| 1 | Tue Nov 4 | vs Georgia So | 7:00 PM | 17-16 | .515 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 2 | Sat Nov 8 | atRichmond | TBD | 10-22 | .313 | - | ESPN+ | Robins Center · Richmond, VA |
| 3 | Thu Nov 13 | vsTBD | 7:00 PM | 0-0 | .000 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 4 | Tue Nov 18 | atUNC Wilmington | TBD | 27-8 | .771 | - | | Trask Coliseum · Wilmington, NC |
| 5 | Fri Nov 21 | vsCharleston So | 7:00 PM | 10-22 | .313 | - | ESPN+ | Williams Arena at Minges Coliseum · Greenville, NC |
| 6 | Tue Nov 25 | vs#22Michigan St | 1:00 PM | 30-7 | .811 | - | FS2 | Williams Arena at Minges Coliseum · Greenville, NC |
| 7 | Thu Nov 27 | vsSt Bonaventure | 12:00 PM | 22-12 | .647 | - | FS1 | Williams Arena at Minges Coliseum · Greenville, NC |
| 8 | Tue Dec 2 | vsMD-Eastern | TBD | 6-25 | .194 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 9 | Sat Dec 6 | vsUNC Greensboro | TBD | 20-12 | .625 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 10 | Thu Dec 11 | vsAppalachian St | TBD | 17-14 | .548 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 11 | Sun Dec 14 | vsBuffalo | 1:00 PM | 9-22 | .290 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 12 | Wed Dec 17 | vsPresbyterian | TBD | 14-19 | .424 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 13 | Mon Dec 22 | at#25UNC | 8:00 PM | 23-14 | .622 | - | ACC Network | Dean E. Smith Center · Chapel Hill, NC |
| 14 | Wed Dec 31 | vsTulane | TBD | 19-15 | .559 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 15 | Wed Jan 7 | atTemple | TBD | 17-15 | .531 | - | | Liacouras Center · Philadelphia, PA |
| 16 | Sun Jan 11 | vsUAB | TBD | 24-13 | .649 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 17 | Wed Jan 14 | atSouth Florida | TBD | 13-19 | .406 | - | | Yuengling Center · Tampa, FL |
| 18 | Sun Jan 18 | vsCharlotte | TBD | 11-22 | .333 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 19 | Wed Jan 21 | atWichita St | TBD | 19-15 | .559 | - | | Charles Koch Arena · Wichita, KS |
| 20 | Sat Jan 24 | atNorth Texas | TBD | 27-9 | .750 | - | | The Super Pit · Denton, TX |
| 21 | Wed Jan 28 | vsRice | TBD | 13-19 | .406 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 22 | Sun Feb 1 | atFAU | TBD | 18-16 | .529 | - | | FAU Arena · Boca Raton, FL |
| 23 | Sat Feb 7 | vsTemple | TBD | 17-15 | .531 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 24 | Wed Feb 11 | vsUTSA | TBD | 12-19 | .387 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 25 | Sat Feb 14 | atRice | TBD | 13-19 | .406 | - | | Tudor Fieldhouse · Houston, TX |
| 26 | Wed Feb 18 | vsWichita St | TBD | 19-15 | .559 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 27 | Sat Feb 21 | atCharlotte | TBD | 11-22 | .333 | - | | Dale F. Halton Arena · Charlotte, NC |
| 28 | Wed Feb 25 | atUTSA | TBD | 12-19 | .387 | - | | UTSA Convocation Center · San Antonio, TX |
| 29 | Sun Mar 1 | vsMemphis | TBD | 29-6 | .829 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 30 | Wed Mar 4 | vsTulsa | TBD | 13-20 | .394 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 31 | Sun Mar 8 | atUAB | TBD | 24-13 | .649 | - | | Bartow Arena · Birmingham, AL |
