| 1 | Tue Nov 7 | vs Presbyterian | L62-68 | 0-1 | .000 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 2 | Fri Nov 10 | vs SC Upstate | W74-67 | 1-1 | .500 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 3 | Tue Nov 14 | vs UNC Greensboro | W74-70 | 2-1 | .667 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 4 | Fri Nov 17 | vs C Arkansas | W75-71 | 3-1 | .750 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 5 | Thu Nov 23 | vs NC State | L78-84 | 3-2 | .600 | - | ESPN2 | Memorial Gymnasium (TN) · Nashville, TN |
| 6 | Fri Nov 24 | at Arizona St | L67-82 | 3-3 | .500 | - | ESPN2 | Desert Financial Arena · Tempe, AZ |
| 7 | Wed Nov 29 | vs Boston College | L62-80 | 3-4 | .429 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 8 | Sat Dec 2 | vs Alabama A&M | W78-59 | 4-4 | .500 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 9 | Wed Dec 6 | vs San Francisco | L60-73 | 4-5 | .444 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 10 | Sat Dec 16 | at Texas Tech | L54-76 | 4-6 | .400 | - | | United Supermarkets Arena · Lubbock, TX |
| 11 | Tue Dec 19 | vs W Carolina | L62-63 | 4-7 | .364 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 12 | Sat Dec 23 | at #23Memphis | L75-77 | 4-8 | .333 | - | CBS | FedExForum · Memphis, TN |
| 13 | Sat Dec 30 | vs Dartmouth | W69-53 | 5-8 | .385 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 14 | Sat Jan 6 | vs Alabama | L75-78 | 5-9 | .357 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 15 | Tue Jan 9 | at LSU | L69-77 | 5-10 | .333 | - | SEC Network | Pete Maravich Assembly Center · Baton Rouge, LA |
| 16 | Sat Jan 13 | at Ole Miss | L56-69 | 5-11 | .313 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 17 | Wed Jan 17 | vs #13Auburn | L65-80 | 5-12 | .294 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 18 | Sat Jan 20 | at Mississippi St | L55-68 | 5-13 | .278 | - | SEC Network | Humphrey Coliseum · Starkville, MS |
| 19 | Sat Jan 27 | vs #5Tennessee | L62-75 | 5-14 | .263 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 20 | Wed Jan 31 | at#16Auburn | L54-81 | 5-15 | .250 | - | ESPN2 | Neville Arena · Auburn, AL |
| 21 | Sat Feb 3 | vs Missouri | W68-61 | 6-15 | .286 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 22 | Tue Feb 6 | vs #17Kentucky | L77-109 | 6-16 | .273 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 23 | Sat Feb 10 | at #15South Carolina | L60-75 | 6-17 | .261 | - | SEC Network | Colonial Life Arena · Columbia, SC |
| 24 | Tue Feb 13 | vs Texas A&M | W74-73 | 7-17 | .292 | - | ESPNU | Memorial Gymnasium (TN) · Nashville, TN |
| 25 | Sat Feb 17 | at#8Tennessee | L53-88 | 7-18 | .280 | - | SEC Network | Thompson-Boling Arena · Knoxville, TN |
| 26 | Wed Feb 21 | vs Georgia | L64-76 | 7-19 | .269 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 27 | Sat Feb 24 | at #24Florida | L64-77 | 7-20 | .259 | - | SEC Network | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 28 | Tue Feb 27 | at Arkansas | W85-82 | 8-20 | .286 | - | SEC Network | Bud Walton Arena · Fayetteville, AR |
| 29 | Sat Mar 2 | vsLSU | L61-75 | 8-21 | .276 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 30 | Wed Mar 6 | at#15Kentucky | L77-93 | 8-22 | .267 | - | SEC Network | Rupp Arena · Lexington, KY |
| 31 | Sat Mar 9 | vsFlorida | W79-78 | 9-22 | .290 | - | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 32 | Wed Mar 13 | atArkansas | L85-90 (OT) | 9-23 | .281 | - | SEC Network | Bud Walton Arena · Fayetteville, AR |
