| 1 | Mon Nov 3 | vs SE Louisiana | 8:00 PM | 18-14 | .563 | - | | SJB Pavilion · Oxford, MS |
| 2 | Fri Nov 7 | vsUL Monroe | 7:30 PM | 7-25 | .219 | - | | SJB Pavilion · Oxford, MS |
| 3 | Tue Nov 11 | vsMemphis | 9:00 PM | 29-6 | .829 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 4 | Fri Nov 14 | vsBakersfield | 7:30 PM | 14-19 | .424 | - | | SJB Pavilion · Oxford, MS |
| 5 | Tue Nov 18 | vsAustin Peay | 8:00 PM | 14-19 | .424 | - | | SJB Pavilion · Oxford, MS |
| 6 | Tue Nov 25 | atIowa | 9:30 PM | 17-16 | .515 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 7 | Tue Dec 2 | vsMiami | 9:00 PM | 7-24 | .226 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 8 | Sat Dec 6 | at#5St John's | TBD | 31-5 | .861 | - | | Carnesecca Arena · Queens, NY |
| 9 | Sat Dec 13 | vsSouthern Miss | 3:00 PM | 11-22 | .333 | - | | SJB Pavilion · Oxford, MS |
| 10 | Wed Dec 17 | vsAlabama A&M | 8:00 PM | 10-22 | .313 | - | | SJB Pavilion · Oxford, MS |
| 11 | Sun Dec 21 | atNC State | 1:00 PM | 12-19 | .387 | - | ESPN | PNC Arena · Raleigh, NC |
| 12 | Mon Dec 29 | vsAlcorn St | 8:00 PM | 11-21 | .344 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 13 | Sat Jan 3 | atOklahoma | 3:30 PM | 20-14 | .588 | - | SEC Network | Lloyd Noble Center · Norman, OK |
| 14 | Wed Jan 7 | vs#14Arkansas | 9:00 PM | 22-14 | .611 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 15 | Sat Jan 10 | vsMissouri | 6:00 PM | 22-12 | .647 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 16 | Tue Jan 13 | atGeorgia | TBD | 20-13 | .606 | - | | Stegeman Coliseum · Athens, GA |
| 17 | Sat Jan 17 | atMississippi St | 8:30 PM | 21-13 | .618 | - | SEC Network | Humphrey Coliseum · Starkville, MS |
| 18 | Tue Jan 20 | vs#20Auburn | TBD | 32-6 | .842 | - | | SJB Pavilion · Oxford, MS |
| 19 | Sat Jan 24 | at#9Kentucky | 12:00 PM | 24-12 | .667 | - | ESPN | Rupp Arena · Lexington, KY |
| 20 | Sat Jan 31 | vsVanderbilt | 8:30 PM | 20-13 | .606 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 21 | Tue Feb 3 | at#18Tennessee | 7:00 PM | 30-8 | .789 | - | ESPN2 | Thompson-Boling Arena · Knoxville, TN |
| 22 | Sat Feb 7 | atTexas | TBD | 19-16 | .543 | - | | Moody Center · Austin, TX |
| 23 | Wed Feb 11 | vs#15Alabama | 7:00 PM | 28-9 | .757 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 24 | Sat Feb 14 | vsMississippi St | TBD | 21-13 | .618 | - | | SJB Pavilion · Oxford, MS |
| 25 | Wed Feb 18 | atTexas A&M | 7:00 PM | 23-11 | .676 | - | SEC Network | Reed Arena · College Station, TX |
| 26 | Sat Feb 21 | vs#3Florida | TBD | 36-4 | .900 | - | | SJB Pavilion · Oxford, MS |
| 27 | Wed Feb 25 | vsLSU | 9:00 PM | 14-18 | .438 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 28 | Sat Feb 28 | at#20Auburn | 8:30 PM | 32-6 | .842 | - | SEC Network | Neville Arena · Auburn, AL |
| 29 | Wed Mar 4 | atVanderbilt | 6:30 PM | 20-13 | .606 | - | ESPNEWS | Memorial Gymnasium (TN) · Nashville, TN |
| 30 | Sat Mar 7 | vsSouth Carolina | 1:00 PM | 12-20 | .375 | - | SEC Network | SJB Pavilion · Oxford, MS |
