| 1 | Tue Nov 4 | vs Mount St Mary | 7:00 PM | 23-13 | .639 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 2 | Thu Nov 6 | vsCampbell | 7:00 PM | 15-17 | .469 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 3 | Sun Nov 9 | vsLehigh | 3:00 PM | 11-19 | .367 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 4 | Thu Nov 13 | vsPitt | 6:00 PM | 17-15 | .531 | - | FS1 | WVU Coliseum · Morgantown, WV |
| 5 | Mon Nov 17 | vsLafayette | 7:00 PM | 13-20 | .394 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 6 | Fri Nov 21 | atClemson | 6:30 PM | 27-7 | .794 | - | | Littlejohn Coliseum · Clemson, SC |
| 7 | Sun Nov 30 | vsMercyhurst | 3:00 PM | 15-16 | .484 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 8 | Wed Dec 3 | vsCoppin St | 7:00 PM | 6-24 | .200 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 9 | Sat Dec 6 | vsWake Forest | 6:00 PM | 21-11 | .656 | - | ESPNU | WVU Coliseum · Morgantown, WV |
| 10 | Tue Dec 9 | vsLittle Rock | 7:00 PM | 19-14 | .576 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 11 | Sat Dec 13 | atOhio State | 8:00 PM | 17-15 | .531 | - | ESPNU | Value City Arena · Columbus, OH |
| 12 | Mon Dec 22 | vsMiss Valley St | 7:00 PM | 3-28 | .097 | - | ESPN+ | WVU Coliseum · Morgantown, WV |
| 13 | Fri Jan 2 | at#16Iowa State | 9:00 PM | 25-10 | .714 | - | ESPN2 | James H. Hilton Coliseum · Ames, IA |
| 14 | Tue Jan 6 | vsCincinnati | 7:00 PM | 19-16 | .543 | - | ESPN2 | WVU Coliseum · Morgantown, WV |
| 15 | Sat Jan 10 | vs#19Kansas | 12:00 PM | 21-13 | .618 | - | | WVU Coliseum · Morgantown, WV |
| 16 | Tue Jan 13 | at#2Houston | 8:30 PM | 35-5 | .875 | - | FS1 | Fertitta Center · Houston, TX |
| 17 | Sat Jan 17 | vsColorado | 6:00 PM | 14-21 | .400 | - | CBS | WVU Coliseum · Morgantown, WV |
| 18 | Wed Jan 21 | atArizona St | 9:00 PM | 13-20 | .394 | - | Peacock | Desert Financial Arena · Tempe, AZ |
| 19 | Sat Jan 24 | at#13Arizona | 2:00 PM | 24-13 | .649 | - | CBS | McKale Center · Tucson, AZ |
| 20 | Tue Jan 27 | vsKansas St | 8:30 PM | 16-17 | .485 | - | FS1 | WVU Coliseum · Morgantown, WV |
| 21 | Sat Jan 31 | vsBaylor | 4:00 PM | 20-15 | .571 | - | ESPN2 | WVU Coliseum · Morgantown, WV |
| 22 | Thu Feb 5 | atCincinnati | 7:00 PM | 19-16 | .543 | - | ESPN2 | Fifth Third Arena · Cincinnati, OH |
| 23 | Sun Feb 8 | vs#10Texas Tech | 1:00 PM | 28-9 | .757 | - | FOX | WVU Coliseum · Morgantown, WV |
| 24 | Sat Feb 14 | atUCF | 6:00 PM | 20-17 | .541 | - | | Addition Financial Arena · Orlando, FL |
| 25 | Wed Feb 18 | vsUtah | 8:30 PM | 16-17 | .485 | - | FS1 | WVU Coliseum · Morgantown, WV |
| 26 | Sat Feb 21 | atTCU | 5:00 PM | 16-16 | .500 | - | Peacock | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 27 | Tue Feb 24 | atOklahoma St | 7:00 PM | 17-18 | .486 | - | CBS | Gallagher-Iba Arena · Stillwater, OK |
| 28 | Sat Feb 28 | vs#8BYU | 5:30 PM | 26-10 | .722 | - | FOX | WVU Coliseum · Morgantown, WV |
| 29 | Tue Mar 3 | atKansas St | 8:00 PM | 16-17 | .485 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 30 | Fri Mar 6 | vsUCF | 8:00 PM | 20-17 | .541 | - | CBS | WVU Coliseum · Morgantown, WV |
