 | at Blazers | L92-110 | 4-17 | .190 | Moda Center · Portland, OR |
| 22 | Thu Dec 2 | at Suns | L103-114 | 4-18 | .182 | Footprint Center · Phoenix, AZ |
| 23 | Mon Dec 6 | vs Thunder | L103-114 | 4-19 | .174 | Little Caesars Arena · Detroit, MI |
| 24 | Wed Dec 8 | vs Wizards | L116-119 (OT) | 4-20 | .167 | Little Caesars Arena · Detroit, MI |
| 25 | Fri Dec 10 | at Pelicans | L93-109 | 4-21 | .160 | Smoothie King Center · New Orleans, LA |
| 26 | Sun Dec 12 | vsNets | L104-116 | 4-22 | .154 | Little Caesars Arena · Detroit, MI |
| 27 | Thu Dec 16 | atPacers | L113-122 | 4-23 | .148 | Gainbridge Fieldhouse · Indianapolis, IN |
| 28 | Sat Dec 18 | vsRockets | L107-116 | 4-24 | .143 | Little Caesars Arena · Detroit, MI |
| 29 | Sun Dec 19 | vsHeat | W100-90 | 5-24 | .172 | Little Caesars Arena · Detroit, MI |
| 30 | Tue Dec 21 | at Knicks | L91-105 | 5-25 | .167 | Madison Square Garden · Manhattan, NY |
| 31 | Thu Dec 23 | atHeat | L112-115 | 5-26 | .161 | FTX Arena · Miami, FL |
| 32 | Sun Dec 26 | at Spurs | L109-144 | 5-27 | .156 | AT&T Center · San Antonio, TX |
| 33 | Wed Dec 29 | vsKnicks | L85-94 | 5-28 | .152 | Little Caesars Arena · Detroit, MI |
| 34 | Sat Jan 1 | vsSpurs | W117-116 (OT) | 6-28 | .176 | Little Caesars Arena · Detroit, MI |
| 35 | Mon Jan 3 | atBucks | W115-106 | 7-28 | .200 | Fiserv Forum · Milwaukee, WI |
| 36 | Wed Jan 5 | at Hornets | L111-140 | 7-29 | .194 | Spectrum Center · Charlotte, NC |
| 37 | Thu Jan 6 | at Grizzlies | L88-118 | 7-30 | .189 | FedExForum · Memphis, TN |
| 38 | Sat Jan 8 | vsMagic | W97-92 | 8-30 | .211 | Little Caesars Arena · Detroit, MI |
| 39 | Mon Jan 10 | vs Jazz | W126-116 | 9-30 | .231 | Little Caesars Arena · Detroit, MI |
| 40 | Tue Jan 11 | atBulls | L87-133 | 9-31 | .225 | United Center · Chicago, IL |
| 41 | Fri Jan 14 | vsRaptors | W103-87 | 10-31 | .244 | Little Caesars Arena · Detroit, MI |
| 42 | Sun Jan 16 | vsSuns | L108-135 | 10-32 | .238 | Little Caesars Arena · Detroit, MI |
| 43 | Tue Jan 18 | atWarriors | L86-102 | 10-33 | .233 | Chase Center · San Francisco, CA |
| 44 | Wed Jan 19 | atKings | W133-131 | 11-33 | .250 | Golden 1 Center · Sacramento, CA |
| 45 | Fri Jan 21 | atJazz | L101-111 | 11-34 | .244 | Vivint Arena · Salt Lake City, UT |
| 46 | Sun Jan 23 | at Nuggets | L111-117 | 11-35 | .239 | Ball Arena · Denver, CO |
| 47 | Tue Jan 25 | vsNuggets | L105-110 | 11-36 | .234 | Little Caesars Arena · Detroit, MI |
| 48 | Fri Jan 28 | atMagic | L103-119 | 11-37 | .229 | Amway Center · Orlando, FL |
| 49 | Sun Jan 30 | vsCavaliers | W115-105 | 12-37 | .245 | Little Caesars Arena · Detroit, MI |
| 50 | Tue Feb 1 | vsPelicans | L101-111 | 12-38 | .240 | Little Caesars Arena · Detroit, MI |
| 51 | Thu Feb 3 | vs T-wolves | L117-128 | 12-39 | .235 | Little Caesars Arena · Detroit, MI |
| 52 | Fri Feb 4 | vs Celtics | L93-102 | 12-40 | .231 | Little Caesars Arena · Detroit, MI |
| 53 | Sun Feb 6 | atT-wolves | L105-118 | 12-41 | .226 | Target Center · Minneapolis, MN |
| 54 | Tue Feb 8 | at Mavericks | L86-116 | 12-42 | .222 | American Airlines Center · Dallas, TX |
| 55 | Thu Feb 10 | vsGrizzlies | L107-132 | 12-43 | .218 | Little Caesars Arena · Detroit, MI |
| 56 | Fri Feb 11 | vsHornets | L119-141 | 12-44 | .214 | Little Caesars Arena · Detroit, MI |
| 57 | Mon Feb 14 | atWizards | L94-103 | 12-45 | .211 | Capital One Arena · Washington, D.C. |
| 58 | Wed Feb 16 | atCeltics | W112-111 | 13-45 | .224 | TD Garden · Boston, MA |
| 59 | Thu Feb 24 | vsCavaliers | W106-103 | 14-45 | .237 | Little Caesars Arena · Detroit, MI |
| 60 | Sat Feb 26 | vsCeltics | L104-113 | 14-46 | .233 | Little Caesars Arena · Detroit, MI |
| 61 | Sun Feb 27 | atHornets | W127-126 (OT) | 15-46 | .246 | Spectrum Center · Charlotte, NC |
| 62 | Tue Mar 1 | atWizards | L113-116 | 15-47 | .242 | Capital One Arena · Washington, D.C. |
| 63 | Thu Mar 3 | atRaptors | W108-106 | 16-47 | .254 | Scotiabank Arena · Toronto, ON |
| 64 | Fri Mar 4 | vsPacers | W111-106 | 17-47 | .266 | Little Caesars Arena · Detroit, MI |
| 65 | Mon Mar 7 | vsHawks | W113-110 (OT) | 18-47 | .277 | Little Caesars Arena · Detroit, MI |
| 66 | Wed Mar 9 | vsBulls | L108-114 | 18-48 | .273 | Little Caesars Arena · Detroit, MI |
| 67 | Fri Mar 11 | atCeltics | L103-114 | 18-49 | .269 | TD Garden · Boston, MA |
| 68 | Sun Mar 13 | vsClippers | L102-106 | 18-50 | .265 | Little Caesars Arena · Detroit, MI |
| 69 | Tue Mar 15 | atHeat | L98-105 | 18-51 | .261 | FTX Arena · Miami, FL |
| 70 | Thu Mar 17 | atMagic | W134-120 | 19-51 | .271 | Amway Center · Orlando, FL |
| 71 | Sat Mar 19 | atCavaliers | L109-113 | 19-52 | .268 | Rocket Mortgage FieldHouse · Cleveland, OH |
| 72 | Mon Mar 21 | vsBlazers | L115-119 | 19-53 | .264 | Little Caesars Arena · Detroit, MI |
| 73 | Wed Mar 23 | vsHawks | W122-101 | 20-53 | .274 | Little Caesars Arena · Detroit, MI |
| 74 | Fri Mar 25 | vsWizards | L97-100 | 20-54 | .270 | Little Caesars Arena · Detroit, MI |
| 75 | Sun Mar 27 | vsKnicks | L102-104 | 20-55 | .267 | Little Caesars Arena · Detroit, MI |
| 76 | Tue Mar 29 | atNets | L123-130 | 20-56 | .263 | Barclays Center · Brooklyn, NY |
| 77 | Thu Mar 31 | vs76ers | W102-94 | 21-56 | .273 | Little Caesars Arena · Detroit, MI |
| 78 | Fri Apr 1 | atThunder | W110-101 | 22-56 | .282 | Paycom Center · Oklahoma City, OK |
| 79 | Sun Apr 3 | atPacers | W121-117 | 23-56 | .291 | Gainbridge Fieldhouse · Indianapolis, IN |
| 80 | Wed Apr 6 | vsMavericks | L113-131 | 23-57 | .287 | Little Caesars Arena · Detroit, MI |
| 81 | Fri Apr 8 | vsBucks | L101-131 | 23-58 | .284 | Little Caesars Arena · Detroit, MI |
| 82 | Sun Apr 10 | at76ers | L106-118 | 23-59 | .280 | Wells Fargo Center · Philadelphia, PA |
