| 1 | Wed Nov 10 | vs MD-Eastern | W72-49 | 1-0 | 1.000 | - | | Liacouras Center · Philadelphia, PA |
| 2 | Sat Nov 13 | vs USC | L71-76 | 1-1 | .500 | - | | Liacouras Center · Philadelphia, PA |
| 3 | Thu Nov 18 | vs Clemson | L48-75 | 1-2 | .333 | - | ESPN2 | Liacouras Center · Philadelphia, PA |
| 4 | Fri Nov 19 | vs Boise St | L62-82 | 1-3 | .250 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 5 | Sun Nov 21 | at Elon | W75-58 | 2-3 | .400 | - | ESPNU | Schar Center · Elon, NC |
| 6 | Sat Nov 27 | vs Delaware | W75-74 | 3-3 | .500 | - | | Liacouras Center · Philadelphia, PA |
| 7 | Wed Dec 1 | vs La Salle | W73-57 | 4-3 | .571 | - | | Liacouras Center · Philadelphia, PA |
| 8 | Sat Dec 4 | vs Penn | W81-72 | 5-3 | .625 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 9 | Tue Dec 7 | at Vanderbilt | W72-68 (OT) | 6-3 | .667 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 10 | Sat Dec 11 | at Saint Joseph's | L49-68 | 6-4 | .600 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 11 | Wed Dec 15 | vs UCF | L48-65 | 6-5 | .545 | - | ESPN2 | Liacouras Center · Philadelphia, PA |
| 13 | Wed Dec 22 | vs Delaware St | W85-48 | 7-5 | .583 | - | | Liacouras Center · Philadelphia, PA |
| 15 | Sun Jan 2 | vs #12Houston | L61-66 | 7-6 | .538 | - | ESPN | Liacouras Center · Philadelphia, PA |
| 16 | Wed Jan 5 | atUCF | W66-62 | 8-6 | .571 | - | | Addition Financial Arena · Orlando, FL |
| 17 | Sat Jan 8 | vs E Carolina | W78-75 | 9-6 | .600 | - | | Liacouras Center · Philadelphia, PA |
| 18 | Wed Jan 12 | at Tulsa | W69-64 | 10-6 | .625 | - | ESPNU | Donald W. Reynolds Center · Tulsa, OK |
| 20 | Sat Jan 22 | at South Florida | PPD | 17-12 | .586 | - | | Yuengling Center · Tampa, FL |
| 21 | Tue Jan 25 | vs Cincinnati | W61-58 | 11-6 | .647 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 22 | Sat Jan 29 | at SMU | L61-69 | 11-7 | .611 | - | | Moody Coliseum · Dallas, TX |
| 23 | Wed Feb 2 | atE Carolina | W71-63 | 12-7 | .632 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 24 | Sat Feb 5 | vsTulsa | W67-58 | 13-7 | .650 | - | | Liacouras Center · Philadelphia, PA |
| 25 | Mon Feb 7 | atSouth Florida | L49-52 | 13-8 | .619 | - | | Yuengling Center · Tampa, FL |
| 26 | Sat Feb 12 | at Tulane | L83-92 (OT) | 13-9 | .591 | - | | Devlin Fieldhouse · New Orleans, LA |
| 27 | Wed Feb 16 | vsSMU | W64-57 | 14-9 | .609 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 28 | Sun Feb 20 | atCincinnati | W75-71 | 15-9 | .625 | - | ESPN2 | Fifth Third Arena · Cincinnati, OH |
| 29 | Thu Feb 24 | at Memphis | L64-78 | 15-10 | .600 | - | ESPN2 | FedExForum · Memphis, TN |
| 30 | Sun Feb 27 | vsTulane | W75-70 | 16-10 | .615 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 31 | Thu Mar 3 | at#14Houston | L46-84 | 16-11 | .593 | - | ESPN2 | Fertitta Center · Houston, TX |
| 32 | Sun Mar 6 | vsSouth Florida | W75-47 | 17-11 | .607 | - | | Liacouras Center · Philadelphia, PA |
| 33 | Fri Mar 11 | vsTulane | L60-69 | 17-12 | .586 | - | ESPN2 | Liacouras Center · Philadelphia, PA |
Drexel
#22Villanova
Wichita St