| 1 | Wed Dec 23 | vs Wizards | W113-107 | 1-0 | 1.000 | Wells Fargo Center · Philadelphia, PA |
| 2 | Sat Dec 26 | at Knicks | W109-89 | 2-0 | 1.000 | Madison Square Garden · Manhattan, NY |
| 3 | Sun Dec 27 | at Cavaliers | L94-118 | 2-1 | .667 | Rocket Mortgage FieldHouse · Cleveland, OH |
| 4 | Tue Dec 29 | vs Raptors | W100-93 | 3-1 | .750 | Wells Fargo Center · Philadelphia, PA |
| 5 | Thu Dec 31 | at Magic | W116-92 | 4-1 | .800 | Amway Center · Orlando, FL |
| 6 | Sat Jan 2 | vs Hornets | W127-112 | 5-1 | .833 | Wells Fargo Center · Philadelphia, PA |
| 7 | Mon Jan 4 | vsHornets | W118-101 | 6-1 | .857 | Wells Fargo Center · Philadelphia, PA |
| 8 | Wed Jan 6 | vsWizards | W141-136 | 7-1 | .875 | Wells Fargo Center · Philadelphia, PA |
| 9 | Thu Jan 7 | at Nets | L109-122 | 7-2 | .778 | Barclays Center · Brooklyn, NY |
| 10 | Sat Jan 9 | vs Nuggets | L103-115 | 7-3 | .700 | Wells Fargo Center · Philadelphia, PA |
| 11 | Mon Jan 11 | at Hawks | L94-112 | 7-4 | .636 | State Farm Arena · Atlanta, GA |
| 12 | Tue Jan 12 | vs Heat | W137-134 (OT) | 8-4 | .667 | Wells Fargo Center · Philadelphia, PA |
| 13 | Thu Jan 14 | vsHeat | W125-108 | 9-4 | .692 | Wells Fargo Center · Philadelphia, PA |
| 14 | Sat Jan 16 | at Grizzlies | L104-106 | 9-5 | .643 | FedExForum · Memphis, TN |
| 15 | Wed Jan 20 | vs Celtics | W117-109 | 10-5 | .667 | Wells Fargo Center · Philadelphia, PA |
| 16 | Fri Jan 22 | vsCeltics | W122-110 | 11-5 | .688 | Wells Fargo Center · Philadelphia, PA |
| 17 | Sat Jan 23 | at Pistons | W114-110 | 12-5 | .706 | Little Caesars Arena · Detroit, MI |
| 18 | Mon Jan 25 | atPistons | L104-119 | 12-6 | .667 | Little Caesars Arena · Detroit, MI |
| 19 | Wed Jan 27 | vs Lakers | W107-106 | 13-6 | .684 | Wells Fargo Center · Philadelphia, PA |
| 20 | Fri Jan 29 | at T-wolves | W118-94 | 14-6 | .700 | Target Center · Minneapolis, MN |
| 21 | Sun Jan 31 | at Pacers | W119-110 | 15-6 | .714 | Gainbridge Fieldhouse · Indianapolis, IN |
| 22 | Wed Feb 3 | atHornets | W118-111 | 16-6 | .727 | Spectrum Center · Charlotte, NC |
| 23 | Thu Feb 4 | vs Blazers | L105-121 | 16-7 | .696 | Wells Fargo Center · Philadelphia, PA |
| 24 | Sat Feb 6 | vsNets | W124-108 | 17-7 | .708 | Wells Fargo Center · Philadelphia, PA |
| 25 | Tue Feb 9 | at Kings | W119-111 | 18-7 | .720 | Golden 1 Center · Sacramento, CA |
| 26 | Thu Feb 11 | atBlazers | L114-118 | 18-8 | .692 | Moda Center · Portland, OR |
| 27 | Sat Feb 13 | at Suns | L111-120 | 18-9 | .667 | Footprint Center · Phoenix, AZ |
| 28 | Mon Feb 15 | at Jazz | L123-134 | 18-10 | .643 | Vivint Arena · Salt Lake City, UT |
| 29 | Wed Feb 17 | vs Rockets | W118-113 | 19-10 | .655 | Wells Fargo Center · Philadelphia, PA |
| 30 | Fri Feb 19 | vs Bulls | W112-105 | 20-10 | .667 | Wells Fargo Center · Philadelphia, PA |
| 31 | Sun Feb 21 | atRaptors | L103-110 | 20-11 | .645 | Scotiabank Arena · Toronto, ON |
| 32 | Tue Feb 23 | atRaptors | W109-102 | 21-11 | .656 | Scotiabank Arena · Toronto, ON |
| 33 | Thu Feb 25 | vs Mavericks | W111-97 | 22-11 | .667 | Wells Fargo Center · Philadelphia, PA |
| 34 | Sat Feb 27 | vsCavaliers | L109-112 (OT) | 22-12 | .647 | Wells Fargo Center · Philadelphia, PA |
| 35 | Mon Mar 1 | vsPacers | W130-114 | 23-12 | .657 | Wells Fargo Center · Philadelphia, PA |
| 36 | Wed Mar 3 | vsJazz | W131-123 (OT) | 24-12 | .667 | Wells Fargo Center · Philadelphia, PA |
| 37 | Thu Mar 11 | atBulls | W127-105 | 25-12 | .676 | United Center · Chicago, IL |
| 38 | Fri Mar 12 | atWizards | W127-101 | 26-12 | .684 | Capital One Arena · Washington, D.C. |
| 39 | Sun Mar 14 | vs Spurs | W134-99 | 27-12 | .692 | Wells Fargo Center · Philadelphia, PA |
| 40 | Tue Mar 16 | vsKnicks | W99-96 | 28-12 | .700 | Wells Fargo Center · Philadelphia, PA |
| 41 | Wed Mar 17 | vs Bucks | L105-109 (OT) | 28-13 | .683 | Wells Fargo Center · Philadelphia, PA |
| 42 | Sat Mar 20 | vsKings | W129-105 | 29-13 | .690 | Wells Fargo Center · Philadelphia, PA |
| 43 | Sun Mar 21 | atKnicks | W101-100 (OT) | 30-13 | .698 | Madison Square Garden · Manhattan, NY |
| 44 | Tue Mar 23 | at Warriors | W108-98 | 31-13 | .705 | Chase Center · San Francisco, CA |
| 45 | Thu Mar 25 | atLakers | W109-101 | 32-13 | .711 | Crypto.com Arena · Los Angeles, CA |
| 46 | Sat Mar 27 | at Clippers | L112-122 | 32-14 | .696 | Crypto.com Arena · Los Angeles, CA |
| 47 | Tue Mar 30 | atNuggets | L95-104 | 32-15 | .681 | Ball Arena · Denver, CO |
| 48 | Thu Apr 1 | atCavaliers | W114-94 | 33-15 | .688 | Rocket Mortgage FieldHouse · Cleveland, OH |
| 49 | Sat Apr 3 | vsT-wolves | W122-113 | 34-15 | .694 | Wells Fargo Center · Philadelphia, PA |
| 50 | Sun Apr 4 | vsGrizzlies | L100-116 | 34-16 | .680 | Wells Fargo Center · Philadelphia, PA |
| 51 | Tue Apr 6 | atCeltics | W106-96 | 35-16 | .686 | TD Garden · Boston, MA |
| 52 | Fri Apr 9 | at Pelicans | L94-101 | 35-17 | .673 | Smoothie King Center · New Orleans, LA |
| 53 | Sat Apr 10 | at Thunder | W117-93 | 36-17 | .679 | Paycom Center · Oklahoma City, OK |
| 54 | Mon Apr 12 | atMavericks | W113-95 | 37-17 | .685 | American Airlines Center · Dallas, TX |
| 55 | Wed Apr 14 | vsNets | W123-117 | 38-17 | .691 | Wells Fargo Center · Philadelphia, PA |
| 56 | Fri Apr 16 | vsClippers | W106-103 | 39-17 | .696 | Wells Fargo Center · Philadelphia, PA |
| 57 | Mon Apr 19 | vsWarriors | L96-107 | 39-18 | .684 | Wells Fargo Center · Philadelphia, PA |
| 58 | Wed Apr 21 | vsSuns | L113-116 | 39-19 | .672 | Wells Fargo Center · Philadelphia, PA |
| 59 | Thu Apr 22 | atBucks | L117-124 | 39-20 | .661 | Fiserv Forum · Milwaukee, WI |
| 60 | Sat Apr 24 | atBucks | L94-132 | 39-21 | .650 | Fiserv Forum · Milwaukee, WI |
| 61 | Mon Apr 26 | vsThunder | W121-90 | 40-21 | .656 | Wells Fargo Center · Philadelphia, PA |
| 62 | Wed Apr 28 | vsHawks | W127-83 | 41-21 | .661 | Wells Fargo Center · Philadelphia, PA |
| 63 | Fri Apr 30 | vsHawks | W126-104 | 42-21 | .667 | Wells Fargo Center · Philadelphia, PA |
| 64 | Sun May 2 | atSpurs | W113-111 (OT) | 43-21 | .672 | AT&T Center · San Antonio, TX |
| 65 | Mon May 3 | atBulls | W106-94 | 44-21 | .677 | United Center · Chicago, IL |
| 66 | Wed May 5 | atRockets | W135-115 | 45-21 | .682 | Toyota Center · Houston, TX |
| 67 | Fri May 7 | vsPelicans | W109-107 | 46-21 | .687 | Wells Fargo Center · Philadelphia, PA |
| 68 | Sat May 8 | vsPistons | W118-104 | 47-21 | .691 | Wells Fargo Center · Philadelphia, PA |
| 69 | Tue May 11 | atPacers | L94-103 | 47-22 | .681 | Gainbridge Fieldhouse · Indianapolis, IN |
| 70 | Thu May 13 | atHeat | L94-106 | 47-23 | .671 | FTX Arena · Miami, FL |
| 71 | Fri May 14 | vsMagic | W122-97 | 48-23 | .676 | Wells Fargo Center · Philadelphia, PA |
| 72 | Sun May 16 | vsMagic | W128-117 | 49-23 | .681 | Wells Fargo Center · Philadelphia, PA |
| 1 | Sun May 23 | vsWizards | W125-118 | 1-0 | 1.000 | Wells Fargo Center · Philadelphia, PA |
| 2 | Wed May 26 | vsWizards | W120-95 | 2-0 | 1.000 | Wells Fargo Center · Philadelphia, PA |
| 3 | Sat May 29 | atWizards | W132-103 | 3-0 | 1.000 | Capital One Arena · Washington, D.C. |
| 4 | Mon May 31 | atWizards | L114-122 | 3-1 | .750 | Capital One Arena · Washington, D.C. |
| 5 | Wed Jun 2 | vsWizards | W129-112 | 4-1 | .800 | Wells Fargo Center · Philadelphia, PA |
| 1 | Sun Jun 6 | vsHawks | L124-128 | 0-1 | .000 | Wells Fargo Center · Philadelphia, PA |
| 2 | Tue Jun 8 | vsHawks | W118-102 | 1-1 | .500 | Wells Fargo Center · Philadelphia, PA |
| 3 | Fri Jun 11 | atHawks | W127-111 | 2-1 | .667 | State Farm Arena · Atlanta, GA |
| 4 | Mon Jun 14 | atHawks | L100-103 | 2-2 | .500 | State Farm Arena · Atlanta, GA |
| 5 | Wed Jun 16 | vsHawks | L106-109 | 2-3 | .400 | Wells Fargo Center · Philadelphia, PA |
| 6 | Fri Jun 18 | atHawks | W104-99 | 3-3 | .500 | State Farm Arena · Atlanta, GA |
| 7 | Sun Jun 20 | vsHawks | L96-103 | 3-4 | .429 | Wells Fargo Center · Philadelphia, PA |
