| 3 | Sat Oct 24 | vs Bucks | 7:30 PM | 0-2 | .000 | NBA TV | Xfinity Mobile Arena · Philadelphia, PA |
| 4 | Sun Oct 25 | vsPistons | 7:30 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 5 | Wed Oct 28 | atPacers | 7:00 PM | 1-0 | 1.000 | ESPN | Gainbridge Fieldhouse · Indianapolis, IN |
| 6 | Fri Oct 30 | vsKnicks | 7:30 PM | 0-1 | .000 | Prime Video | Xfinity Mobile Arena · Philadelphia, PA |
| 7 | Sat Oct 31 | atHornets | 6:00 PM | 1-0 | 1.000 | NBA TV | Spectrum Center · Charlotte, NC |
| 8 | Mon Nov 2 | vsBulls | 7:30 PM | 1-1 | .500 | | Xfinity Mobile Arena · Philadelphia, PA |
| 9 | Wed Nov 4 | atPistons | 7:00 PM | 1-0 | 1.000 | ESPN | Little Caesars Arena · Detroit, MI |
| 10 | Fri Nov 6 | atCavaliers | 7:30 PM | 0-1 | .000 | Prime Video | Rocket Mortgage FieldHouse · Cleveland, OH |
| 11 | Sun Nov 8 | atBulls | 3:30 PM | 1-1 | .500 | | United Center · Chicago, IL |
| 12 | Tue Nov 10 | vsCeltics | 8:00 PM | 0-1 | .000 | NBC | Xfinity Mobile Arena · Philadelphia, PA |
| 13 | Thu Nov 12 | vsRaptors | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 14 | Sun Nov 15 | vsPacers | 1:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 15 | Mon Nov 16 | atNets | 7:30 PM | 0-1 | .000 | | Barclays Center · Brooklyn, NY |
| 16 | Wed Nov 18 | atMagic | 7:00 PM | 0-1 | .000 | | Kia Center · Orlando, FL |
| 17 | Sat Nov 21 | vsBucks | 1:00 PM | 0-2 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 18 | Mon Nov 23 | vsBlazers | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 19 | Wed Nov 25 | vsHeat | 5:00 PM | 0-1 | .000 | ESPN | Xfinity Mobile Arena · Philadelphia, PA |
| 20 | Fri Nov 27 | atPacers | 7:30 PM | 1-0 | 1.000 | | Gainbridge Fieldhouse · Indianapolis, IN |
| 21 | Sat Nov 28 | atRockets | 8:30 PM | 1-0 | 1.000 | NBA TV | Toyota Center · Houston, TX |
| 22 | Tue Dec 1 | vsGrizzlies | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 23 | Wed Dec 2 | vsNuggets | 7:00 PM | 0-1 | .000 | NBA TV | Xfinity Mobile Arena · Philadelphia, PA |
| 24 | Sat Dec 12 | vsMagic | 7:30 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 25 | Mon Dec 14 | atMagic | 7:00 PM | 0-1 | .000 | NBCSN | Kia Center · Orlando, FL |
| 26 | Thu Dec 17 | vsMavericks | 7:00 PM | 0-1 | .000 | NBA TV | Xfinity Mobile Arena · Philadelphia, PA |
| 27 | Mon Dec 21 | atHornets | 7:00 PM | 1-0 | 1.000 | | Spectrum Center · Charlotte, NC |
| 28 | Wed Dec 23 | vsRockets | 7:30 PM | 1-0 | 1.000 | Prime Video | Xfinity Mobile Arena · Philadelphia, PA |
| 29 | Fri Dec 25 | atLakers | 5:00 PM | 1-0 | 1.000 | ABC | Crypto.com Arena · Los Angeles, CA |
| 30 | Sun Dec 27 | atClippers | 9:00 PM | 1-0 | 1.000 | | Intuit Dome · Inglewood, CA |
| 31 | Tue Dec 29 | atKings | 10:00 PM | 0-1 | .000 | | Golden 1 Center · Sacramento, CA |
| 32 | Wed Dec 30 | atSuns | 9:00 PM | 0-1 | .000 | | Mortgage Matchup Center · Phoenix, AZ |
| 33 | Fri Jan 1 | atBucks | 8:00 PM | 0-2 | .000 | | Fiserv Forum · Milwaukee, WI |
| 34 | Mon Jan 4 | vsHawks | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 35 | Wed Jan 6 | vsThunder | 7:30 PM | 2-0 | 1.000 | ESPN | Xfinity Mobile Arena · Philadelphia, PA |
| 36 | Fri Jan 8 | vsHeat | 7:00 PM | 0-1 | .000 | ESPN | Xfinity Mobile Arena · Philadelphia, PA |
| 37 | Sun Jan 10 | atRaptors | 6:00 PM | 1-0 | 1.000 | | Scotiabank Arena · Toronto, ON |
| 38 | Tue Jan 12 | vsWizards | 8:00 PM | 1-0 | 1.000 | NBC | Xfinity Mobile Arena · Philadelphia, PA |
| 39 | Thu Jan 14 | vsNets | 7:00 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 40 | Sat Jan 16 | vsT-wolves | 12:30 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 41 | Mon Jan 18 | atHawks | 2:30 PM | 1-0 | 1.000 | NBC | State Farm Arena · Atlanta, GA |
| 42 | Tue Jan 19 | vsPacers | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 43 | Thu Jan 21 | atCeltics | 7:30 PM | 0-1 | .000 | Prime Video | TD Garden · Boston, MA |
| 44 | Sat Jan 23 | atBulls | 5:00 PM | 1-1 | .500 | NBA TV | United Center · Chicago, IL |
| 45 | Mon Jan 25 | vsClippers | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 46 | Wed Jan 27 | vsKings | 7:00 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 47 | Thu Jan 28 | atPelicans | 8:00 PM | 0-1 | .000 | | Smoothie King Center · New Orleans, LA |
| 48 | Sat Jan 30 | atHeat | 12:30 PM | 0-1 | .000 | ABC | Kaseya Center · Miami, FL |
| 49 | Mon Feb 1 | vsPelicans | 7:00 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 50 | Wed Feb 3 | atGrizzlies | 8:00 PM | 1-0 | 1.000 | | FedExForum · Memphis, TN |
| 51 | Fri Feb 5 | vsPistons | 7:00 PM | 1-0 | 1.000 | Prime Video | Xfinity Mobile Arena · Philadelphia, PA |
| 52 | Sun Feb 7 | vsCeltics | 7:00 PM | 0-1 | .000 | NBC | Xfinity Mobile Arena · Philadelphia, PA |
| 53 | Mon Feb 8 | vsNets | 7:00 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 54 | Thu Feb 11 | vsKnicks | 7:00 PM | 0-1 | .000 | Prime Video | Xfinity Mobile Arena · Philadelphia, PA |
| 55 | Sat Feb 13 | atThunder | 5:30 PM | 2-0 | 1.000 | Prime Video | Paycom Center · Oklahoma City, OK |
| 56 | Mon Feb 15 | atMavericks | 2:30 PM | 0-1 | .000 | NBC | American Airlines Center · Dallas, TX |
| 57 | Wed Feb 17 | vsSuns | 7:00 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 58 | Thu Feb 25 | atNets | 7:30 PM | 0-1 | .000 | | Barclays Center · Brooklyn, NY |
| 59 | Sat Feb 27 | atKnicks | 8:30 PM | 0-1 | .000 | ABC | Madison Square Garden · Manhattan, NY |
| 60 | Mon Mar 1 | atCavaliers | 7:00 PM | 0-1 | .000 | NBCSN | Rocket Mortgage FieldHouse · Cleveland, OH |
| 61 | Wed Mar 3 | vsHornets | 7:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 62 | Thu Mar 4 | vsLakers | 7:00 PM | 1-0 | 1.000 | Prime Video | Xfinity Mobile Arena · Philadelphia, PA |
| 63 | Sun Mar 7 | atCeltics | 1:00 PM | 0-1 | .000 | ABC | TD Garden · Boston, MA |
| 64 | Mon Mar 8 | vsJazz | 7:00 PM | 0-1 | .000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 65 | Thu Mar 11 | atSpurs | 7:30 PM | 0-1 | .000 | Prime Video | Frost Bank Center · San Antonio, TX |
| 66 | Sat Mar 13 | atT-wolves | 8:30 PM | 1-0 | 1.000 | ABC | Target Center · Minneapolis, MN |
| 67 | Mon Mar 15 | vsRaptors | 7:00 PM | 1-0 | 1.000 | NBCSN | Xfinity Mobile Arena · Philadelphia, PA |
| 68 | Wed Mar 17 | vsBulls | 7:00 PM | 1-1 | .500 | | Xfinity Mobile Arena · Philadelphia, PA |
| 69 | Thu Mar 18 | atWizards | 7:00 PM | 1-0 | 1.000 | NBA TV | Capital One Arena · Washington, D.C. |
| 70 | Sun Mar 21 | vsSpurs | 7:30 PM | 0-1 | .000 | NBC | Xfinity Mobile Arena · Philadelphia, PA |
| 71 | Tue Mar 23 | atJazz | 9:00 PM | 0-1 | .000 | | Vivint Arena · Salt Lake City, UT |
| 72 | Wed Mar 24 | atWarriors | 10:00 PM | 0-1 | .000 | ESPN | Chase Center · San Francisco, CA |
| 73 | Fri Mar 26 | atBlazers | 10:00 PM | 1-0 | 1.000 | NBA TV | Moda Center · Portland, OR |
| 74 | Sun Mar 28 | atNuggets | 10:00 PM | 0-1 | .000 | NBC | Ball Arena · Denver, CO |
| 75 | Wed Mar 31 | vsWarriors | 7:00 PM | 0-1 | .000 | ESPN | Xfinity Mobile Arena · Philadelphia, PA |
| 76 | Fri Apr 2 | atWizards | 7:00 PM | 1-0 | 1.000 | | Capital One Arena · Washington, D.C. |
| 77 | Sun Apr 4 | vsHawks | 1:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
| 78 | Tue Apr 6 | atRaptors | 7:30 PM | 1-0 | 1.000 | | Scotiabank Arena · Toronto, ON |
| 79 | Thu Apr 8 | atHeat | 7:00 PM | 0-1 | .000 | Prime Video | Kaseya Center · Miami, FL |
| 80 | Sun Apr 11 | vsHornets | 6:00 PM | 1-0 | 1.000 | | Xfinity Mobile Arena · Philadelphia, PA |
