| 1 | Sun Sep 13 | at Bills | L17-27 | 0-0 | .000 | Highmark Stadium · Orchard Park, NY |
| 2 | Sun Sep 20 | vs 49ers | L13-31 | 0-2 | .000 | MetLife Stadium · East Rutherford, NJ |
| 3 | Sun Sep 27 | at Colts | L7-36 | 0-3 | .000 | Lucas Oil Stadium · Indianapolis, IN |
| 4 | Thu Oct 1 | vs Broncos | L28-37 | 0-4 | .000 | MetLife Stadium · East Rutherford, NJ |
| 5 | Sun Oct 11 | vs Cardinals | L10-30 | 0-5 | .000 | MetLife Stadium · East Rutherford, NJ |
| 6 | Sun Oct 18 | at Dolphins | L0-24 | 0-6 | .000 | Hard Rock Stadium · Miami Gardens, FL |
| 7 | Sun Oct 25 | vsBills | L10-18 | 0-7 | .000 | MetLife Stadium · East Rutherford, NJ |
| 8 | Sun Nov 1 | at Chiefs | L9-35 | 0-8 | .000 | Arrowhead Stadium · Kansas City, MO |
| 9 | Mon Nov 9 | vs Patriots | L27-30 | 0-9 | .000 | MetLife Stadium · East Rutherford, NJ |
| 10 | -- BYE WEEK -- |
| 11 | Sun Nov 22 | at Chargers | L28-34 | 0-10 | .000 | SoFi Stadium · Inglewood, CA |
| 12 | Sun Nov 29 | vsDolphins | L3-20 | 0-11 | .000 | MetLife Stadium · East Rutherford, NJ |
| 13 | Sun Dec 6 | vs Raiders | L28-31 | 0-12 | .000 | MetLife Stadium · East Rutherford, NJ |
| 14 | Sun Dec 13 | at Seahawks | L3-40 | 0-13 | .000 | Lumen Field · Seattle, WA |
| 15 | Sun Dec 20 | at Rams | W23-20 | 1-13 | .071 | SoFi Stadium · Inglewood, CA |
| 16 | Sun Dec 27 | vs Browns | W23-16 | 2-13 | .133 | MetLife Stadium · East Rutherford, NJ |
| 17 | Sun Jan 3 | atPatriots | L14-28 | 2-14 | .125 | Gillette Stadium · Foxborough, MA |
