| 9 | Sat Dec 6 | at Colorado St | 5:00 PM | 6-2 | .750 | - | CBSSN | Moby Arena · Fort Collins, CO |
| 10 | Sat Dec 13 | vsUTSA | 4:00 PM | 4-4 | .500 | - | ESPN+ | CU Events Center · Boulder, CO |
| 11 | Wed Dec 17 | vsPortland St | 9:00 PM | 5-2 | .714 | - | ESPN+ | CU Events Center · Boulder, CO |
| 12 | Sat Dec 20 | vsStanford | 8:00 PM | 7-1 | .875 | - | ESPNU | CU Events Center · Boulder, CO |
| 13 | Sun Dec 28 | vsN Colorado | 3:00 PM | 8-1 | .889 | - | ESPN+ | CU Events Center · Boulder, CO |
| 14 | Sat Jan 3 | atArizona St | 5:00 PM | 6-2 | .750 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 15 | Wed Jan 7 | vsUtah | 9:00 PM | 6-3 | .667 | - | ESPN+ | CU Events Center · Boulder, CO |
| 16 | Sat Jan 10 | vs#19Texas Tech | 7:00 PM | 6-2 | .750 | - | CBSSN | CU Events Center · Boulder, CO |
| 17 | Wed Jan 14 | atCincinnati | 7:00 PM | 6-2 | .750 | - | Peacock | Fifth Third Arena · Cincinnati, OH |
| 18 | Sat Jan 17 | atWest Virginia | 6:00 PM | 7-2 | .778 | - | CBSSN | WVU Coliseum · Morgantown, WV |
| 19 | Tue Jan 20 | vs#21Kansas | 11:00 PM | 6-3 | .667 | - | ESPN | CU Events Center · Boulder, CO |
| 20 | Sat Jan 24 | vsUCF | 3:00 PM | 7-1 | .875 | - | ESPN+ | CU Events Center · Boulder, CO |
| 21 | Thu Jan 29 | at#10Iowa State | 7:00 PM | 8-0 | 1.000 | - | FS1 | James H. Hilton Coliseum · Ames, IA |
| 22 | Sun Feb 1 | vsTCU | 2:00 PM | 5-2 | .714 | - | TNT | CU Events Center · Boulder, CO |
| 23 | Wed Feb 4 | atBaylor | 8:00 PM | 6-1 | .857 | - | Peacock | Ferrell Center · Waco, TX |
| 24 | Sat Feb 7 | vsArizona St | 9:30 PM | 6-2 | .750 | - | ESPN2 | CU Events Center · Boulder, CO |
| 25 | Wed Feb 11 | at#19Texas Tech | 8:00 PM | 6-2 | .750 | - | ESPN+ | United Supermarkets Arena · Lubbock, TX |
| 26 | Sat Feb 14 | at#9BYU | 4:00 PM | 7-1 | .875 | - | FS1 | Marriott Center · Provo, UT |
| 27 | Sat Feb 21 | vsOklahoma St | 3:30 PM | 8-0 | 1.000 | - | TNT | CU Events Center · Boulder, CO |
| 28 | Wed Feb 25 | vsKansas St | 9:00 PM | 5-3 | .625 | - | FS1 | CU Events Center · Boulder, CO |
| 29 | Sat Feb 28 | at#8Houston | 12:00 PM | 7-1 | .875 | - | | Fertitta Center · Houston, TX |
| 30 | Tue Mar 3 | atUtah | 9:00 PM | 6-3 | .667 | - | ESPN+ | Jon M. Huntsman Center · Salt Lake City, UT |
| 31 | Sat Mar 7 | vs#2Arizona | 11:00 PM | 7-0 | 1.000 | - | ESPN2 | CU Events Center · Boulder, CO |
