| 1 | Sun Sep 10 | at Bears | W38-20 | 1-0 | 1.000 | Soldier Field · Chicago, IL |
| 2 | Sun Sep 17 | at Falcons | L24-25 | 1-1 | .500 | Mercedes-Benz Stadium · Atlanta, GA |
| 3 | Sun Sep 24 | vs Saints | W18-17 | 2-1 | .667 | Lambeau Field · Green Bay, WI |
| 4 | Thu Sep 28 | vs Lions | L20-34 | 2-2 | .500 | Lambeau Field · Green Bay, WI |
| 5 | Mon Oct 9 | at Raiders | L13-17 | 2-3 | .400 | Allegiant Stadium · Las Vegas, NV |
| 6 | -- BYE WEEK -- |
| 7 | Sun Oct 22 | at Broncos | L17-19 | 2-4 | .333 | Empower Field at Mile High · Denver, CO |
| 8 | Sun Oct 29 | vs Vikings | L10-24 | 2-5 | .286 | Lambeau Field · Green Bay, WI |
| 9 | Sun Nov 5 | vs Rams | W20-3 | 3-5 | .375 | Lambeau Field · Green Bay, WI |
| 10 | Sun Nov 12 | at Steelers | L19-23 | 3-6 | .333 | Acrisure Stadium · Pittsburgh, PA |
| 11 | Sun Nov 19 | vs Chargers | W23-20 | 4-6 | .400 | Lambeau Field · Green Bay, WI |
| 12 | Thu Nov 23 | atLions | W29-22 | 5-6 | .455 | Ford Field · Detroit, MI |
| 13 | Sun Dec 3 | vs Chiefs | W27-19 | 6-6 | .500 | Lambeau Field · Green Bay, WI |
| 14 | Mon Dec 11 | at Giants | L22-24 | 6-7 | .462 | MetLife Stadium · East Rutherford, NJ |
| 15 | Sun Dec 17 | vs Buccaneers | L20-34 | 6-8 | .429 | Lambeau Field · Green Bay, WI |
| 16 | Sun Dec 24 | at Panthers | W33-30 | 7-8 | .467 | Bank of America Stadium · Charlotte, NC |
| 17 | Sun Dec 31 | atVikings | W33-10 | 8-8 | .500 | U.S. Bank Stadium · Minneapolis, MN |
| 18 | Sun Jan 7 | vsBears | W17-9 | 9-8 | .529 | Lambeau Field · Green Bay, WI |
| WC | Sun Jan 14 | at Cowboys | W48-32 | 9-8 | .529 | AT&T Stadium · Arlington, TX |
| DIV | Sat Jan 20 | at 49ers | L21-24 | 9-8 | .529 | Levi's® Stadium · Santa Clara, CA |
