| 10 | Sun Dec 7 | at #21Kansas | 1:00 PM | 6-3 | .667 | - | ESPN2 | Allen Fieldhouse · Lawrence, KS |
| 11 | Thu Dec 11 | vsAlabama St | 8:00 PM | 3-5 | .375 | - | SECN+ | Mizzou Arena · Columbia, MO |
| 12 | Sun Dec 14 | vsBethune | 2:00 PM | 2-6 | .250 | - | SEC Network | Mizzou Arena · Columbia, MO |
| 13 | Mon Dec 22 | at#14Illinois | 8:00 PM | 6-2 | .750 | - | FS1 | State Farm Center · Champaign, IL |
| 14 | Sat Jan 3 | vs#15Florida | 8:30 PM | 5-3 | .625 | - | SEC Network | Mizzou Arena · Columbia, MO |
| 15 | Wed Jan 7 | at#18Kentucky | 7:00 PM | 5-3 | .625 | - | ESPN2 | Rupp Arena · Lexington, KY |
| 16 | Sat Jan 10 | atOle Miss | 6:00 PM | 5-3 | .625 | - | SEC Network | SJB Pavilion · Oxford, MS |
| 17 | Wed Jan 14 | vs#20Auburn | 7:00 PM | 7-2 | .778 | - | | Mizzou Arena · Columbia, MO |
| 18 | Sat Jan 17 | atLSU | 3:30 PM | 8-0 | 1.000 | - | SEC Network | Pete Maravich Assembly Center · Baton Rouge, LA |
| 19 | Tue Jan 20 | vsGeorgia | 9:00 PM | 8-1 | .889 | - | SEC Network | Mizzou Arena · Columbia, MO |
| 20 | Sat Jan 24 | vsOklahoma | 2:00 PM | 6-2 | .750 | - | | Mizzou Arena · Columbia, MO |
| 21 | Tue Jan 27 | at#12Alabama | 9:00 PM | 6-2 | .750 | - | SEC Network | Coleman Coliseum · Tuscaloosa, AL |
| 22 | Sat Jan 31 | vsMississippi St | 3:30 PM | 4-4 | .500 | - | SEC Network | Mizzou Arena · Columbia, MO |
| 23 | Sat Feb 7 | atSouth Carolina | 1:00 PM | 5-3 | .625 | - | SEC Network | Colonial Life Arena · Columbia, SC |
| 24 | Wed Feb 11 | atTexas A&M | 9:00 PM | 7-2 | .778 | - | SEC Network | Reed Arena · College Station, TX |
| 25 | Sat Feb 14 | vsTexas | 8:30 PM | 6-3 | .667 | - | | Mizzou Arena · Columbia, MO |
| 26 | Wed Feb 18 | vs#17Vanderbilt | 9:00 PM | 9-0 | 1.000 | - | SEC Network | Mizzou Arena · Columbia, MO |
| 27 | Sat Feb 21 | at#25Arkansas | 4:00 PM | 6-2 | .750 | - | | Bud Walton Arena · Fayetteville, AR |
| 28 | Tue Feb 24 | vs#13Tennessee | 9:00 PM | 7-2 | .778 | - | SEC Network | Mizzou Arena · Columbia, MO |
| 29 | Sat Feb 28 | atMississippi St | 1:00 PM | 4-4 | .500 | - | SEC Network | Humphrey Coliseum · Starkville, MS |
| 30 | Tue Mar 3 | atOklahoma | 7:00 PM | 6-2 | .750 | - | ESPNU | Lloyd Noble Center · Norman, OK |
| 31 | Sat Mar 7 | vs#25Arkansas | 12:00 PM | 6-2 | .750 | - | ESPN | Mizzou Arena · Columbia, MO |
