| 1 | Wed Oct 22 | at Jazz | L108-129 | 0-1 | .000 | | Vivint Arena · Salt Lake City, UT |
| 2 | Fri Oct 24 | vs Suns | W129-102 | 1-1 | .500 | | Intuit Dome · Inglewood, CA |
| 3 | Sun Oct 26 | vs Blazers | W114-107 | 2-1 | .667 | | Intuit Dome · Inglewood, CA |
| 4 | Tue Oct 28 | at Warriors | L79-98 | 2-2 | .500 | Peacock | Chase Center · San Francisco, CA |
| 5 | Fri Oct 31 | vs Pelicans | W126-124 | 3-2 | .600 | | Intuit Dome · Inglewood, CA |
| 6 | Mon Nov 3 | vs Heat | L119-120 | 3-3 | .500 | | Intuit Dome · Inglewood, CA |
| 7 | Tue Nov 4 | vs Thunder | L107-126 | 3-4 | .429 | Peacock | Intuit Dome · Inglewood, CA |
| 8 | Thu Nov 6 | at Suns | L102-115 | 3-5 | .375 | NBA TV | Mortgage Matchup Center · Phoenix, AZ |
| 9 | Sat Nov 8 | vs Suns | L103-114 | 3-6 | .333 | ESPN | Intuit Dome · Inglewood, CA |
| 10 | Mon Nov 10 | vs Hawks | L102-105 | 3-7 | .300 | NBA TV | Intuit Dome · Inglewood, CA |
| 11 | Wed Nov 12 | vs Nuggets | L116-130 | 3-8 | .273 | | Intuit Dome · Inglewood, CA |
| 12 | Fri Nov 14 | at Mavericks | W133-127 (2OT) | 4-8 | .333 | | American Airlines Center · Dallas, TX |
| 13 | Sun Nov 16 | at Celtics | L118-121 | 4-9 | .308 | | TD Garden · Boston, MA |
| 14 | Mon Nov 17 | at 76ers | L108-110 | 4-10 | .286 | | Wells Fargo Center · Philadelphia, PA |
| 15 | Thu Nov 20 | at Magic | L101-129 | 4-11 | .267 | | Kia Center · Orlando, FL |
| 16 | Sat Nov 22 | at Hornets | W131-116 | 5-11 | .313 | | Spectrum Center · Charlotte, NC |
| 17 | Sun Nov 23 | at Cavaliers | L105-120 | 5-12 | .294 | | Rocket Mortgage FieldHouse · Cleveland, OH |
| 18 | Tue Nov 25 | at Lakers | L118-135 | 5-13 | .278 | Peacock | Crypto.com Arena · Los Angeles, CA |
| 19 | Fri Nov 28 | vs Grizzlies | L107-112 | 5-14 | .263 | | Intuit Dome · Inglewood, CA |
| 20 | Sat Nov 29 | vs Mavericks | L110-114 | 5-15 | .250 | | Intuit Dome · Inglewood, CA |
| 21 | Mon Dec 1 | at Heat | L123-140 | 5-16 | .238 | | Kaseya Center · Miami, FL |
| 22 | Wed Dec 3 | at Hawks | W115-92 | 6-16 | .273 | | State Farm Arena · Atlanta, GA |
| 23 | Fri Dec 5 | at Grizzlies | L98-107 | 6-17 | .261 | | FedExForum · Memphis, TN |
| 24 | Sat Dec 6 | at T-wolves | L106-109 | 6-18 | .250 | | Target Center · Minneapolis, MN |
| 25 | Thu Dec 11 | at Rockets | L113-115 | 6-19 | .240 | | Toyota Center · Houston, TX |
| 26 | Mon Dec 15 | vs Grizzlies | L103-121 | 6-20 | .231 | | Intuit Dome · Inglewood, CA |
| 27 | Thu Dec 18 | at Thunder | L101-122 | 6-21 | .222 | NBA TV | Paycom Center · Oklahoma City, OK |
| 28 | Sat Dec 20 | vs Lakers | W103-88 | 7-21 | .250 | NBA TV | Intuit Dome · Inglewood, CA |
| 29 | Tue Dec 23 | vs Rockets | W128-108 | 8-21 | .276 | Peacock | Intuit Dome · Inglewood, CA |
| 30 | Fri Dec 26 | at Blazers | W119-103 | 9-21 | .300 | Amazon | Moda Center · Portland, OR |
| 31 | Sun Dec 28 | vs Pistons | W112-99 | 10-21 | .323 | | Intuit Dome · Inglewood, CA |
| 32 | Tue Dec 30 | vs Kings | W131-90 | 11-21 | .344 | | Intuit Dome · Inglewood, CA |
| 33 | Thu Jan 1 | vs Jazz | W118-101 | 12-21 | .364 | | Intuit Dome · Inglewood, CA |
| 34 | Sat Jan 3 | vs Celtics | L115-146 | 12-22 | .353 | NBA TV | Intuit Dome · Inglewood, CA |
| 35 | Mon Jan 5 | vs Warriors | W103-102 | 13-22 | .371 | Peacock | Intuit Dome · Inglewood, CA |
| 36 | Wed Jan 7 | at Knicks | L111-123 | 13-23 | .361 | | Madison Square Garden · Manhattan, NY |
| 37 | Fri Jan 9 | at Nets | W121-105 | 14-23 | .378 | | Barclays Center · Brooklyn, NY |
| 38 | Sat Jan 10 | at Pistons | W98-92 | 15-23 | .395 | | Little Caesars Arena · Detroit, MI |
| 39 | Mon Jan 12 | vs Hornets | W117-109 | 16-23 | .410 | | Intuit Dome · Inglewood, CA |
| 40 | Wed Jan 14 | vs Wizards | W119-105 | 17-23 | .425 | | Intuit Dome · Inglewood, CA |
| 41 | Fri Jan 16 | at Raptors | W121-117 (OT) | 18-23 | .439 | | Scotiabank Arena · Toronto, ON |
| 42 | Mon Jan 19 | at Wizards | W110-106 | 19-23 | .452 | | Capital One Arena · Washington, D.C. |
| 43 | Tue Jan 20 | at Bulls | L110-138 | 19-24 | .442 | | United Center · Chicago, IL |
| 44 | Thu Jan 22 | vs Lakers | W112-104 | 20-24 | .455 | Amazon | Intuit Dome · Inglewood, CA |
| 45 | Sun Jan 25 | vs Nets | W126-89 | 21-24 | .467 | | Intuit Dome · Inglewood, CA |
| 46 | Tue Jan 27 | at Jazz | W115-103 | 22-24 | .478 | Peacock | Vivint Arena · Salt Lake City, UT |
| 47 | Fri Jan 30 | at Nuggets | L109-122 | 22-25 | .468 | | Ball Arena · Denver, CO |
| 48 | Sun Feb 1 | at Suns | W117-93 | 23-25 | .479 | | Mortgage Matchup Center · Phoenix, AZ |
| 49 | Mon Feb 2 | vs 76ers | L113-128 | 23-26 | .469 | Peacock | Intuit Dome · Inglewood, CA |
| 50 | Wed Feb 4 | vs Cavaliers | L91-124 | 23-27 | .460 | | Intuit Dome · Inglewood, CA |
| 51 | Fri Feb 6 | at Kings | W114-111 | 24-27 | .471 | Amazon | Golden 1 Center · Sacramento, CA |
| 52 | Sun Feb 8 | at T-wolves | W115-96 | 25-27 | .481 | ESPN | Target Center · Minneapolis, MN |
| 53 | Tue Feb 10 | at Rockets | L95-102 | 25-28 | .472 | NBA TV | Toyota Center · Houston, TX |
| 54 | Wed Feb 11 | at Rockets | W105-102 | 26-28 | .481 | | Toyota Center · Houston, TX |
| --all-star break-- |
| 55 | Thu Feb 19 | vs Nuggets | W115-114 | 27-28 | .491 | | Intuit Dome · Inglewood, CA |
| 56 | Fri Feb 20 | at Lakers | L122-125 | 27-29 | .482 | ESPN | Crypto.com Arena · Los Angeles, CA |
| 57 | Sun Feb 22 | vs Magic | L109-111 | 27-30 | .474 | NBA TV | Intuit Dome · Inglewood, CA |
| 58 | Thu Feb 26 | vs T-wolves | L88-94 | 27-31 | .466 | Amazon | Intuit Dome · Inglewood, CA |