| 1 | Mon Nov 3 | vs Jackson St | 8:30 PM | 16-18 | .471 | #17 | BTN | State Farm Center · Champaign, IL |
| 2 | Fri Nov 7 | vsFGCU | 7:00 PM | 19-15 | .559 | #17 | Peacock | State Farm Center · Champaign, IL |
| 3 | Tue Nov 11 | vs#10Texas Tech | 8:30 PM | 28-9 | .757 | #17 | FS1 | State Farm Center · Champaign, IL |
| 4 | Fri Nov 14 | vsColgate | TBD | 14-19 | .424 | #17 | | State Farm Center · Champaign, IL |
| 5 | Wed Nov 19 | vs#15Alabama | TBD | 28-9 | .757 | #17 | | State Farm Center · Champaign, IL |
| 6 | Sat Nov 22 | vsLong Island | TBD | 17-16 | .515 | #17 | | State Farm Center · Champaign, IL |
| 7 | Mon Nov 24 | vsUT Rio Grande | TBD | 16-15 | .516 | #17 | | State Farm Center · Champaign, IL |
| 8 | Fri Nov 28 | vs#4UConn | 12:30 PM | 24-11 | .686 | #17 | | State Farm Center · Champaign, IL |
| 9 | Sat Dec 6 | vs#18Tennessee | 8:00 PM | 30-8 | .789 | #17 | ESPN | State Farm Center · Champaign, IL |
| 10 | Tue Dec 9 | atOhio State | TBD | 17-15 | .531 | #17 | | Value City Arena · Columbus, OH |
| 11 | Sat Dec 13 | vsNebraska | 9:00 PM | 21-14 | .600 | #17 | Peacock | State Farm Center · Champaign, IL |
| 12 | Mon Dec 22 | vsMissouri | TBD | 22-12 | .647 | #17 | | State Farm Center · Champaign, IL |
| 13 | Mon Dec 29 | vsSouthern | TBD | 20-12 | .625 | #17 | | State Farm Center · Champaign, IL |
| 14 | Sat Jan 3 | atPenn State | 7:00 PM | 16-15 | .516 | #17 | BTN | Bryce Jordan Center · University Park, PA |
| 15 | Thu Jan 8 | vsRutgers | TBD | 15-17 | .469 | #17 | | State Farm Center · Champaign, IL |
| 16 | Sun Jan 11 | atIowa | TBD | 17-16 | .515 | #17 | | Carver-Hawkeye Arena · Iowa City, IA |
| 17 | Wed Jan 14 | atNorthwestern | TBD | 17-16 | .515 | #17 | | Welsh-Ryan Arena · Evanston, IL |
| 18 | Sat Jan 17 | vsMinnesota | TBD | 15-17 | .469 | #17 | | State Farm Center · Champaign, IL |
| 19 | Wed Jan 21 | vsMaryland | TBD | 27-9 | .750 | #17 | | State Farm Center · Champaign, IL |
| 20 | Sat Jan 24 | at#1Purdue | TBD | 24-12 | .667 | #17 | | Mackey Arena · West Lafayette, IN |
| 21 | Thu Jan 29 | vsWashington | TBD | 13-18 | .419 | #17 | | State Farm Center · Champaign, IL |
| 22 | Sun Feb 1 | atNebraska | 4:00 PM | 21-14 | .600 | #17 | FS1 | Pinnacle Bank Arena · Lincoln, NE |
| 23 | Wed Feb 4 | vsNorthwestern | TBD | 17-16 | .515 | #17 | | State Farm Center · Champaign, IL |
| 24 | Sat Feb 7 | at#22Michigan St | 8:00 PM | 30-7 | .811 | #17 | | Breslin Center · East Lansing, MI |
| 25 | Tue Feb 10 | vs#24Wisconsin | TBD | 27-10 | .730 | #17 | | State Farm Center · Champaign, IL |
| 26 | Sun Feb 15 | vsIndiana | TBD | 19-13 | .594 | #17 | | State Farm Center · Champaign, IL |
| 27 | Wed Feb 18 | atUSC | 10:00 PM | 17-18 | .486 | #17 | | Galen Center · Los Angeles, CA |
| 28 | Sat Feb 21 | at#12UCLA | 8:00 PM | 23-11 | .676 | #17 | | Pauley Pavilion · Los Angeles, CA |
| 29 | Fri Feb 27 | vs#7Michigan | TBD | 27-10 | .730 | #17 | | State Farm Center · Champaign, IL |
| 30 | Tue Mar 3 | vsOregon | TBD | 25-10 | .714 | #17 | | State Farm Center · Champaign, IL |
| 31 | Sun Mar 8 | atMaryland | TBD | 27-9 | .750 | #17 | | XFINITY Center · College Park, MD |
