| 1 | Wed Nov 5 | vs Alabama A&M | 8:00 PM | 10-22 | .313 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 2 | Sun Nov 9 | vsMarquette | 1:00 PM | 23-11 | .676 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 3 | Wed Nov 12 | vsMilwaukee | TBD | 21-11 | .656 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 4 | Sun Nov 16 | vsIncarnate Word | TBD | 19-17 | .528 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 5 | Thu Nov 20 | vsLindenwood | TBD | 16-17 | .485 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 6 | Tue Nov 25 | vsKansas St | 8:00 PM | 16-17 | .485 | - | FS1 | Simon Skjodt Assembly Hall · Bloomington, IN |
| 7 | Sat Nov 29 | vsBethune | TBD | 17-16 | .515 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 8 | Wed Dec 3 | atMinnesota | TBD | 15-17 | .469 | - | | Williams Arena · Minneapolis, MN |
| 9 | Sat Dec 6 | vs#11Louisville | 2:00 PM | 27-8 | .771 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 10 | Tue Dec 9 | vsPenn State | 8:30 PM | 16-15 | .516 | - | FS1 | Simon Skjodt Assembly Hall · Bloomington, IN |
| 11 | Sat Dec 13 | at#9Kentucky | 7:30 PM | 24-12 | .667 | - | ESPN | Rupp Arena · Lexington, KY |
| 12 | Sat Dec 20 | vsChicago St | TBD | 4-28 | .125 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 13 | Mon Dec 22 | vsSiena | TBD | 14-18 | .438 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 14 | Sun Jan 4 | vsWashington | TBD | 13-18 | .419 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 15 | Wed Jan 7 | atMaryland | TBD | 27-9 | .750 | - | | XFINITY Center · College Park, MD |
| 16 | Sat Jan 10 | vsNebraska | 12:00 PM | 21-14 | .600 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 17 | Tue Jan 13 | at#22Michigan St | TBD | 30-7 | .811 | - | | Breslin Center · East Lansing, MI |
| 18 | Sat Jan 17 | vsIowa | TBD | 17-16 | .515 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 19 | Tue Jan 20 | at#7Michigan | TBD | 27-10 | .730 | - | | Crisler Center · Ann Arbor, MI |
| 20 | Fri Jan 23 | atRutgers | TBD | 15-17 | .469 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 21 | Tue Jan 27 | vs#1Purdue | TBD | 24-12 | .667 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 22 | Sat Jan 31 | at#12UCLA | 5:00 PM | 23-11 | .676 | - | | Pauley Pavilion · Los Angeles, CA |
| 23 | Tue Feb 3 | atUSC | 10:00 PM | 17-18 | .486 | - | | Galen Center · Los Angeles, CA |
| 24 | Sat Feb 7 | vs#24Wisconsin | TBD | 27-10 | .730 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 25 | Mon Feb 9 | vsOregon | TBD | 25-10 | .714 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 26 | Sun Feb 15 | at#17Illinois | TBD | 22-13 | .629 | - | | State Farm Center · Champaign, IL |
| 27 | Fri Feb 20 | at#1Purdue | TBD | 24-12 | .667 | - | | Mackey Arena · West Lafayette, IN |
| 28 | Tue Feb 24 | vsNorthwestern | TBD | 17-16 | .515 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 29 | Sun Mar 1 | vs#22Michigan St | TBD | 30-7 | .811 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 30 | Wed Mar 4 | vsMinnesota | TBD | 15-17 | .469 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 31 | Sat Mar 7 | atOhio State | TBD | 17-15 | .531 | - | | Value City Arena · Columbus, OH |
