| 1 | Tue Nov 4 | vs Robert Morris | TBD | 26-9 | .743 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 2 | Fri Nov 7 | vsW Illinois | TBD | 12-19 | .387 | - | B1G+ | Carver-Hawkeye Arena · Iowa City, IA |
| 3 | Fri Nov 14 | vsXavier | TBD | 22-12 | .647 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 4 | Tue Nov 18 | vsSE Missouri St | TBD | 21-12 | .636 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 5 | Thu Nov 20 | vsChicago St | TBD | 4-28 | .125 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 6 | Tue Nov 25 | vsOle Miss | 9:30 PM | 24-12 | .667 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 7 | Tue Dec 2 | at#22Michigan St | TBD | 30-7 | .811 | - | | Breslin Center · East Lansing, MI |
| 8 | Sat Dec 6 | vsMaryland | TBD | 27-9 | .750 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 9 | Thu Dec 11 | at#16Iowa State | 8:00 PM | 25-10 | .714 | - | FS1 | James H. Hilton Coliseum · Ames, IA |
| 10 | Sun Dec 14 | vsW Michigan | TBD | 12-20 | .375 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 11 | Sat Dec 20 | vsBucknell | 6:00 PM | 18-15 | .545 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 12 | Mon Dec 29 | vsUMass Lowell | TBD | 17-15 | .531 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 13 | Sat Jan 3 | vs#12UCLA | 6:00 PM | 23-11 | .676 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 14 | Tue Jan 6 | atMinnesota | TBD | 15-17 | .469 | - | | Williams Arena · Minneapolis, MN |
| 15 | Sun Jan 11 | vs#17Illinois | TBD | 22-13 | .629 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 16 | Wed Jan 14 | at#1Purdue | TBD | 24-12 | .667 | - | | Mackey Arena · West Lafayette, IN |
| 17 | Sat Jan 17 | atIndiana | TBD | 19-13 | .594 | - | | Simon Skjodt Assembly Hall · Bloomington, IN |
| 18 | Tue Jan 20 | vsRutgers | TBD | 15-17 | .469 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 19 | Wed Jan 28 | vsUSC | 7:00 PM | 17-18 | .486 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 20 | Sun Feb 1 | atOregon | TBD | 25-10 | .714 | - | | Matthew Knight Arena · Eugene, OR |
| 21 | Wed Feb 4 | atWashington | TBD | 13-18 | .419 | - | | Alaska Airlines Arena · Seattle, WA |
| 22 | Sun Feb 8 | vsNorthwestern | TBD | 17-16 | .515 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 23 | Wed Feb 11 | atMaryland | TBD | 27-9 | .750 | - | | XFINITY Center · College Park, MD |
| 24 | Sat Feb 14 | vs#1Purdue | TBD | 24-12 | .667 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 25 | Tue Feb 17 | vsNebraska | 9:00 PM | 21-14 | .600 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 26 | Sun Feb 22 | at#24Wisconsin | TBD | 27-10 | .730 | - | | Kohl Center · Madison, WI |
| 27 | Wed Feb 25 | vsOhio State | TBD | 17-15 | .531 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 28 | Sat Feb 28 | atPenn State | 12:00 PM | 16-15 | .516 | - | BTN | Bryce Jordan Center · University Park, PA |
| 29 | Thu Mar 5 | vs#7Michigan | TBD | 27-10 | .730 | - | | Carver-Hawkeye Arena · Iowa City, IA |
| 30 | Sun Mar 8 | atNebraska | 5:00 PM | 21-14 | .600 | - | FOX | Pinnacle Bank Arena · Lincoln, NE |
