| 1 | Mon Nov 3 | vs SE Missouri St | 8:00 PM | 21-12 | .636 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 2 | Thu Nov 6 | vsChicago St | TBD | 4-28 | .125 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 3 | Mon Nov 10 | vsLindenwood | TBD | 16-17 | .485 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 4 | Sat Nov 15 | vsGrand Canyon | TBD | 26-8 | .765 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 5 | Fri Nov 21 | vsPurdue FW | TBD | 19-13 | .594 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 6 | Thu Nov 27 | vsSanta Clara | 7:00 PM | 21-13 | .618 | - | | Chaifetz Arena · St. Louis, MO |
| 7 | Tue Dec 2 | atLMU | TBD | 17-15 | .531 | - | | Gersten Pavilion · Los Angeles, CA |
| 8 | Sun Dec 7 | vsC Michigan | TBD | 14-17 | .452 | - | | Chaifetz Arena · St. Louis, MO |
| 9 | Sat Dec 13 | vsSan Francisco | TBD | 25-10 | .714 | - | | Chaifetz Arena · St. Louis, MO |
| 10 | Wed Dec 17 | vsBethune | TBD | 17-16 | .515 | - | | Chaifetz Arena · St. Louis, MO |
| 11 | Sun Dec 21 | vsNew Hampshire | TBD | 8-24 | .250 | - | | Chaifetz Arena · St. Louis, MO |
| 12 | Sun Dec 28 | vsTBD | TBD | 0-0 | .000 | - | | Chaifetz Arena · St. Louis, MO |
| 13 | Wed Dec 31 | vsSaint Joseph's | TBD | 22-13 | .629 | - | | Chaifetz Arena · St. Louis, MO |
| 14 | Wed Jan 7 | atVCU | TBD | 28-7 | .800 | - | | Stuart C. Siegel Center · Richmond, VA |
| 15 | Sat Jan 10 | atLa Salle | 4:00 PM | 14-19 | .424 | - | | Tom Gola Arena · Philadelphia, PA |
| 16 | Wed Jan 14 | vsFordham | 8:00 PM | 12-21 | .364 | - | | Chaifetz Arena · St. Louis, MO |
| 17 | Sat Jan 17 | vsRichmond | TBD | 10-22 | .313 | - | | Chaifetz Arena · St. Louis, MO |
| 18 | Tue Jan 20 | atDuquesne | TBD | 13-19 | .406 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 19 | Fri Jan 23 | atSt Bonaventure | TBD | 22-12 | .647 | - | | Reilly Center · Saint Bonaventure, NY |
| 20 | Tue Jan 27 | vsG Washington | 8:00 PM | 21-13 | .618 | - | | Chaifetz Arena · St. Louis, MO |
| 21 | Fri Jan 30 | vsDayton | TBD | 23-11 | .676 | - | | Chaifetz Arena · St. Louis, MO |
| 22 | Tue Feb 3 | atDavidson | TBD | 17-16 | .515 | - | | John M. Belk Arena · Davidson, NC |
| 23 | Sat Feb 7 | vsLa Salle | TBD | 14-19 | .424 | - | | Chaifetz Arena · St. Louis, MO |
| 24 | Fri Feb 13 | atLoyola Chicago | TBD | 25-12 | .676 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 25 | Tue Feb 17 | atRhode Island | TBD | 18-13 | .581 | - | | Ryan Center · Kingston, RI |
| 26 | Fri Feb 20 | vsVCU | TBD | 28-7 | .800 | - | | Chaifetz Arena · St. Louis, MO |
| 27 | Tue Feb 24 | atDayton | TBD | 23-11 | .676 | - | | UD Arena · Dayton, OH |
| 28 | Sat Feb 28 | vsDuquesne | TBD | 13-19 | .406 | - | | Chaifetz Arena · St. Louis, MO |
| 29 | Wed Mar 4 | vsLoyola Chicago | TBD | 25-12 | .676 | - | | Chaifetz Arena · St. Louis, MO |
| 30 | Sat Mar 7 | atGeorge Mason | 4:00 PM | 27-9 | .750 | - | | EagleBank Arena · Fairfax, VA |
