| 1 | Thu Sep 9 | at Buccaneers | L29-31 | 0-1 | .000 | Raymond James Stadium · Tampa, FL |
| 2 | Sun Sep 19 | at Chargers | W20-17 | 1-1 | .500 | SoFi Stadium · Inglewood, CA |
| 3 | Mon Sep 27 | vs Eagles | W41-21 | 2-1 | .667 | AT&T Stadium · Arlington, TX |
| 4 | Sun Oct 3 | vs Panthers | W36-28 | 3-1 | .750 | AT&T Stadium · Arlington, TX |
| 5 | Sun Oct 10 | vs Giants | W44-20 | 4-1 | .800 | AT&T Stadium · Arlington, TX |
| 6 | Sun Oct 17 | at Patriots | W35-29 (OT) | 5-1 | .833 | Gillette Stadium · Foxborough, MA |
| 7 | -- BYE WEEK -- |
| 8 | Sun Oct 31 | at Vikings | W20-16 | 6-1 | .857 | U.S. Bank Stadium · Minneapolis, MN |
| 9 | Sun Nov 7 | vs Broncos | L16-30 | 6-2 | .750 | AT&T Stadium · Arlington, TX |
| 10 | Sun Nov 14 | vs Falcons | W43-3 | 7-2 | .778 | AT&T Stadium · Arlington, TX |
| 11 | Sun Nov 21 | at Chiefs | L9-19 | 7-3 | .700 | Arrowhead Stadium · Kansas City, MO |
| 12 | Thu Nov 25 | vs Raiders | L33-36 (OT) | 7-4 | .636 | AT&T Stadium · Arlington, TX |
| 13 | Thu Dec 2 | at Saints | W27-17 | 8-4 | .667 | Caesars Superdome · New Orleans, LA |
| 14 | Sun Dec 12 | at Commanders | W27-20 | 9-4 | .692 | FedEx Field · North Englewood, MD |
| 15 | Sun Dec 19 | atGiants | W21-6 | 10-4 | .714 | MetLife Stadium · East Rutherford, NJ |
| 16 | Sun Dec 26 | vsCommanders | W56-14 | 11-4 | .733 | AT&T Stadium · Arlington, TX |
| 17 | Sun Jan 2 | vs Cardinals | L22-25 | 11-5 | .688 | AT&T Stadium · Arlington, TX |
| WC | Sun Jan 16 | vs 49ers | L17-23 | 12-5 | .706 | AT&T Stadium · Arlington, TX |
