| 1 | Sun Sep 11 | vs Ravens | L9-24 | 0-1 | .000 | MetLife Stadium · East Rutherford, NJ |
| 2 | Sun Sep 18 | at Browns | W31-30 | 1-1 | .500 | FirstEnergy Stadium · Cleveland, OH |
| 3 | Sun Sep 25 | vs Bengals | L12-27 | 1-2 | .333 | MetLife Stadium · East Rutherford, NJ |
| 4 | Sun Oct 2 | at Steelers | W24-20 | 2-2 | .500 | Acrisure Stadium · Pittsburgh, PA |
| 5 | Sun Oct 9 | vs Dolphins | W40-17 | 3-2 | .600 | MetLife Stadium · East Rutherford, NJ |
| 6 | Sun Oct 16 | at Packers | W27-10 | 4-2 | .667 | Lambeau Field · Green Bay, WI |
| 7 | Sun Oct 23 | at Broncos | W16-9 | 5-2 | .714 | Empower Field at Mile High · Denver, CO |
| 8 | Sun Oct 30 | vs Patriots | L17-22 | 5-3 | .625 | MetLife Stadium · East Rutherford, NJ |
| 9 | Sun Nov 6 | vs Bills | W20-17 | 6-3 | .667 | MetLife Stadium · East Rutherford, NJ |
| 10 | -- BYE WEEK -- |
| 11 | Sun Nov 20 | atPatriots | L3-10 | 6-4 | .600 | Gillette Stadium · Foxborough, MA |
| 12 | Sun Nov 27 | vs Bears | W31-10 | 7-4 | .636 | MetLife Stadium · East Rutherford, NJ |
| 13 | Sun Dec 4 | at Vikings | L22-27 | 7-5 | .583 | U.S. Bank Stadium · Minneapolis, MN |
| 14 | Sun Dec 11 | atBills | L12-20 | 7-6 | .538 | Highmark Stadium · Orchard Park, NY |
| 15 | Sun Dec 18 | vs Lions | L17-20 | 7-7 | .500 | MetLife Stadium · East Rutherford, NJ |
| 16 | Thu Dec 22 | vs Jaguars | L3-19 | 7-8 | .467 | MetLife Stadium · East Rutherford, NJ |
| 17 | Sun Jan 1 | at Seahawks | L6-23 | 7-9 | .438 | Lumen Field · Seattle, WA |
| 18 | Sun Jan 8 | atDolphins | L6-11 | 7-10 | .412 | Hard Rock Stadium · Miami Gardens, FL |
