| 1 | Sun Sep 11 | at Titans | W21-20 | 1-0 | 1.000 | Nissan Stadium · Nashville, TN |
| 2 | Sun Sep 18 | vs Panthers | W19-16 | 2-0 | 1.000 | MetLife Stadium · East Rutherford, NJ |
| 3 | Mon Sep 26 | vs Cowboys | L16-23 | 2-1 | .667 | MetLife Stadium · East Rutherford, NJ |
| 4 | Sun Oct 2 | vs Bears | W20-12 | 3-1 | .750 | MetLife Stadium · East Rutherford, NJ |
| 5 | Sun Oct 9 | at Packers | W27-22 | 4-1 | .800 | Tottenham Hotspur Stadium · London, England |
| 6 | Sun Oct 16 | vs Ravens | W24-20 | 5-1 | .833 | MetLife Stadium · East Rutherford, NJ |
| 7 | Sun Oct 23 | at Jaguars | W23-17 | 6-1 | .857 | TIAA Bank Field · Jacksonville, FL |
| 8 | Sun Oct 30 | at Seahawks | L13-27 | 6-2 | .750 | Lumen Field · Seattle, WA |
| 9 | -- BYE WEEK -- |
| 10 | Sun Nov 13 | vs Texans | W24-16 | 7-2 | .778 | MetLife Stadium · East Rutherford, NJ |
| 11 | Sun Nov 20 | vs Lions | L18-31 | 7-3 | .700 | MetLife Stadium · East Rutherford, NJ |
| 12 | Thu Nov 24 | atCowboys | L20-28 | 7-4 | .636 | AT&T Stadium · Arlington, TX |
| 13 | Sun Dec 4 | vs Commanders | T20-20 (OT) | 7-4-1 | .636 | MetLife Stadium · East Rutherford, NJ |
| 14 | Sun Dec 11 | vs Eagles | L22-48 | 7-5-1 | .583 | MetLife Stadium · East Rutherford, NJ |
| 15 | Sun Dec 18 | atCommanders | W20-12 | 8-5-1 | .615 | FedEx Field · North Englewood, MD |
| 16 | Sat Dec 24 | at Vikings | L24-27 | 8-6-1 | .571 | U.S. Bank Stadium · Minneapolis, MN |
| 17 | Sun Jan 1 | vs Colts | W38-10 | 9-6-1 | .600 | MetLife Stadium · East Rutherford, NJ |
| 18 | Sun Jan 8 | atEagles | L16-22 | 9-7-1 | .563 | Lincoln Financial Field · Philadelphia, PA |
| WC | Sun Jan 15 | atVikings | W31-24 | 9-7-1 | .563 | U.S. Bank Stadium · Minneapolis, MN |
| DIV | Sat Jan 21 | atEagles | L7-38 | 9-7-1 | .563 | Lincoln Financial Field · Philadelphia, PA |
